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Product Details
11512-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PUS1 Fusion Protein Ag2071 (128-427 aa encoded by BC019320)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ENHGEDMRK MSFQRCARTD KGVSAAGQVV SLKVWLIDDI LEKINSHLPS HIRILGLKRV TGGFNSKNRC DARTYCYLLP TFAFAHKDRD VQDETYRLSA ETLQQVNRLL ACYKGTHNFH NFTSQKGPQD PSACRYILEM YCEEPFVREG LEFAVIRVKG QSFMMHQIRK MVGLVVAIVK GYAPESVLER SWGTEKVDVP KAPGLGLVLE RVHFEKYNQR FGNDGLHEPL DWAQEEGKVA AFKEEHIYPT IIGTERDERS MAQWLSTLPI HNFSATALTA GGTGAKVPSP LEGSEGDGDT D (128-427 aa encoded by BC019320)
Target Information
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku, which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: mitochondrial tRNA pseudouridine synthase A; pseudouridine synthase 1; Pseudouridylate synthase 1 homolog; pus1 {ECO:0000312|RGD:1311871}; tRNA pseudouridine synthase 1; tRNA pseudouridine synthase A, mitochondrial; tRNA pseudouridine(38-40) synthase; tRNA pseudouridylate synthase I; tRNA uridine isomerase I; tRNA-uridine isomerase I
Gene Aliases: A730013B20Rik; MLASA1; MNCb-0873; MPUS1; mPus1p; PP8985; PUS1
UniProt ID: (Human) Q9Y606, (Rat) Q4KM92, (Mouse) Q9WU56
Entrez Gene ID: (Human) 80324, (Rat) 304567, (Mouse) 56361
pseudouridylate synthase activity
pseudouridine synthase activity
poly(A) RNA binding
ligand-dependent nuclear receptor transcription coactivator activity
RNA binding
protein binding
isomerase activity
pivalyl-CoA mutase activity
o-hydroxylaminobenzoate mutase activity
lupeol synthase activity
beta-amyrin synthase activity
baruol synthase activity
lyase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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