Product References
Downregulation of PSAT1 inhibits cell proliferation and migration in uterine corpus endometrial carcinoma.
Scientific reports
Wang M,Yue S,Yang Z
Sat Mar 11 00:00:00 EST 2023
Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescence.
Nature communications
Wu Y,Tang L,Huang H,Yu Q,Hu B,Wang G,Ge F,Yin T,Li S,Yu X
Fri Mar 10 00:00:00 EST 2023
Comprehensive Analysis of Prognosis and Immune Landscapes Based on Lipid-Metabolism- and Ferroptosis-Associated Signature in Uterine Corpus Endometrial Carcinoma.
Diagnostics (Basel, Switzerland)
Yang P,Lu J,Zhang P,Zhang S
Fri Feb 24 00:00:00 EST 2023
Glutamine synthetase limits β-catenin-mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1.
The Journal of clinical investigation
Dai W,Shen J,Yan J,Bott AJ,Maimouni S,Daguplo HQ,Wang Y,Khayati K,Guo JY,Zhang L,Wang Y,Valvezan A,Ding WX,Chen X,Su X,Gao S,Zong WX
Thu Dec 15 00:00:00 EST 2022
The lncRNA PILA promotes NF-κB signaling in osteoarthritis by stimulating the activity of the protein arginine methyltransferase PRMT1.
Science signaling
Tang S,Cao Y,Cai Z,Nie X,Ruan J,Zhou Z,Ruan G,Zhu Z,Han W,Ding C
Tue May 24 00:00:00 EDT 2022
Metabolic and Nonmetabolic Functions of PSAT1 Coordinate Signaling Cascades to Confer EGFR Inhibitor Resistance and Drive Progression in Lung Adenocarcinoma.
Cancer research
Luo MY,Zhou Y,Gu WM,Wang C,Shen NX,Dong JK,Lei HM,Tang YB,Liang Q,Zou JH,Xu L,Ma P,Zhuang G,Bi L,Xu L,Zhu L,Chen HZ,Shen Y
Tue Oct 04 00:00:00 EDT 2022
Metabolic and Nonmetabolic Functions of PSAT1 Coordinate Signaling Cascades to Confer EGFR Inhibitor Resistance and Drive Progression in Lung Adenocarcinoma.
Cancer research
Luo MY,Zhou Y,Gu WM,Wang C,Shen NX,Dong JK,Lei HM,Tang YB,Liang Q,Zou JH,Xu L,Ma P,Zhuang G,Bi L,Xu L,Zhu L,Chen HZ,Shen Y
Tue Oct 04 00:00:00 EDT 2022
Monosaccharide-mediated rational synthesis of a universal plasmonic platform with broad spectral fluorescence enhancement for high-sensitivity cancer biomarker analysis.
Journal of nanobiotechnology
Liu M,Li Y,Xing W,Zhang Y,Xie X,Pang J,Zhou F,Yang J
Sun Apr 10 00:00:00 EDT 2022
Single-cell analysis of human testis aging and correlation with elevated body mass index.
Developmental cell
Nie X,Munyoki SK,Sukhwani M,Schmid N,Missel A,Emery BR,Stukenborg JB,Mayerhofer A,Orwig KE,Aston KI,Hotaling JM,Cairns BR,Guo J
Mon May 09 00:00:00 EDT 2022
Microneedle patches integrated with lateral flow cassettes for blood-free chronic kidney disease point-of-care testing during a pandemic.
Biosensors & bioelectronics
Chen YJ,Hsu YP,Tain YL,Li NS,Pang HH,Kuo SW,Yang HW
Fri Jul 15 00:00:00 EDT 2022
Ailanthone Inhibits Proliferation, Migration and Invasion of Osteosarcoma Cells by Downregulating the Serine Biosynthetic Pathway.
