Product References
Phosphorylation of GluA1-Ser831 by CaMKII Activation in the Caudate and Putamen Is Required for Behavioral Sensitization After Challenge Nicotine in Rats.
The international journal of neuropsychopharmacology
Kim S,Sohn S,Choe ES
MA1-047 was used in Western Blotting to suggest that the GluA1-Ser831 phosphorylation in the MSNs of the CPu is required for the challenge nicotine-induced behavioral sensitization in rats.
Tue Aug 16 00:00:00 EDT 2022
Phospho-ablation of cardiac sodium channel Nav1.5 mitigates susceptibility to atrial fibrillation and improves glucose homeostasis under conditions of diet-induced obesity.
International journal of obesity (2005)
Dewal RS,Greer-Short A,Lane C,Nirengi S,Manzano PA,Hernández-Saavedra D,Wright KR,Nassal D,Baer LA,Mohler PJ,Hund TJ,Stanford KI
MA1-047 was used in Western Blot to investigate the role for CaMKII-dependent INa,L in obesity-induced atrial fibrillation using wild-type (WT) and whole-body knock-in mice that ablates phosphorylation of the Nav1.5 sodium channel and prevents augmentation of the late sodium current (S571A; SA mice).
Thu Apr 01 00:00:00 EDT 2021
Cell-to-cell diversification in ERBB-RAS-MAPK signal transduction that produces cell-type specific growth factor responses.
Bio Systems
Miyagi H,Hiroshima M,Sako Y
MA1-047 was used in Immunocytochemistry-immunoflourescence to detect the phosphorylation of seven elements in the early response of the ERBB-RAS-MAPK system to two growth factors.
Fri Jan 01 00:00:00 EST 2021
Cellular Mechanisms of the Anti-Arrhythmic Effect of Cardiac PDE2 Overexpression.
International journal of molecular sciences
Wagner M,Sadek MS,Dybkova N,Mason FE,Klehr J,Firneburg R,Cachorro E,Richter K,Klapproth E,Kuenzel SR,Lorenz K,Heijman J,Dobrev D,El-Armouche A,Sossalla S,Kämmerer S
Published figure using Phospho-CaMKII alpha (Thr286) monoclonal antibody (Product # MA1-047) in Western Blot
Sat May 01 00:00:00 EDT 2021
Voltage-independent GluN2A-type NMDA receptor Ca2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice.
Communications biology
Bertocchi I,Eltokhi A,Rozov A,Chi VN,Jensen V,Bus T,Pawlak V,Serafino M,Sonntag H,Yang B,Burnashev N,Li SB,Obenhaus HA,Both M,Niewoehner B,Single FN,Briese M,Boerner T,Gass P,Rawlins JNP,Köhr G,Bannerman DM,Sprengel R
MA1-047 was used in Western Blotting to provide (i) experimental evidence that the inherent voltage-dependent Ca2+ signaling of NMDA receptors is essential for maintaining appropriate responses to sensory stimuli and (ii) a mechanistic explanation for the neurological manifestations seen in the NMDAR-related human disorders with GRIN2 variant-meidiated intellectual disability and focal epilepsy.
Fri Jan 08 00:00:00 EST 2021
Voltage-independent GluN2A-type NMDA receptor Ca2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice.
Communications biology
Bertocchi I,Eltokhi A,Rozov A,Chi VN,Jensen V,Bus T,Pawlak V,Serafino M,Sonntag H,Yang B,Burnashev N,Li SB,Obenhaus HA,Both M,Niewoehner B,Single FN,Briese M,Boerner T,Gass P,Rawlins JNP,Köhr G,Bannerman DM,Sprengel R
MA1-047 was used in Western Blotting to provide (i) experimental evidence that the inherent voltage-dependent Ca2+ signaling of NMDA receptors is essential for maintaining appropriate responses to sensory stimuli and (ii) a mechanistic explanation for the neurological manifestations seen in the NMDAR-related human disorders with GRIN2 variant-meidiated intellectual disability and focal epilepsy.
Fri Jan 08 00:00:00 EST 2021
Loss of CASK Accelerates Heart Failure Development.
