Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGPLSAPPCT QRITWKGLLL TALLLNFWNL PTTAQVTIEA EPTKVSKGKD VLLLVHNLPQ NLAGYIWYKG QMKDLYHYIT SYVVDGQIII YGPAYSGRET VYSNASLLIQ NVTREDAGSY TLHIVKRGDG TRGETGHFTF TLYLETPKPS ISSSNLYPRE DMEAVSLTCD PETPDASYLW WMNGQSLPMT HSLQLSKNKR TLFLFGVTKY TAGPYECEIR NPVSASRSDP VTLNLLPKLP KPYITINNLN PRENKDVLAF TCEPKSENYT YIWWLNGQSL PVSPRVKRPI ENRILILPSV TRNETGPYQC EIQDRYGGIR SYPVTLNVLY GPDLPRIYPS FTYYHSGENL YLSCFADSNP PAEYSWTING KFQLSGQKLF IPQITTKHSG LYACSVRNSA TGMESSKSMT VEVSAPSGTG HLPGLNPL
The pregnancy-specific glycoproteins (PSGs) are a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. Members of the PSG protein family share a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSGs function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. Eleven human PSG proteins (PSG1-PSG11) have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Carcinoembryonic antigen SG5; Pregnancy-specific beta-1-glycoprotein 3; pregnancy-specific glycoprotein 3; PS-beta-G-3; PSBG-3; sg5
Gene Aliases: PSG3
UniProt ID: (Human) Q16557
Entrez Gene ID: (Human) 5671
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