Frontiers in oncology
Zhang Y,Gong R,Liu Y,Sun X,Liang J,Zhou Y,Wang Y,Yu W,Wang Y,Tang L,He A,Shen Z,Yao Y,Hu H,Liu X,Zhang J
Wed Feb 23 00:00:00 EST 2022
Transcriptome and Proteome Analysis in LUHMES Cells Overexpressing Alpha-Synuclein.
Frontiers in neurology
Höllerhage M,Stepath M,Kohl M,Pfeiffer K,Chua OWH,Duan L,Hopfner F,Eisenacher M,Marcus K,Höglinger GU
Sat Apr 30 00:00:00 EDT 2022
Disrupted liver oxidative metabolism in glycine N-methyltransferase-deficient mice is mitigated by dietary methionine restriction.
Molecular metabolism
Rome FI,Hughey CC
Fri Apr 01 00:00:00 EDT 2022
PERK is a critical metabolic hub for immunosuppressive function in macrophages.
Nature immunology
Raines LN,Zhao H,Wang Y,Chen HY,Gallart-Ayala H,Hsueh PC,Cao W,Koh Y,Alamonte-Loya A,Liu PS,Ivanisevic J,Lio CJ,Ho PC,Huang SC
Tue Mar 01 00:00:00 EST 2022
Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway.
Nature communications
Soflaee MH,Kesavan R,Sahu U,Tasdogan A,Villa E,Djabari Z,Cai F,Tran DH,Vu HS,Ali ES,Rion H,O'Hara BP,Kelekar S,Hallett JH,Martin M,Mathews TP,Gao P,Asara JM,Manning BD,Ben-Sahra I,Hoxhaj G
Mon May 16 00:00:00 EDT 2022
ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway.
Acta pharmacologica Sinica
Li S,Yang H,Li W,Liu JY,Ren LW,Yang YH,Ge BB,Zhang YZ,Fu WQ,Zheng XJ,Du GH,Wang JH
Sat Oct 01 00:00:00 EDT 2022
Proteomic profile of human dental follicle stem cells and apical papilla stem cells.
Journal of proteomics
Lei T,Zhang X,Chen P,Li Q,Du H
Sat Jan 16 00:00:00 EST 2021
Serine Metabolism Controls Dental Pulp Stem Cell Aging by Regulating the DNA Methylation of p16.
Journal of dental research
Yang RL,Huang HM,Han CS,Cui SJ,Zhou YK,Zhou YH
Fri Jan 01 00:00:00 EST 2021
Serine Metabolism Controls Dental Pulp Stem Cell Aging by Regulating the DNA Methylation of p16.
Journal of dental research
Yang RL,Huang HM,Han CS,Cui SJ,Zhou YK,Zhou YH
Fri Jan 01 00:00:00 EST 2021
Serine Biosynthesis Is a Metabolic Vulnerability in IDH2-Driven Breast Cancer Progression.
Cancer research
Barnabas GD,Lee JS,Shami T,Harel M,Beck L,Selitrennik M,Jerby-Arnon L,Erez N,Ruppin E,Geiger T
Mon Mar 15 00:00:00 EDT 2021
Serine synthesis influences tamoxifen response in ER+ human breast carcinoma.
Endocrine-related cancer
Metcalf S,Petri BJ,Kruer T,Green B,Dougherty S,Wittliff JL,Klinge CM,Clem BF
Fri Jan 01 00:00:00 EST 2021
Serine metabolism antagonizes antiviral innate immunity by preventing ATP6V0d2-mediated YAP lysosomal degradation.
Cell metabolism
Shen L,Hu P,Zhang Y,Ji Z,Shan X,Ni L,Ning N,Wang J,Tian H,Shui G,Yuan Y,Li G,Zheng H,Yang XP,Huang D,Feng X,Li MJ,Liu Z,Wang T,Yu Q
Tue May 04 00:00:00 EDT 2021
Extracellular serine and glycine are required for mouse and human skeletal muscle stem and progenitor cell function.
