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PROK2 Antibody (PA5-98946) in WB
Western Blot analysis of PROK2 using a PROK2 Polyclonal antibody (Product # PA5-98946) at a concentration of 3 µg/mL. Positive WB detected in Mouse small intestine tissue. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:10,000 dilution. Observed band size: 9 kDa.
Product Details
PA5-98946
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Mouse Prokineticin-2 protein (27-128AA)
Conjugate
Form
Liquid
Concentration
1.5 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2813559
Target Information
Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the suprachiasmatic nucleus (SCN) with receptors located in the critical autonomic control centers of the brain. It has a depolarizing effect on neurons expressing the receptor. PK2 is predominantly controlled by the endogenous circadian clock, but light also plays a modulatory role. PK2 functions as a critical SCN output molecule responsible for circadian locomotor rhythms. PK2 expression is high during the day, and responsive to nocturnal light pulses. PK2 also functions as a chemoattractant for subventricular zone-derived neuronal progenitors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bombina variegata 8 kD protein; Bombina variegata 8kDa protein; Bv 8 homolog (Bombina variegata); PK2; prokineticin 1; Prokineticin-2; Protein Bv8 homolog
Gene Aliases: Bv8; PK2; Prok1; Prok2
UniProt ID: (Mouse) Q9QXU7
Entrez Gene ID: (Mouse) 50501
angiogenesis
epicardium-derived cardiac endothelial cell differentiation
chemotaxis
neuropeptide signaling pathway
spermatogenesis
circadian rhythm
cell proliferation
negative regulation of apoptotic process
positive regulation of smooth muscle contraction
rhythmic process
coronary vasculature development
vasculogenesis involved in coronary vascular morphogenesis
epicardium-derived cardiac vascular smooth muscle cell differentiation
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