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Immunogen sequence: QDASDGLQRL HMLQISYFRD PYHVWYQGNA SLGGHLTHVL EGPDTNTTII QLQPLQEPES WARTQSGLQS YLLQFHGLVR LVHQERTLAF PLTIRCFLGC ELPPEGSRAH VFFEVAVNGS SFVSFRPERA LWQADTQVTS GVVTFTLQQL NAYNRTRYEL REFLEDTCVQ YVQKHISAEN TKGSQTSRSY T
The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Activated protein C receptor; APC receptor; bA42O4.2; CD antigen CD201; CD201; CD201 antigen; cell cycle, centrosome-associated protein; Centrocyclin; Centrosomal protein CCD41; Endothelial cell protein C receptor; Endothelial protein C receptor; protein C receptor, endothelial
Gene Aliases: AI325044; CCCA; CCD41; EPCR; PROCR
UniProt ID: (Human) Q96CB3, (Rat) Q4V8I1, (Mouse) Q64695
Entrez Gene ID: (Human) 10544, (Rat) 362248, (Mouse) 19124
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