Molecular metabolism
Gheller BJ,Blum JE,Lim EW,Handzlik MK,Hannah Fong EH,Ko AC,Khanna S,Gheller ME,Bender EL,Alexander MS,Stover PJ,Field MS,Cosgrove BD,Metallo CM,Thalacker-Mercer AE
Fri Jan 01 00:00:00 EST 2021
Bone metastatic breast cancer cells display downregulation of PKC-ζ with enhanced glutamine metabolism.
Gene
Tandon M,Othman AH,Winogradzki M,Pratap J
Mon Apr 05 00:00:00 EDT 2021
Nuclear Pyruvate Kinase M2 (PKM2) Contributes to Phosphoserine Aminotransferase 1 (PSAT1)-Mediated Cell Migration in EGFR-Activated Lung Cancer Cells.
Cancers
Biyik-Sit R,Kruer T,Dougherty S,Bradley JA,Wilkey DW,Merchant ML,Trent JO,Clem BF
Wed Aug 04 00:00:00 EDT 2021
Nuclear Pyruvate Kinase M2 (PKM2) Contributes to Phosphoserine Aminotransferase 1 (PSAT1)-Mediated Cell Migration in EGFR-Activated Lung Cancer Cells.
Cancers
Biyik-Sit R,Kruer T,Dougherty S,Bradley JA,Wilkey DW,Merchant ML,Trent JO,Clem BF
Wed Aug 04 00:00:00 EDT 2021
LncRNA MEG8 promotes NSCLC progression by modulating the miR-15a-5p-miR-15b-5p/PSAT1 axis.
Cancer cell international
Guo K,Qi D,Huang B
Mon Feb 01 00:00:00 EST 2021
Selective loss of phosphoserine aminotransferase 1 (PSAT1) suppresses migration, invasion, and experimental metastasis in triple negative breast cancer.
Clinical & experimental metastasis
Metcalf S,Dougherty S,Kruer T,Hasan N,Biyik-Sit R,Reynolds L,Clem BF
Sat Feb 01 00:00:00 EST 2020
Selective loss of phosphoserine aminotransferase 1 (PSAT1) suppresses migration, invasion, and experimental metastasis in triple negative breast cancer.
Clinical & experimental metastasis
Metcalf S,Dougherty S,Kruer T,Hasan N,Biyik-Sit R,Reynolds L,Clem BF
Sat Feb 01 00:00:00 EST 2020
The auxiliary diagnostic value of prostate-specific antigen and α-methylacyl-CoA racemase in prostate cancer.
Oncology letters
Yang D,Shi X,Lei Y,Zhou X,Chen Q
Sat Aug 01 00:00:00 EDT 2020
PSAT1 Regulated Oxidation-Reduction Balance Affects the Growth and Prognosis of Epithelial Ovarian Cancer.
OncoTargets and therapy
Zhang Y,Li J,Dong X,Meng D,Zhi X,Yuan L,Yao L
Fri Apr 15 00:00:00 EDT 2022
TGF-β Promotes Metabolic Reprogramming in Lung Fibroblasts via mTORC1-dependent ATF4 Activation.
American journal of respiratory cell and molecular biology
O'Leary EM,Tian Y,Nigdelioglu R,Witt LJ,Cetin-Atalay R,Meliton AY,Woods PS,Kimmig LM,Sun KA,Gökalp GA,Mutlu GM,Hamanaka RB
Sun Nov 01 00:00:00 EDT 2020
Overexpression of PSAT1 promotes metastasis of lung adenocarcinoma by suppressing the IRF1-IFNγ axis.
Oncogene
Chan YC,Chang YC,Chuang HH,Yang YC,Lin YF,Huang MS,Hsiao M,Yang CJ,Hua KT
Sun Mar 01 00:00:00 EST 2020
Dlgap1 negatively regulates browning of white fat cells through effects on cell proliferation and apoptosis.