Circulation research
Mustroph J,Sag CM,Bähr F,Schmidtmann AL,Gupta SN,Dietz A,Islam MMT,Lücht C,Beuthner BE,Pabel S,Baier MJ,El-Armouche A,Sossalla S,Anderson ME,Möllmann J,Lehrke M,Marx N,Mohler PJ,Bers DM,Unsöld B,He T,Dewenter M,Backs J,Maier LS,Wagner S
MA1-047 was used in ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot to suggest that loss of CASK accelerates heart failure development.
Fri Apr 16 00:00:00 EDT 2021
A gap-junction-mediated, calcium-signaling network controls blood progenitor fate decisions in hematopoiesis.
Current biology : CB
Ho KYL,Khadilkar RJ,Carr RL,Tanentzapf G
MA1-047 was used in Immunohistochemistry-immunofluorescence to investigate progenitor fate decisions in hematopoiesis.
Mon Nov 08 00:00:00 EST 2021
Cyclin-dependent-like kinase 5 is required for pain signaling in human sensory neurons and mouse models.
Science translational medicine
La Montanara P,Hervera A,Baltussen LL,Hutson TH,Palmisano I,De Virgiliis F,Kong G,Chadwick J,Gao Y,Bartus K,Majid QA,Gorgoraptis N,Wong K,Downs J,Pizzorusso T,Ultanir SK,Leonard H,Yu H,Millar DS,Istvan N,Mazarakis ND,Di Giovanni S
MA1-047 was used in Immunohistochemistry to unveil a previously unrecognized role for CDKL5 in nociception, proposing an original regulatory mechanism for pain perception with implications for future therapeutics in CDKL5 deficiency disorder.
Wed Jul 08 00:00:00 EDT 2020
Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy.
EMBO molecular medicine
Bella P,Farini A,Banfi S,Parolini D,Tonna N,Meregalli M,Belicchi M,Erratico S,D'Ursi P,Bianco F,Legato M,Ruocco C,Sitzia C,Sangiorgi S,Villa C,D'Antona G,Milanesi L,Nisoli E,Mauri P,Torrente Y
MA1-047 was used in Western Blotting to demonstrate that the type 2 IGF receptor (IGF2R) and the store-operated Ca2+ channel CD20 share a common hydrophobic binding motif that stabilizes their association.
Thu Jan 09 00:00:00 EST 2020
Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy.
EMBO molecular medicine
Bella P,Farini A,Banfi S,Parolini D,Tonna N,Meregalli M,Belicchi M,Erratico S,D'Ursi P,Bianco F,Legato M,Ruocco C,Sitzia C,Sangiorgi S,Villa C,D'Antona G,Milanesi L,Nisoli E,Mauri P,Torrente Y
MA1-047 was used in Western Blotting to demonstrate that the type 2 IGF receptor (IGF2R) and the store-operated Ca2+ channel CD20 share a common hydrophobic binding motif that stabilizes their association.
Thu Jan 09 00:00:00 EST 2020
A Sam68-dependent alternative splicing program shapes postsynaptic protein complexes.
The European journal of neuroscience
Witte H,Schreiner D,Scheiffele P
MA1-047 was used in Western Blot to suggest an important role for Sam68-dependent alternative splicing in the regulation of synapses in the central nervous system.
Sat Jun 01 00:00:00 EDT 2019
Cul3 and insomniac are required for rapid ubiquitination of postsynaptic targets and retrograde homeostatic signaling.
Nature communications
Kikuma K,Li X,Perry S,Li Q,Goel P,Chen C,Kim D,Stavropoulos N,Dickman D
MA1-047 was used in Immunocytochemistry to suggest that Cul3/Inc-dependent mono-ubiquitination, compartmentalized at postsynaptic densities, gates retrograde signaling and provides an intriguing molecular link between the control of sleep and homeostatic plasticity at synapses.
Fri Jul 05 00:00:00 EDT 2019
Effects of hypoestrogenism and/or hyperaldosteronism on myocardial remodeling in female mice.
Physiological reports
Rouet-Benzineb P,Merval R,Polidano E
Published figure using Phospho-CaMKII alpha (Thr286) monoclonal antibody (Product # MA1-047) in Western Blot
Thu Nov 01 00:00:00 EDT 2018
CaMKII Potentiates Store-Operated Ca2+ Entry Through Enhancing STIM1 Aggregation and Interaction with Orai1.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Li S,Xue J,Sun Z,Liu T,Zhang L,Wang L,You H,Fan Z,Zheng Y,Luo D
MA1-047 was used in Western blotting following immunoprecipitation to evaluate stromal interaction molecule 1 aggregation and its interaction with Ca2+ selective channel-forming subunit, and store-operated Ca2+ entry upon Ca2+ store depletion in thapsigargin treated HEK293 and HeLa cells.
