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Immunogen sequence: ILVDHHILS KSDTALEEAV AEVLDHRPIE PKHCPPCHVS VELVGSCATL VTERILQGAP EILDRQTAAL LHGTIILDCV NMDLKIGKAT PKDSKYVEKL EALFPDLPKR NDIFDSLQKA KFDVSGLTTE QMLRKDQKTI YRQGVKVAIS AIYMDLEAFL QRSNLLADLH AFCQAHSYDV LVAMTIFFNT HNEPVRQLAI FCPHVALQTT ICEVLERSHS PPLKLTPASS THPNLHAYLQ GNTQVSRKKL LPLLQEALSA YFDSMKIPSG QPETADVSRE QVDKELDRAS NSLISGLSQD EEDPPLPPTP MNSLVDECPL DQGLPKLSAE AVFEKCSQIS LSQSTTASLS KK (103-453 aa encoded by BC025304)
Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. It plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DRES-17; Drosophila-related expressed sequence 17; Exopolyphosphatase PRUNE1; hPrune; HTcD37; protein prune homolog; Protein prune homolog 1; prune homolog; PRUNEM1
Gene Aliases: 9230112O05Rik; C130058A12; DRES-17; DRES17; H-PRUNE; HTCD37; PRUNE; Prune-M1; PRUNE1; PRUNEM1
UniProt ID: (Human) Q86TP1, (Mouse) Q8BIW1, (Rat) Q6AYG3
Entrez Gene ID: (Human) 58497, (Mouse) 229589, (Rat) 310664
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