Product References
Disruption of the nuclear localization signal in RBM20 is causative in dilated cardiomyopathy.
JCI insight
Zhang Y,Gregorich ZR,Wang Y,Braz CU,Zhang J,Liu Y,Liu P,Shen J,Aori N,Hacker TA,Granzier H,Guo W
32-4800 was used in Western Blotting to reveal that disruption of RS domain-mediated nuclear localization is crucial for severe DCM caused by NLS mutations.
Mon Jul 10 00:00:00 EDT 2023
The PTBP1‑NCOA4 axis promotes ferroptosis in liver cancer cells.
Oncology reports
Yang H,Sun W,Bi T,Wang Q,Wang W,Xu Y,Liu Z,Li J
32-4800 was used in Immunoprecipitation to show that silencing of PTBP1 decreased the sensitivity of liver cancer cells to ferroptosis after SF treatment and regulated ferritinophagy by mediating NCOA4 translation.
Wed Feb 01 00:00:00 EST 2023
Hyperglycemia exacerbates dengue virus infection by facilitating poly(A)-binding protein-mediated viral translation.
JCI insight
Shen TJ,Chen CL,Tsai TT,Jhan MK,Bai CH,Yen YC,Tsai CW,Lee CY,Tseng PC,Yu CY,Lin CF
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Western Blot
Tue Nov 08 00:00:00 EST 2022
Mutated lncRNA increase the risk of type 2 diabetes by promoting β cell dysfunction and insulin resistance.
Cell death & disease
Guo WH,Guo Q,Liu YL,Yan DD,Jin L,Zhang R,Yan J,Luo XH,Yang M
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Immunocytochemistry
Thu Oct 27 00:00:00 EDT 2022
Mutated lncRNA increase the risk of type 2 diabetes by promoting β cell dysfunction and insulin resistance.
Cell death & disease
Guo WH,Guo Q,Liu YL,Yan DD,Jin L,Zhang R,Yan J,Luo XH,Yang M
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Immunocytochemistry
Thu Oct 27 00:00:00 EDT 2022
Blocking lncRNA-SNHG16 sensitizes gastric cancer cells to 5-Fu through targeting the miR-506-3p-PTBP1-mediated glucose metabolism.
Cancer & metabolism
Ding Y,Gao S,Zheng J,Chen X
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in RNA Immunoprecipitation
Tue Nov 29 00:00:00 EST 2022
Blocking lncRNA-SNHG16 sensitizes gastric cancer cells to 5-Fu through targeting the miR-506-3p-PTBP1-mediated glucose metabolism.
Cancer & metabolism
Ding Y,Gao S,Zheng J,Chen X
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in RNA Immunoprecipitation
Tue Nov 29 00:00:00 EST 2022
The selenoprotein P 3' untranslated region is an RNA binding protein platform that fine tunes selenocysteine incorporation.
PloS one
Shetty SP,Kiledjian NT,Copeland PR
32-4800 was used in Western Blotting to find that these sequences are involved in regulating SELENOP mRNA and protein levels, which are inversely altered as a function of selenium concentrations.
Tue Aug 02 00:00:00 EDT 2022
The selenoprotein P 3' untranslated region is an RNA binding protein platform that fine tunes selenocysteine incorporation.
PloS one
Shetty SP,Kiledjian NT,Copeland PR
32-4800 was used in Western Blotting to find that these sequences are involved in regulating SELENOP mRNA and protein levels, which are inversely altered as a function of selenium concentrations.
Tue Aug 02 00:00:00 EDT 2022
The alternative splicing of intersectin 1 regulated by PTBP1 promotes human glioma progression.
Cell death & disease
Lan C,Zhang H,Wang K,Liu X,Zhao Y,Guo Z,Zhang N,Zhou Y,Gao M,Gu F,Ma Y
32-4800 was used in RNA Immunoprecipitation and Western Blot to study how the intersectin 1 (ITSN1) two isoforms, ITSN1-S and ITSN1-L, are positively correlated with glioma grading and poor prognosis.