Thu Jul 05 00:00:00 EDT 2018
Arrhythmias precede cardiomyopathy and remodeling of Ca2+ handling proteins in a novel model of long QT syndrome.
Journal of molecular and cellular cardiology
Montnach J,Chizelle FF,Belbachir N,Castro C,Li L,Loussouarn G,Toumaniantz G,Carcouët A,Meinzinger AJ,Shmerling D,Benitah JP,Gómez AM,Charpentier F,Baró I
MA1-047 was used in Western Blotting to show that the Scn5a+/ΔQKP mouse model recapitulates the clinical phenotype of mutation carriers and provides new and unexpected insights into the pathological development of the disease in patients carrying the QKP1507-1509 deletion.
Mon Oct 01 00:00:00 EDT 2018
Synapse-specific and compartmentalized expression of presynaptic homeostatic potentiation.
eLife
Li X,Goel P,Chen C,Angajala V,Chen X,Dickman DK
MA1-047 was used in Immunocytochemistry to show that PHP induction and expression mechanisms are locally transmitted and restricted to specific synaptic compartments.
Thu Apr 05 00:00:00 EDT 2018
Primary Effect of SERCA 2a Gene Transfer on Conduction Reserve in Chronic Myocardial Infarction.
Journal of the American Heart Association
Motloch LJ,Cacheux M,Ishikawa K,Xie C,Hu J,Aguero J,Fish KM,Hajjar RJ,Akar FG
MA1-047 was used in Western Blotting to study the electrophysiological effects of adeno-associated virus serotype 1 SERCA 2a gene transfer following myocardial infarction.
Tue Sep 18 00:00:00 EDT 2018
Cardiomyocyte proliferation prevents failure in pressure overload but not volume overload.
The Journal of clinical investigation
Toischer K,Zhu W,Hünlich M,Mohamed BA,Khadjeh S,Reuter SP,Schäfer K,Ramanujam D,Engelhardt S,Field LJ,Hasenfuss G
MA1-047 was used in Western Blotting to study whether enhanced cardiomyocyte renewal in transgenic mice expressing cyclin D2 is beneficial during haemodynamic overload.
Fri Dec 01 00:00:00 EST 2017
The amyloid-β oligomer Aβ*56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation.
Science signaling
Amar F,Sherman MA,Rush T,Larson M,Boyle G,Chang L,Götz J,Buisson A,Lesné SE
MA1-047 was used in Immunoprecipitation to find that Amyloid-Β*56, is detected before patients develop overt signs of Alzheimer's disease and induces specific changes in neuronal signalling.
Tue May 09 00:00:00 EDT 2017
Activity-dependent expression of Channelrhodopsin at neuronal synapses.
Nature communications
Gobbo F,Marchetti L,Jacob A,Pinto B,Binini N,Pecoraro Bisogni F,Alia C,Luin S,Caleo M,Fellin T,Cancedda L,Cattaneo A
Published figure using Phospho-CaMKII alpha (Thr286) monoclonal antibody (Product # MA1-047) in Immunofluorescence
Mon Nov 20 00:00:00 EST 2017
Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm.
Nature communications
Cerrone M,Montnach J,Lin X,Zhao YT,Zhang M,Agullo-Pascual E,Leo-Macias A,Alvarado FJ,Dolgalev I,Karathanos TV,Malkani K,Van Opbergen CJM,van Bavel JJA,Yang HQ,Vasquez C,Tester D,Fowler S,Liang F,Rothenberg E,Heguy A,Morley GE,Coetzee WA,Trayanova NA,Ackerman MJ,van Veen TAB,Valdivia HH,Delmar M
MA1-047 was used in Immunohistochemistry to show that PKP2 controls the expression of proteins involved in calcium cycling in adult mouse hearts, and that lack of PKP2 can cause arrhythmia in a structurally normal heart.
Mon Jul 24 00:00:00 EDT 2017
Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure.