Lipids in health and disease
Zhang J,Yang J,Yang N,Ma J,Lu D,Dong Y,Liang H,Liu D,Cang M
Fri Mar 13 00:00:00 EDT 2020
SOX2 has dual functions as a regulator in the progression of neuroendocrine prostate cancer.
Laboratory investigation; a journal of technical methods and pathology
Li H,Wang L,Li Z,Geng X,Li M,Tang Q,Wu C,Lu Z
Wed Apr 01 00:00:00 EDT 2020
The Symbiotic Relationship between the Neural Retina and Retinal Pigment Epithelium Is Supported by Utilizing Differential Metabolic Pathways.
iScience
Sinha T,Naash MI,Al-Ubaidi MR
Fri Apr 24 00:00:00 EDT 2020
Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism.
Cell reports
Bott AJ,Shen J,Tonelli C,Zhan L,Sivaram N,Jiang YP,Yu X,Bhatt V,Chiles E,Zhong H,Maimouni S,Dai W,Velasquez S,Pan JA,Muthalagu N,Morton J,Anthony TG,Feng H,Lamers WH,Murphy DJ,Guo JY,Jin J,Crawford HC,Zhang L,White E,Lin RZ,Su X,Tuveson DA,Zong WX
Tue Oct 29 00:00:00 EDT 2019
A novel inhibitor of tumorspheres reveals the activation of the serine biosynthetic pathway upon mitochondrial inhibition.
FEBS letters
Subedi A,Muroi M,Futamura Y,Kawamura T,Aono H,Nishi M,Ryo A,Watanabe N,Osada H
Mon Apr 01 00:00:00 EDT 2019
The SIRT2/cMYC Pathway Inhibits Peroxidation-Related Apoptosis In Cholangiocarcinoma Through Metabolic Reprogramming.
Neoplasia (New York, N.Y.)
Xu L,Wang L,Zhou L,Dorfman RG,Pan Y,Tang D,Wang Y,Yin Y,Jiang C,Zou X,Wu J,Zhang M
Wed May 01 00:00:00 EDT 2019
Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.
eLife
Zeng H,Castillo-Cabrera J,Manser M,Lu B,Yang Z,Strande V,Begue D,Zamponi R,Qiu S,Sigoillot F,Wang Q,Lindeman A,Reece-Hoyes JS,Russ C,Bonenfant D,Jiang X,Wang Y,Cong F
Tue Nov 19 00:00:00 EST 2019
Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications.
Life science alliance
Tian S,Feng J,Cao Y,Shen S,Cai Y,Yang D,Yan R,Wang L,Zhang H,Zhong X,Gao P
Tue Oct 01 00:00:00 EDT 2019
Glutamine Metabolism Is Required for Collagen Protein Synthesis in Lung Fibroblasts.
American journal of respiratory cell and molecular biology
Hamanaka RB,O'Leary EM,Witt LJ,Tian Y,Gökalp GA,Meliton AY,Dulin NO,Mutlu GM
Fri Nov 01 00:00:00 EDT 2019
De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues.
The Journal of biological chemistry
Fan TWM,Bruntz RC,Yang Y,Song H,Chernyavskaya Y,Deng P,Zhang Y,Shah PP,Beverly LJ,Qi Z,Mahan AL,Higashi RM,Dang CV,Lane AN
Fri Sep 06 00:00:00 EDT 2019
Sirtuin5 contributes to colorectal carcinogenesis by enhancing glutaminolysis in a deglutarylation-dependent manner.
Nature communications
Wang YQ,Wang HL,Xu J,Tan J,Fu LN,Wang JL,Zou TH,Sun DF,Gao QY,Chen YX,Fang JY
Wed Feb 07 00:00:00 EST 2018
Sirtuin5 contributes to colorectal carcinogenesis by enhancing glutaminolysis in a deglutarylation-dependent manner.
Nature communications
Wang YQ,Wang HL,Xu J,Tan J,Fu LN,Wang JL,Zou TH,Sun DF,Gao QY,Chen YX,Fang JY
Wed Feb 07 00:00:00 EST 2018
Serine Is an Essential Metabolite for Effector T Cell Expansion.
