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Product Details
11196-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PSMC1 Fusion Protein Ag1677 (77-440 aa encoded by BC016368)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EFIRNQEQM KPLEEKQEEE RSKVDDLRGT PMSVGTLEEI IDDNRAIVST SVGSEHYVSI LSFVDKDLLE PGCSVLLNHK VHAVIGVLMD DTDPLVTVMK VEKAPQETYA DIGGLDNQIQ EIKESVELPL THPEYYEEMG IKPPKGVILY GPPGTGKTLL AKAVANQTSA TFLRVVGSEL IQKYLGDGPK LVRELFRVAE EHAPSIVFID EIDAIGTKRY DSNSGGEREI QRTMLELLNQ LDGFDSRGDV KVIMATNRIE TLDPALIRPG RIDRKIEFPL PDEKTKKRIF QIHTSRMTLA DDVTLDDLIM AKDDLSGADI KAICTEAGLM ALRERRMKVT NEDFKKSKEN VLYKKQEGTP EGLYL (77-440 aa encoded by B C016368)
Target Information
The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 26S protease regulatory subunit 4; 26S proteasome AAA-ATPase subunit RPT2; 26S proteasome regulatory subunit 4; MGC24583; MGC8541; P26s4; peptidase (prosome, macropain) 26S subunit, ATPase 1; protease (prosome, macropain) 26S subunit, ATPase 1; proteasome (prosome, macropain) 26S subunit, ATPase, 1; proteasome 26S ATPase subunit 1; Proteasome 26S subunit ATPase 1; proteasome 26S subunit, ATPase, 1; prs4
Gene Aliases: AI325227; P26S4; p56; PSMC1; rpt2; Rpt2/S4; S4
UniProt ID: (Human) P62191, (Rat) P62193, (Mouse) P62192
Entrez Gene ID: (Human) 5700, (Rat) 117263, (Mouse) 19179
MAPK cascade
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
regulation of cellular amino acid metabolic process
ER-associated ubiquitin-dependent protein catabolic process
anaphase-promoting complex-dependent catabolic process
tumor necrosis factor-mediated signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
T cell receptor signaling pathway
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
negative regulation of neuron death
positive regulation of proteasomal protein catabolic process
biological_process
protein catabolic process
Performance Guarantee
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