Circulation research
Sanchez-Alonso JL,Bhargava A,O'Hara T,Glukhov AV,Schobesberger S,Bhogal N,Sikkel MB,Mansfield C,Korchev YE,Lyon AR,Punjabi PP,Nikolaev VO,Trayanova NA,Gorelik J
MA1047 was used in western blot to discuss how disruption in subcellular targeting of calcium signaling contributes to heart disease
Fri Sep 30 00:00:00 EDT 2016
Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure.
Circulation research
Sanchez-Alonso JL,Bhargava A,O'Hara T,Glukhov AV,Schobesberger S,Bhogal N,Sikkel MB,Mansfield C,Korchev YE,Lyon AR,Punjabi PP,Nikolaev VO,Trayanova NA,Gorelik J
MA1047 was used in western blot to discuss how disruption in subcellular targeting of calcium signaling contributes to heart disease
Fri Sep 30 00:00:00 EDT 2016
Inositol 1,4,5-trisphosphate (IP3)-dependent Ca2+ signaling mediates delayed myogenesis in Duchenne muscular dystrophy fetal muscle.
Development (Cambridge, England)
Farini A,Sitzia C,Cassinelli L,Colleoni F,Parolini D,Giovanella U,Maciotta S,Colombo A,Meregalli M,Torrente Y
MA1-047 was used in western blot to analyze mediation of delayed myogenesis in Duchenne muscular dystrophy fetal muscle by inositol 1,4,5-triphosphate (IP3)-dependent Ca2+ signaling
Mon Feb 15 00:00:00 EST 2016
CaMKII-dependent myofilament Ca2+ desensitization contributes to the frequency-dependent acceleration of relaxation.
Cell calcium
Guilbert A,Lim HJ,Cheng J,Wang Y
MA1-047 was used in western blot to investigate CaMKII-dependent regulation of myofilament calcium sensitivity
Sun Nov 01 00:00:00 EDT 2015
Differential CaMKII regulation by voltage-gated calcium channels in the striatum.
Molecular and cellular neurosciences
Pasek JG,Wang X,Colbran RJ
MA1-047 was used in western blot to investigate the regulatory effect of voltage-gated calcium channels on CaMKII in the striatum
Tue Sep 01 00:00:00 EDT 2015
Long-term administration of the TNF blocking drug Remicade (cV1q) to mdx mice reduces skeletal and cardiac muscle fibrosis, but negatively impacts cardiac function.
Neuromuscular disorders : NMD
Ermolova NV,Martinez L,Vetrone SA,Jordan MC,Roos KP,Sweeney HL,Spencer MJ
MA1-047 was used in western blot to study the reduced levels of skeletal and cardiac muscle fibrosis but impaired cardiac function in mdx mice following long-term treatment with the TNF-alpha blocking agent Remicade
Tue Jul 01 00:00:00 EDT 2014
Gender-specific potential inhibitory role of Ca2+/calmodulin dependent protein kinase phosphatase (CaMKP) in pressure-overloaded mouse heart.
PloS one
Prévilon M,Pezet M,Vinet L,Mercadier JJ,Rouet-Benzineb P
MA1-047 was used in immunohistochemistry to study gender differences in the effects of CaMKP on the CaMKII-MEK2 signaling pathway in a murine model of left ventricular hypertrophy
Thu Feb 12 00:00:00 EST 2015
Gender-specific potential inhibitory role of Ca2+/calmodulin dependent protein kinase phosphatase (CaMKP) in pressure-overloaded mouse heart.
PloS one
Prévilon M,Pezet M,Vinet L,Mercadier JJ,Rouet-Benzineb P
MA1-047 was used in immunohistochemistry to study gender differences in the effects of CaMKP on the CaMKII-MEK2 signaling pathway in a murine model of left ventricular hypertrophy
Thu Feb 12 00:00:00 EST 2015
Chronic caffeine treatment prevents stress-induced LTP impairment: the critical role of phosphorylated CaMKII and BDNF.
Journal of molecular neuroscience : MN
Alzoubi KH,Srivareerat M,Aleisa AM,Alkadhi KA
MA1-047 was used in western blot to study the role of BDNF and CaMKII in the prevention of chronic stress-induced impairment of LTP by caffeine
Tue Jan 01 00:00:00 EST 2013
The effects of neuregulin on cardiac Myosin light chain kinase gene-ablated hearts.