Wed Sep 28 00:00:00 EDT 2022
The alternative splicing of intersectin 1 regulated by PTBP1 promotes human glioma progression.
Cell death & disease
Lan C,Zhang H,Wang K,Liu X,Zhao Y,Guo Z,Zhang N,Zhou Y,Gao M,Gu F,Ma Y
32-4800 was used in RNA Immunoprecipitation and Western Blot to study how the intersectin 1 (ITSN1) two isoforms, ITSN1-S and ITSN1-L, are positively correlated with glioma grading and poor prognosis.
Wed Sep 28 00:00:00 EDT 2022
The alternative splicing of intersectin 1 regulated by PTBP1 promotes human glioma progression.
Cell death & disease
Lan C,Zhang H,Wang K,Liu X,Zhao Y,Guo Z,Zhang N,Zhou Y,Gao M,Gu F,Ma Y
32-4800 was used in RNA Immunoprecipitation and Western Blot to study how the intersectin 1 (ITSN1) two isoforms, ITSN1-S and ITSN1-L, are positively correlated with glioma grading and poor prognosis.
Wed Sep 28 00:00:00 EDT 2022
Polypyrimidine tract binding protein 1 regulates the activation of mouse CD8 T cells.
European journal of immunology
D'Angeli V,Monzón-Casanova E,Matheson LS,Gizlenci Ö,Petkau G,Gooding C,Berrens RV,Smith CWJ,Turner M
32-4800 was used in Flow cytometry/Cell sorting to reveal a crucial role for PTBP1 in regulating CD8 T-cell activation.
Fri Jul 01 00:00:00 EDT 2022
Cardiovirus leader proteins retarget RSK kinases toward alternative substrates to perturb nucleocytoplasmic traffic.
PLoS pathogens
Lizcano-Perret B,Lardinois C,Wavreil F,Hauchamps P,Herinckx G,Sorgeloos F,Vertommen D,Gatto L,Michiels T
32-4800 was used in Immunocytochemistry-immunofluorescence to illustrate a novel virulence mechanism where pathogens' proteins hijack and retarget cellular protein kinases toward specific substrates, to promote their replication or to escape immunity.
Thu Dec 01 00:00:00 EST 2022
Regulation of RNA localization during oocyte maturation by dynamic RNA-ER association and remodeling of the ER.
Cell reports
Hwang H,Yun S,Arcanjo RB,Chen S,Mei W,Nowak RA,Kwon T,Yang J
32-4800 was used in Western Blotting to demonstrate that dynamic regulation of RNA-ER association and remodeling of the ER are important for the asymmetric localization of RNAs during development.
Tue Dec 13 00:00:00 EST 2022
Histone marks regulate the epithelial-to-mesenchymal transition via alternative splicing.
Cell reports
Segelle A,Núñez-Álvarez Y,Oldfield AJ,Webb KM,Voigt P,Luco RF
32-4800 was used in Immunoprecipitation to address the dynamic role of chromatin marks in driving the splicing changes necessary to impact the cell’s phenotype during epithelial-to-mesenchymal transition cell reprogramming.
Tue Feb 15 00:00:00 EST 2022
Identification of human long noncoding RNAs associated with nonalcoholic fatty liver disease and metabolic homeostasis.
The Journal of clinical investigation
Ruan X,Li P,Ma Y,Jiang CF,Chen Y,Shi Y,Gupta N,Seifuddin F,Pirooznia M,Ohnishi Y,Yoneda N,Nishiwaki M,Dumbovic G,Rinn JL,Higuchi Y,Kawai K,Suemizu H,Cao H
32-4800 was used in Western Blot, RNA Immunoprecipitation, ChIP assay to identify hLMRs which are metabolically sensitive and applicable in treating disease.
