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QED Bioscience
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J rUniProtKB:P12956, PubMed:12145306}.
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Protein Aliases: 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Imp5; importin beta-3 subunit; Importin subunit beta-3; Importin-5; karyopherin (importin) beta 3; Karyopherin beta-3; Ku autoantigen, 80kDa; Ku80; Ku86; Ku86 autoantigen related protein 1; Lupus Ku autoantigen protein p86; Nuclear factor IV; RAN binding protein 5; Ran-binding protein 5; Ran_GTP binding protein 5; RanBP5; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining); X-ray repair cross-complementing protein 5
Gene Aliases: G22P2; IMB3; imp5; IPO5; KARP-1; KARP1; KPNB3; KU80; Ku86; KUB2; NFIV; Pse1; RANBP5; XRCC5
UniProt ID: (Human) O00410, (Human) P13010
Entrez Gene ID: (Human) 3843, (Human) 7520
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