PloS one
Chang AN,Huang J,Battiprolu PK,Hill JA,Kamm KE,Stull JT
MA1-047 was used in western blot to study the cardiac effects of neuregulin in cMLCK knockout mice
Thu Jan 16 00:00:00 EST 2014
7,8-dihydroxyflavone rescues spatial memory and synaptic plasticity in cognitively impaired aged rats.
Journal of neurochemistry
Zeng Y,Lv F,Li L,Yu H,Dong M,Fu Q
MA1-047 was used in western blot to study the improvement in spacial memory and synaptic plasticity of rats suffering age-related cognitive dysfunction following treatment with 7,8-dihydroxyflavone
Wed Aug 01 00:00:00 EDT 2012
The effects of oral taurine administration on behavior and hippocampal signal transduction in rats.
Amino acids
Iio W,Matsukawa N,Tsukahara T,Toyoda A
MA1-047 was used in western blot to study the effects of taurine on antidepressive behaviour and depression-related signaling in the rat hippocampus
Thu Nov 01 00:00:00 EDT 2012
Deletion of densin-180 results in abnormal behaviors associated with mental illness and reduces mGluR5 and DISC1 in the postsynaptic density fraction.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Carlisle HJ,Luong TN,Medina-Marino A,Schenker L,Khorosheva E,Indersmitten T,Gunapala KM,Steele AD,O'Dell TJ,Patterson PH,Kennedy MB
MA1-047 was used in western blot to investigate the role of densin-180 in the organization and dynamics of postsynaptic signaling complexes
Wed Nov 09 00:00:00 EST 2011
SR-targeted CaMKII inhibition improves SR Ca²+ handling, but accelerates cardiac remodeling in mice overexpressing CaMKIIδC.
Journal of molecular and cellular cardiology
Huke S,Desantiago J,Kaetzel MA,Mishra S,Brown JH,Dedman JR,Bers DM
MA1-047 was used in western blot to study the role of CaMKII inhibition in calcium homeostasis and cardiac hypertrophy
Sat Jan 01 00:00:00 EST 2011
CaMKII-dependent SR Ca leak contributes to doxorubicin-induced impaired Ca handling in isolated cardiac myocytes.
Journal of molecular and cellular cardiology
Sag CM,Köhler AC,Anderson ME,Backs J,Maier LS
MA1-047 was used in western blot to study the role of calcium leakage in Doxorubicin-based cardiotoxicity
Tue Nov 01 00:00:00 EDT 2011
Abnormalities in α/β-CaMKII and related mechanisms suggest synaptic dysfunction in hippocampus of LPA1 receptor knockout mice.
The international journal of neuropsychopharmacology
Musazzi L,Di Daniel E,Maycox P,Racagni G,Popoli M
MA1-047 was used in western blot to investigate the role of lysophosphatidic acid receptor in synaptic formation and functions
Mon Aug 01 00:00:00 EDT 2011
AMPA GluR-A receptor subunit mediates hippocampal responsiveness in mice exposed to stress.
Hippocampus
Fumagalli F,Caffino L,Vogt MA,Frasca A,Racagni G,Sprengel R,Gass P,Riva MA
MA1-047 was used in western blot to investigate the involvement of specific AMPA receptor in the stress-stimulated hippocampal response in mice
Thu Sep 01 00:00:00 EDT 2011
PCP4 (PEP19) overexpression induces premature neuronal differentiation associated with Ca(2+) /calmodulin-dependent kinase II-δ activation in mouse models of Down syndrome.
The Journal of comparative neurology
Mouton-Liger F,Thomas S,Rattenbach R,Magnol L,Larigaldie V,Ledru A,Herault Y,Verney C,Créau N
Published figure using Phospho-CaMKII alpha (Thr286) monoclonal antibody (Product # MA1-047) in Immunocytochemistry
Sat Oct 01 00:00:00 EDT 2011
FKBP12.6 mice display temporal gender differences in cardiac Ca(2+)-signalling phenotype upon chronic pressure overload.
Canadian journal of physiology and pharmacology
Prévilon M,Pezet M,Semprez F,Mercadier JJ,Rouet-Benzineb P
MA1-047 was used in western blot to investigate the role of FKBP12.6 in the cardiac calcium homeostasis and in the pathogenesis of heart failure
Tue Nov 01 00:00:00 EDT 2011
CaMKII-dependent diastolic SR Ca2+ leak and elevated diastolic Ca2+ levels in right atrial myocardium of patients with atrial fibrillation.