Mon Jan 04 00:00:00 EST 2021
Identification of human long noncoding RNAs associated with nonalcoholic fatty liver disease and metabolic homeostasis.
The Journal of clinical investigation
Ruan X,Li P,Ma Y,Jiang CF,Chen Y,Shi Y,Gupta N,Seifuddin F,Pirooznia M,Ohnishi Y,Yoneda N,Nishiwaki M,Dumbovic G,Rinn JL,Higuchi Y,Kawai K,Suemizu H,Cao H
32-4800 was used in Western Blot, RNA Immunoprecipitation, ChIP assay to identify hLMRs which are metabolically sensitive and applicable in treating disease.
Mon Jan 04 00:00:00 EST 2021
Identification of human long noncoding RNAs associated with nonalcoholic fatty liver disease and metabolic homeostasis.
The Journal of clinical investigation
Ruan X,Li P,Ma Y,Jiang CF,Chen Y,Shi Y,Gupta N,Seifuddin F,Pirooznia M,Ohnishi Y,Yoneda N,Nishiwaki M,Dumbovic G,Rinn JL,Higuchi Y,Kawai K,Suemizu H,Cao H
32-4800 was used in Western Blot, RNA Immunoprecipitation, ChIP assay to identify hLMRs which are metabolically sensitive and applicable in treating disease.
Mon Jan 04 00:00:00 EST 2021
The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction.
Nucleic acids research
Smith EM,Benbahouche NEH,Morris K,Wilczynska A,Gillen S,Schmidt T,Meijer HA,Jukes-Jones R,Cain K,Jones C,Stoneley M,Waldron JA,Bell C,Fonseca BD,Blagden S,Willis AE,Bushell M
32-4800 was used in Western Blotting to demonstrate that mRNAs, including those encoding proteins critical for cell growth and survival, are translationally repressed when bound by both LARP1 and PABPC1.
Mon Jan 11 00:00:00 EST 2021
Essential requirement for polypyrimidine tract binding proteins 1 and 3 in the maturation and maintenance of mature B cells in mice.
European journal of immunology
Monzón-Casanova E,Bates KJ,Smith CWJ,Turner M
32-4800 was used in Flow Cytometry to show that the polypyrimidine tract binding proteins (PTBP) PTBP1 and PTBP3 bind to a large and overlapping set of transcripts in B cells.
Wed Sep 01 00:00:00 EDT 2021
Tumor suppressor SMAR1 regulates PKM alternative splicing by HDAC6-mediated deacetylation of PTBP1.
Cancer & metabolism
Choksi A,Parulekar A,Pant R,Shah VK,Nimma R,Firmal P,Singh S,Kundu GC,Shukla S,Chattopadhyay S
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Immunoprecipitation
Fri Apr 16 00:00:00 EDT 2021
Tumor suppressor SMAR1 regulates PKM alternative splicing by HDAC6-mediated deacetylation of PTBP1.
Cancer & metabolism
Choksi A,Parulekar A,Pant R,Shah VK,Nimma R,Firmal P,Singh S,Kundu GC,Shukla S,Chattopadhyay S
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Immunoprecipitation
Fri Apr 16 00:00:00 EDT 2021
The human nucleoporin Tpr protects cells from RNA-mediated replication stress.
Nature communications
Kosar M,Giannattasio M,Piccini D,Maya-Mendoza A,García-Benítez F,Bartkova J,Barroso SI,Gaillard H,Martini E,Restuccia U,Ramirez-Otero MA,Garre M,Verga E,Andújar-Sánchez M,Maynard S,Hodny Z,Costanzo V,Kumar A,Bachi A,Aguilera A,Bartek J,Foiani M
32-4800 was used in Western Blot to demonstrate the effects of human nucleoporin Tpr deletion on DNA breaks and genomic instability.
Thu Jun 24 00:00:00 EDT 2021
SINEUP long non-coding RNA acts via PTBP1 and HNRNPK to promote translational initiation assemblies.