Cell metabolism
Ma EH,Bantug G,Griss T,Condotta S,Johnson RM,Samborska B,Mainolfi N,Suri V,Guak H,Balmer ML,Verway MJ,Raissi TC,Tsui H,Boukhaled G,Henriques da Costa S,Frezza C,Krawczyk CM,Friedman A,Manfredi M,Richer MJ,Hess C,Jones RG
Tue Feb 07 00:00:00 EST 2017
Serine Is an Essential Metabolite for Effector T Cell Expansion.
Cell metabolism
Ma EH,Bantug G,Griss T,Condotta S,Johnson RM,Samborska B,Mainolfi N,Suri V,Guak H,Balmer ML,Verway MJ,Raissi TC,Tsui H,Boukhaled G,Henriques da Costa S,Frezza C,Krawczyk CM,Friedman A,Manfredi M,Richer MJ,Hess C,Jones RG
Tue Feb 07 00:00:00 EST 2017
Serine alleviates oxidative stress via supporting glutathione synthesis and methionine cycle in mice.
Molecular nutrition & food research
Zhou X,He L,Wu C,Zhang Y,Wu X,Yin Y
Wed Nov 01 00:00:00 EDT 2017
Serine alleviates oxidative stress via supporting glutathione synthesis and methionine cycle in mice.
Molecular nutrition & food research
Zhou X,He L,Wu C,Zhang Y,Wu X,Yin Y
Wed Nov 01 00:00:00 EDT 2017
Targeting glutamine metabolism and the focal adhesion kinase additively inhibits the mammalian target of the rapamycin pathway in spheroid cancer stem-like properties of ovarian clear cell carcinoma in vitro.
International journal of oncology
Sato M,Kawana K,Adachi K,Fujimoto A,Yoshida M,Nakamura H,Nishida H,Inoue T,Taguchi A,Ogishima J,Eguchi S,Yamashita A,Tomio K,Wada-Hiraike O,Oda K,Nagamatsu T,Osuga Y,Fujii T
Sat Apr 01 00:00:00 EDT 2017
Targeting glutamine metabolism and the focal adhesion kinase additively inhibits the mammalian target of the rapamycin pathway in spheroid cancer stem-like properties of ovarian clear cell carcinoma in vitro.
International journal of oncology
Sato M,Kawana K,Adachi K,Fujimoto A,Yoshida M,Nakamura H,Nishida H,Inoue T,Taguchi A,Ogishima J,Eguchi S,Yamashita A,Tomio K,Wada-Hiraike O,Oda K,Nagamatsu T,Osuga Y,Fujii T
Sat Apr 01 00:00:00 EDT 2017
A simple method based on Sanger sequencing and MS Word wildcard searching to identify Cas9-induced frameshift mutations.
Laboratory investigation; a journal of technical methods and pathology
Jie H,Li Z,Wang P,Zhao L,Zhang Q,Yao X,Song X,Zhao Y,Yao S
Fri Dec 01 00:00:00 EST 2017
Stem cell function and stress response are controlled by protein synthesis.