Circulation research
Neef S,Dybkova N,Sossalla S,Ort KR,Fluschnik N,Neumann K,Seipelt R,Schöndube FA,Hasenfuss G,Maier LS
MA1-047 was used in western blot to investigate the effect of CaMKII overexpression on sarcoplasmic reticulum calcium leak and diastolic calcium level in atrial fibrillation
Fri Apr 02 00:00:00 EDT 2010
Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice.
Circulation research
Zhang T,Guo T,Mishra S,Dalton ND,Kranias EG,Peterson KL,Bers DM,Brown JH
MA1-047 was used in western blot to investigate the effect of phospholamban blockade on heart function in transgenic mice
Fri Feb 05 00:00:00 EST 2010
Ca2+-dependent facilitation of Cav1.3 Ca2+ channels by densin and Ca2+/calmodulin-dependent protein kinase II.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Jenkins MA,Christel CJ,Jiao Y,Abiria S,Kim KY,Usachev YM,Obermair GJ,Colbran RJ,Lee A
MA1-047 was used in western blot to investigate the involvement of densin in CaMKII-mediated Cav1.3 modulation
Wed Apr 14 00:00:00 EDT 2010
CaMKII associates with CaV1.2 L-type calcium channels via selected beta subunits to enhance regulatory phosphorylation.
Journal of neurochemistry
Abiria SA,Colbran RJ
MA1-047 was used in western blot to demonstrate the role of CaMKII in calcium channel activity
Fri Jan 01 00:00:00 EST 2010
GABA synthesis in Schwann cells is induced by the neuroactive steroid allopregnanolone.
Journal of neurochemistry
Magnaghi V,Parducz A,Frasca A,Ballabio M,Procacci P,Racagni G,Bonanno G,Fumagalli F
MA1-047 was used in western blot to study the effect of neuroactive steroid allopregnanolone on GABA synthesis in Schwann cells
Mon Feb 01 00:00:00 EST 2010
Mitochondria-produced superoxide mediates angiotensin II-induced inhibition of neuronal potassium current.
American journal of physiology. Cell physiology
Yin JX,Yang RF,Li S,Renshaw AO,Li YL,Schultz HD,Zimmerman MC
MA1-047 was used in western blot to investigate the mechanism for the inhibition of neuronal potassium current by angiotensin II
Thu Apr 01 00:00:00 EDT 2010
Early-life stress and antidepressant treatment involve synaptic signaling and Erk kinases in a gene-environment model of depression.
Journal of psychiatric research
Musazzi L,Mallei A,Tardito D,Gruber SH,El Khoury A,Racagni G,Mathé AA,Popoli M
MA1-047 was used in western blot to study role of synaptic signaling and stress in response to treatment for depression
Tue Jun 01 00:00:00 EDT 2010
In vivo expression of ganglionic long-term potentiation in superior cervical ganglia from hypertensive aged rats.
Neurobiology of aging
Alzoubi KH,Aleisa AM,Alkadhi KA
MA1-047 was used in western blot to investigate the induction of ganglionic long-term potentiation in hypertensive aged rats
Sat May 01 00:00:00 EDT 2010
Activation of calcium/calmodulin-dependent protein kinase IIalpha in the striatum by the heteromeric D1-D2 dopamine receptor complex.
Neuroscience
Ng J,Rashid AJ,So CH,O'Dowd BF,George SR
MA1-047 was used in western blot to study the role of dopamine in synaptic plasticity
Wed Jan 20 00:00:00 EST 2010
The dopamine D1-D2 receptor heteromer localizes in dynorphin/enkephalin neurons: increased high affinity state following amphetamine and in schizophrenia.
The Journal of biological chemistry
Perreault ML,Hasbi A,Alijaniaram M,Fan T,Varghese G,Fletcher PJ,Seeman P,O'Dowd BF,George SR
MA1-047 was used in western blot to study the localization of dopamine D1-D2 receptor heteromer localizes in dynorphin/enkephalin neurons
Fri Nov 19 00:00:00 EST 2010
The role of growth retardation in lasting effects of neonatal dexamethasone treatment on hippocampal synaptic function.
PloS one
Wang YC,Huang CC,Hsu KS
MA1-047 was used in western blot to study the role of growth retardation plays in the effects of neonatal dexamethasone on hippocampal function.