Nucleic acids research
Toki N,Takahashi H,Sharma H,Valentine MNZ,Rahman FM,Zucchelli S,Gustincich S,Carninci P
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Western Blot
Wed Nov 18 00:00:00 EST 2020
SINEUP long non-coding RNA acts via PTBP1 and HNRNPK to promote translational initiation assemblies.
Nucleic acids research
Toki N,Takahashi H,Sharma H,Valentine MNZ,Rahman FM,Zucchelli S,Gustincich S,Carninci P
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Western Blot
Wed Nov 18 00:00:00 EST 2020
SINEUP long non-coding RNA acts via PTBP1 and HNRNPK to promote translational initiation assemblies.
Nucleic acids research
Toki N,Takahashi H,Sharma H,Valentine MNZ,Rahman FM,Zucchelli S,Gustincich S,Carninci P
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Western Blot
Wed Nov 18 00:00:00 EST 2020
SINEUP long non-coding RNA acts via PTBP1 and HNRNPK to promote translational initiation assemblies.
Nucleic acids research
Toki N,Takahashi H,Sharma H,Valentine MNZ,Rahman FM,Zucchelli S,Gustincich S,Carninci P
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Western Blot
Wed Nov 18 00:00:00 EST 2020
SINEUP long non-coding RNA acts via PTBP1 and HNRNPK to promote translational initiation assemblies.
Nucleic acids research
Toki N,Takahashi H,Sharma H,Valentine MNZ,Rahman FM,Zucchelli S,Gustincich S,Carninci P
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Western Blot
Wed Nov 18 00:00:00 EST 2020
SINEUP long non-coding RNA acts via PTBP1 and HNRNPK to promote translational initiation assemblies.
Nucleic acids research
Toki N,Takahashi H,Sharma H,Valentine MNZ,Rahman FM,Zucchelli S,Gustincich S,Carninci P
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Western Blot
Wed Nov 18 00:00:00 EST 2020
SINEUP long non-coding RNA acts via PTBP1 and HNRNPK to promote translational initiation assemblies.
Nucleic acids research
Toki N,Takahashi H,Sharma H,Valentine MNZ,Rahman FM,Zucchelli S,Gustincich S,Carninci P
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Western Blot
Wed Nov 18 00:00:00 EST 2020
Synthetic in vitro transcribed lncRNAs (SINEUPs) with chemical modifications enhance target mRNA translation.
FEBS letters
Toki N,Takahashi H,Zucchelli S,Gustincich S,Carninci P
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Western Blot
Tue Dec 01 00:00:00 EST 2020
Synthetic in vitro transcribed lncRNAs (SINEUPs) with chemical modifications enhance target mRNA translation.
FEBS letters
Toki N,Takahashi H,Zucchelli S,Gustincich S,Carninci P
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Western Blot
Tue Dec 01 00:00:00 EST 2020
RNA-binding protein Ptbp1 regulates alternative splicing and transcriptome in spermatogonia and maintains spermatogenesis in concert with Nanos3.
The Journal of reproduction and development
Senoo M,Hozoji H,Ishikawa-Yamauchi Y,Takijiri T,Ohta S,Ukai T,Kabata M,Yamamoto T,Yamada Y,Ikawa M,Ozawa M
32-4800 was used in RNA Immunoprecipitation to determine changes of AS or transcriptome in Ptbp1-knockout (KO) germline stem cells (GSC), an in vitro model of proliferating spermatogonia, by next generation sequencing.
Tue Oct 13 00:00:00 EDT 2020
RNA-binding protein Ptbp1 regulates alternative splicing and transcriptome in spermatogonia and maintains spermatogenesis in concert with Nanos3.
The Journal of reproduction and development
Senoo M,Hozoji H,Ishikawa-Yamauchi Y,Takijiri T,Ohta S,Ukai T,Kabata M,Yamamoto T,Yamada Y,Ikawa M,Ozawa M
32-4800 was used in RNA Immunoprecipitation to determine changes of AS or transcriptome in Ptbp1-knockout (KO) germline stem cells (GSC), an in vitro model of proliferating spermatogonia, by next generation sequencing.