Nature
Blanco S,Bandiera R,Popis M,Hussain S,Lombard P,Aleksic J,Sajini A,Tanna H,Cortés-Garrido R,Gkatza N,Dietmann S,Frye M
Thu Jun 16 00:00:00 EDT 2016
Overexpression of Phosphoserine Aminotransferase 1 (PSAT1) Predicts Poor Prognosis and Associates with Tumor Progression in Human Esophageal Squamous Cell Carcinoma.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Liu B,Jia Y,Cao Y,Wu S,Jiang H,Sun X,Ma J,Yin X,Mao A,Shang M
Fri Feb 10 00:00:00 EST 2017
Overexpression of Phosphoserine Aminotransferase 1 (PSAT1) Predicts Poor Prognosis and Associates with Tumor Progression in Human Esophageal Squamous Cell Carcinoma.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Liu B,Jia Y,Cao Y,Wu S,Jiang H,Sun X,Ma J,Yin X,Mao A,Shang M
Fri Feb 10 00:00:00 EST 2017
Overexpression of Phosphoserine Aminotransferase 1 (PSAT1) Predicts Poor Prognosis and Associates with Tumor Progression in Human Esophageal Squamous Cell Carcinoma.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Liu B,Jia Y,Cao Y,Wu S,Jiang H,Sun X,Ma J,Yin X,Mao A,Shang M
Fri Feb 10 00:00:00 EST 2017
Overexpression of Phosphoserine Aminotransferase 1 (PSAT1) Predicts Poor Prognosis and Associates with Tumor Progression in Human Esophageal Squamous Cell Carcinoma.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Liu B,Jia Y,Cao Y,Wu S,Jiang H,Sun X,Ma J,Yin X,Mao A,Shang M
Fri Feb 10 00:00:00 EST 2017
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Cell research
Sun L,Song L,Wan Q,Wu G,Li X,Wang Y,Wang J,Liu Z,Zhong X,He X,Shen S,Pan X,Li A,Wang Y,Gao P,Tang H,Zhang H
Wed Apr 01 00:00:00 EDT 2015
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Cell research
Sun L,Song L,Wan Q,Wu G,Li X,Wang Y,Wang J,Liu Z,Zhong X,He X,Shen S,Pan X,Li A,Wang Y,Gao P,Tang H,Zhang H
Wed Apr 01 00:00:00 EDT 2015
MicroRNA-340 Inhibits Esophageal Cancer Cell Growth and Invasion by Targeting Phosphoserine Aminotransferase 1.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Yan S,Jiang H,Fang S,Yin F,Wang Z,Jia Y,Sun X,Wu S,Jiang T,Mao A
Wed May 25 00:00:00 EDT 2016
MicroRNA-340 Inhibits Esophageal Cancer Cell Growth and Invasion by Targeting Phosphoserine Aminotransferase 1.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Yan S,Jiang H,Fang S,Yin F,Wang Z,Jia Y,Sun X,Wu S,Jiang T,Mao A
Wed May 25 00:00:00 EDT 2016
Proteomic characterization of ovarian cancers identifying annexin-A4, phosphoserine aminotransferase, cellular retinoic acid-binding protein 2, and serpin B5 as histology-specific biomarkers.
Cancer science
Toyama A,Suzuki A,Shimada T,Aoki C,Aoki Y,Umino Y,Nakamura Y,Aoki D,Sato TA
Sun Apr 01 00:00:00 EDT 2012
Proteomic characterization of ovarian cancers identifying annexin-A4, phosphoserine aminotransferase, cellular retinoic acid-binding protein 2, and serpin B5 as histology-specific biomarkers.
Cancer science
Toyama A,Suzuki A,Shimada T,Aoki C,Aoki Y,Umino Y,Nakamura Y,Aoki D,Sato TA
Sun Apr 01 00:00:00 EDT 2012
Proteomic characterization of ovarian cancers identifying annexin-A4, phosphoserine aminotransferase, cellular retinoic acid-binding protein 2, and serpin B5 as histology-specific biomarkers.
Cancer science
Toyama A,Suzuki A,Shimada T,Aoki C,Aoki Y,Umino Y,Nakamura Y,Aoki D,Sato TA
Sun Apr 01 00:00:00 EDT 2012
Proteomic characterization of ovarian cancers identifying annexin-A4, phosphoserine aminotransferase, cellular retinoic acid-binding protein 2, and serpin B5 as histology-specific biomarkers.
Cancer science
Toyama A,Suzuki A,Shimada T,Aoki C,Aoki Y,Umino Y,Nakamura Y,Aoki D,Sato TA
Sun Apr 01 00:00:00 EDT 2012
