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7TM Antibodies
Phospho-CXC Chemokine Receptor 6 (Ser329, Ser331) Polyclonal Antibody
FIGURE: 1 / 2
Phospho-CXC Chemokine Receptor 6 (Ser329, Ser331) Antibody (7TM0073C) in WB
Analysis of dose-dependent CXC Chemokine Receptor 6 phosphorylation using three phosphosite-specific antibodies. Upper two panels, HEK293 cells stably expressing the CXC Chemokine Receptor 6 (CXCR6) were either not exposed or exposed to increasing concentrations of CXCL16 ranging from 3 nM to 100 nM for 30 minutes. Cells were lysed and immunoblotted with the anti-pS320/pS321-CXCR6 antibody (7TM0073A) or ant... View More
Product Details
7TM0073C
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic phosphopeptide derived from human CXCR6 around the phosphorylation site of Ser329/Ser331.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
Dulbecco's PBS, pH 7.4
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
CD186, also known as CXCR6, is a G protein-coupled chemokine receptor reported to be one of the cellular receptors of HIV and SIV. CD186 is expressed by NKT cells, various subtypes of T cells with activated and memory phenotypes, and some plasma cells. It has been reported that mouse liver NK cells, but not naïve or splenic NK cells, express CD186. The ligand of CD186, CXCL16, is expressed by macrophages, dendritic cells and liver endothelial cells. Being highly expressed on NKT cells, CD186 is often used as a proxy marker of this cell subset.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C chemokine receptor type 6; CC motif chemokine; CCmotif chemokine; CD186; CD186 antigen; CDw186; chemokine (C-X-C motif) receptor 6; CXC; CXC motif chemokine; CXC-R6; CXCR-6; G protein-coupled receptor; G-protein coupled receptor bonzo; G-protein coupled receptor STRL33; OTTHUMP00000209997; OTTHUMP00000209998
Gene Aliases: BONZO; CD186; CXCR6; STRL33; TYMSTR
UniProt ID: (Human) O00574
Entrez Gene ID: (Human) 10663
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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