Tue Oct 13 00:00:00 EDT 2020
RNA-binding protein Ptbp1 regulates alternative splicing and transcriptome in spermatogonia and maintains spermatogenesis in concert with Nanos3.
The Journal of reproduction and development
Senoo M,Hozoji H,Ishikawa-Yamauchi Y,Takijiri T,Ohta S,Ukai T,Kabata M,Yamamoto T,Yamada Y,Ikawa M,Ozawa M
32-4800 was used in RNA Immunoprecipitation to determine changes of AS or transcriptome in Ptbp1-knockout (KO) germline stem cells (GSC), an in vitro model of proliferating spermatogonia, by next generation sequencing.
Tue Oct 13 00:00:00 EDT 2020
RNA-binding protein Ptbp1 regulates alternative splicing and transcriptome in spermatogonia and maintains spermatogenesis in concert with Nanos3.
The Journal of reproduction and development
Senoo M,Hozoji H,Ishikawa-Yamauchi Y,Takijiri T,Ohta S,Ukai T,Kabata M,Yamamoto T,Yamada Y,Ikawa M,Ozawa M
32-4800 was used in RNA Immunoprecipitation to determine changes of AS or transcriptome in Ptbp1-knockout (KO) germline stem cells (GSC), an in vitro model of proliferating spermatogonia, by next generation sequencing.
Tue Oct 13 00:00:00 EDT 2020
Intronic Determinants Coordinate Charme lncRNA Nuclear Activity through the Interaction with MATR3 and PTBP1.
Cell reports
Desideri F,Cipriano A,Petrezselyova S,Buonaiuto G,Santini T,Kasparek P,Prochazka J,Janson G,Paiardini A,Calicchio A,Colantoni A,Sedlacek R,Bozzoni I,Ballarino M
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in In Situ Hybridization (ISH)
Tue Dec 22 00:00:00 EST 2020
Intronic Determinants Coordinate Charme lncRNA Nuclear Activity through the Interaction with MATR3 and PTBP1.
Cell reports
Desideri F,Cipriano A,Petrezselyova S,Buonaiuto G,Santini T,Kasparek P,Prochazka J,Janson G,Paiardini A,Calicchio A,Colantoni A,Sedlacek R,Bozzoni I,Ballarino M
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in In Situ Hybridization (ISH)
Tue Dec 22 00:00:00 EST 2020
The Long Noncoding RNA Pnky Is a Trans-acting Regulator of Cortical Development In Vivo.
Developmental cell
Andersen RE,Hong SJ,Lim JJ,Cui M,Harpur BA,Hwang E,Delgado RN,Ramos AD,Liu SJ,Blencowe BJ,Lim DA
32-4800 was used in Immunoprecipitation to investigate the effects of deletion of Pnky during development on the production of projection neurones and neural stem cells.
Mon May 20 00:00:00 EDT 2019
H19 potentiates let-7 family expression through reducing PTBP1 binding to their precursors in cholestasis.
Cell death & disease
Zhang L,Yang Z,Huang W,Wu J
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Western Blot
Mon Feb 18 00:00:00 EST 2019
Internal Ribosome Entry Site Dramatically Reduces Transgene Expression in Hematopoietic Cells in a Position-Dependent Manner.
Viruses
Zheng Q,Zhang X,Yang H,Xie J,Xie Y,Chen J,Yu C,Zhong C
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Western Blot
Tue Oct 08 00:00:00 EDT 2019
The RNA-binding protein PTBP1 is necessary for B cell selection in germinal centers.