Tue Sep 21 00:00:00 EDT 2010
Effect of chronic stress or nicotine on hypothyroidism-induced enhancement of LTD: electrophysiological and molecular studies.
Neurobiology of disease
Alzoubi KH,Aleisa AM,Alkadhi KA
MA1-047 was used in western blot to study the roles of chronic stress or nicotine on hypothyroidism-induced enhancement of LTD
Wed Oct 01 00:00:00 EDT 2008
Expression of gLTP in sympathetic ganglia from stress-hypertensive rats: molecular evidence.
Journal of molecular neuroscience : MN
Alzoubi KH,Aleisa AM,Alkadhi KA
MA1-047 was used in western blot to study gLTP expression in sympathetic ganglia of rats with stress-hypertension
Sun Jun 01 00:00:00 EDT 2008
Detailed state model of CaMKII activation and autophosphorylation.
European biophysics journal : EBJ
Lucić V,Greif GJ,Kennedy MB
MA1-047 was used in western blot to investigate the mechanism for CaMKII activation and autophosphorylation
Sat Nov 01 00:00:00 EDT 2008
Interactions between the NR2B receptor and CaMKII modulate synaptic plasticity and spatial learning.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Zhou Y,Takahashi E,Li W,Halt A,Wiltgen B,Ehninger D,Li GD,Hell JW,Kennedy MB,Silva AJ
MA1-047 was used in western blot to study the role of NR2B receptor-CaMKII interactions in the modulation of synaptic plasticity and spatial learning
Wed Dec 12 00:00:00 EST 2007
Long-term reduction of brain-derived neurotrophic factor levels and signaling impairment following prenatal treatment with the cannabinoid receptor 1 receptor agonist (R)-(+)-[2,3-dihydro-5-methyl-3-(4-morpholinyl-methyl) pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1- naphthalenylmethanone.
The European journal of neuroscience
Maj PF,Collu M,Fadda P,Cattaneo A,Racagni G,Riva MA
MA1-047 was used in western blot to study the effect of prenatal treatment with a cannabinoid receptor 1 receptor agonist on BDNF levels and signaling impairment
Fri Jun 01 00:00:00 EDT 2007
Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling.
The Journal of clinical investigation
Wu X,Zhang T,Bossuyt J,Li X,McKinsey TA,Dedman JR,Olson EN,Chen J,Brown JH,Bers DM
MA1-047 was used in western blot to study the role of calmodulin and calcium/calmodulin dependent protein kinase II in cardiac hypertrophic signaling.
Wed Mar 01 00:00:00 EST 2006
Ca2+/calmodulin-dependent protein kinase II (CaMKII) is activated by calmodulin with two bound calciums.
Proceedings of the National Academy of Sciences of the United States of America
Shifman JM,Choi MH,Mihalas S,Mayo SL,Kennedy MB
MA1-047 was used in western blot to study the activation of calcium/calmodulin-dependent protein kinase II by calcium ions.
Tue Sep 19 00:00:00 EDT 2006
Chronic psychosocial stress-induced impairment of hippocampal LTP: possible role of BDNF.
Neurobiology of disease
Aleisa AM,Alzoubi KH,Gerges NZ,Alkadhi KA
MA1-047 was used in western blot to study the potential role of BDNF in chronic psychosocial stress-induced impairment of hippocampal LTP
Thu Jun 01 00:00:00 EDT 2006
Nicotine prevents stress-induced enhancement of long-term depression in hippocampal area CA1: electrophysiological and molecular studies.
Journal of neuroscience research
Aleisa AM,Alzoubi KH,Alkadhi KA
MA1-047 was used in western blot to study the role of nicotine treatment on long-term depression in the hippocampal area CA1 in chronically stressed rats
Wed Feb 01 00:00:00 EST 2006
Molecular studies on the protective effect of nicotine in adult-onset hypothyroidism-induced impairment of long-term potentiation.
Hippocampus
Alzoubi KH,Aleisa AM,Alkadhi KA
MA1-047 was used in western blot to study the protective effect of nicotine in adult-onset hypothyroidism-induced impairment of long-term potentiation
Mon Dec 04 00:00:00 EST 2006
Calmodulin kinase II regulates the maturation and antigen presentation of human dendritic cells.
