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Phospho-BIK (Thr33) Antibody (PA5-104246) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-BIK (Thr33) in human Thyroid cancer tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-BIK (Thr33) polyclonal antibody (Product # PA5-104246) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Product Details
PA5-104246
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human BIK(Accession Q13323), corresponding to amino acid residues around phosphorylated Thr33.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2816008
Product Specific Information
Antibody detects endogenous levels of BIK only when phosphorylated at Threonine 33.
Target Information
The Bik protein is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programmed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apoptosis inducer NBK; apoptosis-inducing NBK; BBC1; Bcl-2-interacting killer; BCL2-interacting killer (apoptosis-inducing); bhikhari; BIP 1; BIP1; BP 4; BP4; cb 60; natural born killer
Gene Aliases: BIK; BIP1; BP4; NBK
UniProt ID: (Human) Q13323
Entrez Gene ID: (Human) 638
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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