Nature immunology
Monzón-Casanova E,Screen M,Díaz-Muñoz MD,Coulson RMR,Bell SE,Lamers G,Solimena M,Smith CWJ,Turner M
Thu Mar 01 00:00:00 EST 2018
A Short Tandem Repeat-Enriched RNA Assembles a Nuclear Compartment to Control Alternative Splicing and Promote Cell Survival.
Molecular cell
Yap K,Mukhina S,Zhang G,Tan JSC,Ong HS,Makeyev EV
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Immunofluorescence
Thu Nov 01 00:00:00 EDT 2018
PolyC-binding proteins enhance expression of the CDK2 cell cycle regulatory protein via alternative splicing.
Nucleic acids research
Ji X,Humenik J,Yang D,Liebhaber SA
32-4800 was used in Western Blotting to demonstrate that the binding of PolyC-binding protein at exon 5 of the CDK2 transcript enhances expression by alternative splicing.
Wed Feb 28 00:00:00 EST 2018
The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway.
Stem cell reports
Sun Z,Zhu M,Lv P,Cheng L,Wang Q,Tian P,Yan Z,Wen B
32-4800 was used in Western Blotting to investigate the functional roles of Lncenc1, a highly abundant long noncoding RNA in naive embryonic stem cells.
Tue Sep 11 00:00:00 EDT 2018
The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway.
Stem cell reports
Sun Z,Zhu M,Lv P,Cheng L,Wang Q,Tian P,Yan Z,Wen B
32-4800 was used in Western Blotting to investigate the functional roles of Lncenc1, a highly abundant long noncoding RNA in naive embryonic stem cells.
Tue Sep 11 00:00:00 EDT 2018
The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway.
Stem cell reports
Sun Z,Zhu M,Lv P,Cheng L,Wang Q,Tian P,Yan Z,Wen B
32-4800 was used in Western Blotting to investigate the functional roles of Lncenc1, a highly abundant long noncoding RNA in naive embryonic stem cells.
Tue Sep 11 00:00:00 EDT 2018
Pathogenic variants that alter protein code often disrupt splicing.
Nature genetics
Soemedi R,Cygan KJ,Rhine CL,Wang J,Bulacan C,Yang J,Bayrak-Toydemir P,McDonald J,Fairbrother WG
32-4800 was used in Western Blotting to discover that splicing defects cluster in diseases (e.g. haploinsufficient genes).
Thu Jun 01 00:00:00 EDT 2017
A mechanism underlying position-specific regulation of alternative splicing.
Nucleic acids research
Hamid FM,Makeyev EV
32-4800 was used in Western Blotting to argue that the functional outcome of individual RNA contacts made by an RNA-binding protein is subject to extensive context-specific modulation.
Fri Dec 01 00:00:00 EST 2017
Long noncoding RNA MEG3 induces cholestatic liver injury by interaction with PTBP1 to facilitate shp mRNA decay.
Hepatology (Baltimore, Md.)
Zhang L,Yang Z,Trottier J,Barbier O,Wang L
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Immunoprecipitation
Wed Feb 01 00:00:00 EST 2017
Long noncoding RNA MEG3 induces cholestatic liver injury by interaction with PTBP1 to facilitate shp mRNA decay.
Hepatology (Baltimore, Md.)
Zhang L,Yang Z,Trottier J,Barbier O,Wang L
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Immunoprecipitation
Wed Feb 01 00:00:00 EST 2017
hnRNP I regulates neonatal immune adaptation and prevents colitis and colorectal cancer.
PLoS genetics
Jin Z,Liang F,Yang J,Mei W
324800 was used in western blot to explore the role of heterogeneous nuclear ribonucleoprotein I in regulating neonatal immune adaptation
Wed Mar 01 00:00:00 EST 2017
hnRNP I regulates neonatal immune adaptation and prevents colitis and colorectal cancer.
PLoS genetics
Jin Z,Liang F,Yang J,Mei W
324800 was used in western blot to explore the role of heterogeneous nuclear ribonucleoprotein I in regulating neonatal immune adaptation
Wed Mar 01 00:00:00 EST 2017
The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators.
