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PSAT1 Polyclonal Antibody

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Antibody Testing Data (8)

PSAT1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 8

PSAT1 Antibody (20180-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells, using PSAT1 antibody 20180-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

PSAT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

20180-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 6 publications 6 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:10-1:100

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PSAT1 Fusion Protein Ag14044 (1-370 aa encoded by BC001618)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.23 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MDAPRQVVN FGPGPAKLPH SVLLEIQKEL LDYKGVGISV LEMSHRSSDF AKIINNTENL VRELLAVPDN YKVIFLQGGG CGQFSAVPLN LIGLKAGRCA DYVVTGAWSA KAAEEAKKFG TINIVHPKLG SYTKIPDPST WNLNPDASYV YYCANETVHG VEFDFIPDVK GAVLVCDMSS NFLSKPVDVS KFGVIFAGAQ KNVGSAGVTV VIVRDDLLGF ALRECPSVLE YKVQAGNSSL YNTPPCFSIY VMGLVLEWIK NNGGAAAMEK LSSIKSQTIY EIIDNSQGFY VCPVEPQNRS KMNIPFRIGN AKGDDALEKR FLDKALELNM LSLKGHRSVG GIRASLYNAV TIEDVQKLAA FMKKFLEMHQ L (1-370 aa encoded by BC001618)

Target Information

The protein encoded by this gene is likely a phosphoserine aminotransferase, based on similarity to proteins in mouse, rabbit, and Drosophila. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells.

Proceedings of the National Academy of Sciences of the United States of America

Wang J,Filippakis H,Hougard T,Du H,Ye C,Liu HJ,Zhang L,Hindi K,Bagwe S,Nijmeh J,Asara JM,Shi W,El-Chemaly S,Henske EP,Lam HC

Tue Sep 28 00:00:00 EDT 2021

Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin.

Molecular metabolism

Byles V,Cormerais Y,Kalafut K,Barrera V,Hughes Hallett JE,Sui SH,Asara JM,Adams CM,Hoxhaj G,Ben-Sahra I,Manning BD

Mon Nov 01 00:00:00 EDT 2021

The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals.

eLife

Torrence ME,MacArthur MR,Hosios AM,Valvezan AJ,Asara JM,Mitchell JR,Manning BD

Mon Mar 01 00:00:00 EST 2021

Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway.

EMBO molecular medicine

Wilcz-Villega E,Carter E,Ironside A,Xu R,Mataloni I,Holdsworth J,Jones W,Moreno Béjar R,Uhlik L,Bentham RB,Godinho SA,Dalli J,Grose R,Szabadkai G,Jones L,Hodivala-Dilke K,Bianchi K

Fri Feb 07 00:00:00 EST 2020

Identifying strategies to target the metabolic flexibility of tumours.

Nature metabolism

Méndez-Lucas A,Lin W,Driscoll PC,Legrave N,Novellasdemunt L,Xie C,Charles M,Wilson Z,Jones NP,Rayport S,Rodríguez-Justo M,Li V,MacRae JI,Hay N,Chen X,Yuneva M

Wed Apr 01 00:00:00 EDT 2020

The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism.

EMBO reports

Xu R,Jones W,Wilcz-Villega E,Costa AS,Rajeeve V,Bentham RB,Bryson K,Nagano A,Yaman B,Olendo Barasa S,Wang Y,Chelala C,Cutillas P,Szabadkai G,Frezza C,Bianchi K

Thu Sep 03 00:00:00 EDT 2020

Metabolic reprogramming and Notch activity distinguish between non-small cell lung cancer subtypes.

British journal of cancer

Sellers K,Allen TD,Bousamra M,Tan J,Méndez-Lucas A,Lin W,Bah N,Chernyavskaya Y,MacRae JI,Higashi RM,Lane AN,Fan TW,Yuneva MO

Mon Jul 01 00:00:00 EDT 2019

mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle.

Science (New York, N.Y.)

Ben-Sahra I,Hoxhaj G,Ricoult SJH,Asara JM,Manning BD

Fri Feb 12 00:00:00 EST 2016

mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle.

Science (New York, N.Y.)

Ben-Sahra I,Hoxhaj G,Ricoult SJH,Asara JM,Manning BD

Fri Feb 12 00:00:00 EST 2016

Bioinformatics

Protein Aliases: endometrial progesterone-induced protein; Phosphohydroxythreonine aminotransferase; Phosphoserine aminotransferase; PSAT

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Gene Aliases: EPIP; NLS2; PSA; PSAT; PSAT1; PSATD

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UniProt ID: (Human) Q9Y617

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Entrez Gene ID: (Human) 29968

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Function(s)

O-phospho-L-serine:2-oxoglutarate aminotransferase activity transaminase

Process(es)

L-serine biosynthetic process pyridoxine biosynthetic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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PSAT1 Polyclonal Antibody

PSAT1 Antibody (20180-1-AP) in ICC/IF

Product Details

20180-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Miscellaneous PubMed (Misc)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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