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Positive control: Human appendix, human kidney.
The antibody may be stored at 4 C. For prolonged storage prepare appropriate aliquots and store at or below -20 C. Prior to use, an aliquot is thawed slowly in the dark at ambient temperature, spun down again and used to prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. Working dilutions should be stored at 4 C, not refrozen, and preferably used the same day. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance or the concentration of the product.
PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and is abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. PSA is used to confirm prostatic acinar cell origin in primary and metastatic carcinoma and to rule out non-prostatic carcinoma mimics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Antigen; Gamma-seminoprotein; Kallikrein 3; Kallikrein-3; Kallikrein-3 (KLK3); kallikrein-related peptidase 3; KLK-3; P-30 antigen; prostate specific antigen; prostate-specific (APS); Prostate-specific antigen; PSA; Semenogelase; Seminin
Gene Aliases: APS; hK3; KLK2A1; KLK3; PSA
UniProt ID: (Human) P07288
Entrez Gene ID: (Human) 354
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