Nucleic acids research
Llorian M,Gooding C,Bellora N,Hallegger M,Buckroyd A,Wang X,Rajgor D,Kayikci M,Feltham J,Ule J,Eyras E,Smith CW
32-4800 was used in western blot to characterize the involvement of concerted non-productive splicing of post-transcriptional regulators that involves the alternative splicing program of differentiatied smooth muscle cells
Fri Oct 14 00:00:00 EDT 2016
The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators.
Nucleic acids research
Llorian M,Gooding C,Bellora N,Hallegger M,Buckroyd A,Wang X,Rajgor D,Kayikci M,Feltham J,Ule J,Eyras E,Smith CW
32-4800 was used in western blot to characterize the involvement of concerted non-productive splicing of post-transcriptional regulators that involves the alternative splicing program of differentiatied smooth muscle cells
Fri Oct 14 00:00:00 EDT 2016
Human polypyrimidine tract-binding protein interacts with mitochondrial tRNA(Thr) in the cytosol.
Nucleic acids research
Marnef A,Jády BE,Kiss T
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Immunoprecipitation
Thu Feb 18 00:00:00 EST 2016
Human polypyrimidine tract-binding protein interacts with mitochondrial tRNA(Thr) in the cytosol.
Nucleic acids research
Marnef A,Jády BE,Kiss T
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Immunoprecipitation
Thu Feb 18 00:00:00 EST 2016
Human polypyrimidine tract-binding protein interacts with mitochondrial tRNA(Thr) in the cytosol.
Nucleic acids research
Marnef A,Jády BE,Kiss T
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Immunoprecipitation
Thu Feb 18 00:00:00 EST 2016
Characterization of the Regulation of CD46 RNA Alternative Splicing.
The Journal of biological chemistry
Tang SJ,Luo S,Ho JXJ,Ly PT,Goh E,Roca X
324800 was used in western blot to analyze the different isoforms of human CD46
Fri Jul 01 00:00:00 EDT 2016
Methods for the characterization of stress granules in virus infected cells.
Methods (San Diego, Calif.)
Panas MD,Kedersha N,McInerney GM
32-4800 was used in western blot to discuss methods for the characterization of stress granules in virus infected cells
Sun Nov 15 00:00:00 EST 2015
Brain metastasis is predetermined in early stages of cutaneous melanoma by CD44v6 expression through epigenetic regulation of the spliceosome.
Pigment cell & melanoma research
Marzese DM,Liu M,Huynh JL,Hirose H,Donovan NC,Huynh KT,Kiyohara E,Chong K,Cheng D,Tanaka R,Wang J,Morton DL,Barkhoudarian G,Kelly DF,Hoon DS
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Western Blot
Thu Jan 01 00:00:00 EST 2015
ABLIM1 splicing is abnormal in skeletal muscle of patients with DM1 and regulated by MBNL, CELF and PTBP1.
Genes to cells : devoted to molecular & cellular mechanisms
Ohsawa N,Koebis M,Mitsuhashi H,Nishino I,Ishiura S
32-4800 was used in Western Blotting to identify abnormal splicing of actin-binding LIM protein 1 in skeletal muscles of patients with myotonic dystrophy type 1 (DM1) and a DM1 mouse model.
Sun Feb 01 00:00:00 EST 2015
PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus.
Cerebral cortex (New York, N.Y. : 1991)
Shibasaki T,Tokunaga A,Sakamoto R,Sagara H,Noguchi S,Sasaoka T,Yoshida N
Thu Aug 01 00:00:00 EDT 2013
Translation of Myocyte Enhancer Factor-2 is induced by hypertrophic stimuli in cardiomyocytes through a Calcineurin-dependent pathway.
Journal of molecular and cellular cardiology
Ye J,Cardona M,Llovera M,Comella JX,Sanchis D
32-4800 was used in western blot to report that MEF2 protein levels are regulated at the translational level and determine myocyte size during hypertrophy.
Mon Oct 01 00:00:00 EDT 2012
Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing.
PLoS genetics
Pradeepa MM,Sutherland HG,Ule J,Grimes GR,Bickmore WA
32-4800 was used in Chromatin immunoprecipitation to propose that Psip1/p52, through its binding to both chromatin and splicing factors, might act to modulate splicing.
Wed Sep 26 00:00:00 EDT 2012
The leader protein of cardioviruses inhibits stress granule assembly.
Journal of virology
Borghese F,Michiels T
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Immunofluorescence
Thu Sep 01 00:00:00 EDT 2011
Polypyrimidine tract-binding protein 1 regulates the alternative splicing of dopamine receptor D2.
Journal of neurochemistry
Sasabe T,Futai E,Ishiura S
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Western Blot
Sat Jan 01 00:00:00 EST 2011
In vivo regulation of amyloid precursor protein neuronal splicing by microRNAs.
Journal of neurochemistry
Smith P,Al Hashimi A,Girard J,Delay C,Hébert SS
32-4800 was used in western blot to investigate the role of miRNAs in amyloid precursor protein splicing in vivo.
Sat Jan 01 00:00:00 EST 2011
MicroRNA-132 loss is associated with tau exon 10 inclusion in progressive supranuclear palsy.
Human molecular genetics
Smith PY,Delay C,Girard J,Papon MA,Planel E,Sergeant N,Buée L,Hébert SS
32-4800 was used in western blot to study the mechanism for the tau exon mis-splicing in progressive supranuclear palsy.
Sat Oct 15 00:00:00 EDT 2011
PTBP1 is required for embryonic development before gastrulation.
PloS one
Suckale J,Wendling O,Masjkur J,Jäger M,Münster C,Anastassiadis K,Stewart AF,Solimena M
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Immunofluorescence
Thu Feb 17 00:00:00 EST 2011
Polypyrimidine tract-binding protein regulates the cell cycle through IRES-dependent translation of CDK11(p58) in mouse embryonic stem cells.
Cell cycle (Georgetown, Tex.)
Ohno S,Shibayama M,Sato M,Tokunaga A,Yoshida N
32-4800 was used in Western Blotting to suggest that polypyrimidine tract-binding protein regulates the expression of CDK11(p58) through interaction with CDK11(p58) internal ribosome entry site.
Tue Nov 01 00:00:00 EDT 2011
Regulation of alternative splicing by histone modifications.
Science (New York, N.Y.)
Luco RF,Pan Q,Tominaga K,Blencowe BJ,Pereira-Smith OM,Misteli T
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Immunoprecipitation
Fri Feb 19 00:00:00 EST 2010
Cardiovirus leader proteins are functionally interchangeable and have evolved to adapt to virus replication fitness.
The Journal of general virology
Paul S,Michiels T
32-4800 was used in immunocytochemistry to compare viral leader proteins
Mon May 01 00:00:00 EDT 2006
Polypyrimidine tract-binding protein promotes insulin secretory granule biogenesis.
Nature cell biology
Knoch KP,Bergert H,Borgonovo B,Saeger HD,Altkrüger A,Verkade P,Solimena M
Mon Mar 01 00:00:00 EST 2004
The leader protein of Theiler's virus interferes with nucleocytoplasmic trafficking of cellular proteins.
Journal of virology
Delhaye S,van Pesch V,Michiels T
Published figure using PTBP1 monoclonal antibody (Product # 32-4800) in Immunofluorescence
Thu Apr 01 00:00:00 EST 2004
Alteration of cellular RNA splicing and polyadenylation machineries during productive human cytomegalovirus infection.
The Journal of general virology
Adair R,Liebisch GW,Su Y,Colberg-Poley AM
32-4800 was used in western blot to study human cytomegalovirus UL37 isoforms
Wed Dec 01 00:00:00 EST 2004