Journal of leukocyte biology
Herrmann TL,Morita CT,Lee K,Kusner DJ
MA1-047 was used in immunocytochemistry to investigate the role of calmodulin kinase II (CamK II) for the maturation and antigen presentation of human dendritic cells
Thu Dec 01 00:00:00 EST 2005
Role of phosphorylated CaMKII and calcineurin in the differential effect of hypothyroidism on LTP of CA1 and dentate gyrus.
Hippocampus
Gerges NZ,Alzoubi KH,Alkadhi KA
MA1-047 was used in western blot to study the role of CaMKII and calcineurin phosphorylation in LTP in hypothyroid rats
Thu Aug 11 00:00:00 EDT 2005
Impairment of long-term potentiation in the CA1, but not dentate gyrus, of the hippocampus in Obese Zucker rats: role of calcineurin and phosphorylated CaMKII.
Journal of molecular neuroscience : MN
Alzoubi KH,Aleisa AM,Alkadhi KA
MA1-047 was used in western blot to study the differential impairment of long-term potentiation in the CA1 but not the dentate gyrus region of the hippocampus in obese Zucker rats
Mon Feb 06 00:00:00 EST 2006
Ca2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor.
Circulation research
Wehrens XH,Lehnart SE,Reiken SR,Marks AR
MA1-047 was used in western blot to demonstrate that CaMKII phosphorylation could regulate the cardiac ryanodine receptor and increase RyR2 calcium sensitivity
Fri Apr 02 00:00:00 EST 2004
Ca2+/calmodulin-dependent protein kinase II potentiates ATP responses by promoting trafficking of P2X receptors.
Proceedings of the National Academy of Sciences of the United States of America
Xu GY,Huang LY
MA1-047 was used in western blot to study the role of calcium/calmodulin-dependent protein kinase II in the P2X receptor-mediated ATP responses.
Tue Aug 10 00:00:00 EDT 2004
Cytoplasmic polyadenylation element binding protein-dependent protein synthesis is regulated by calcium/calmodulin-dependent protein kinase II.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Atkins CM,Nozaki N,Shigeri Y,Soderling TR
MA1-047 was used in western blot to study the CPEB phosphorylation by LTP-activated CaMKII, CaMKIV, PKA, and protein kinase C .
Wed Jun 02 00:00:00 EDT 2004
Reduced basal CaMKII levels in hippocampal CA1 region: possible cause of stress-induced impairment of LTP in chronically stressed rats.
Hippocampus
Gerges NZ,Aleisa AM,Schwarz LA,Alkadhi KA
MA1-047 was used in western blot to study the role of reduced basal CaMKII in the impairment of early long term potentiation by stress
Tue Jul 06 00:00:00 EDT 2004
Brief seizure activity alters Ca2+/calmodulin dependent protein kinase II dephosphorylation and subcellular distribution in rat brain for several hours.
Neuroscience letters
Dong Y,Rosenberg HC
MA1-047 was used in western blot to investigate the effect of brief seizure activity on calcium/calmodulin dependent protein kinase II dephosphorylation and subcellular distribution in rat brain
Thu Mar 04 00:00:00 EST 2004
Prolonged changes in Ca2+/calmodulin-dependent protein kinase II after a brief pentylenetetrazol seizure; potential role in kindling.
Epilepsy research
Dong Y,Rosenberg HC
MA1-047 was used in western blot to investigate the role CaMKII in PTZ kindling
Sun Feb 01 00:00:00 EST 2004
Calcium activation of ERK mediated by calmodulin kinase I.
The Journal of biological chemistry
Schmitt JM,Wayman GA,Nozaki N,Soderling TR
MA1-047 was used in western blot to study the mechanism of depolarization-induced ERK activation and neurite outgrowth.
Fri Jun 04 00:00:00 EDT 2004
Chronic psychosocial stress decreases calcineurin in the dentate gyrus: a possible mechanism for preservation of early ltp.
Neuroscience
Gerges NZ,Aleisa AM,Schwarz LA,Alkadhi KA
MA1-047 was used in western blot to study the role of decreased calcineurin expression in the dentate gyrus of chronically stressed rats in the protection of early LTP
Tue Jun 10 00:00:00 EDT 2003
Inhibitory autophosphorylation of CaMKII controls PSD association, plasticity, and learning.
Neuron
Elgersma Y,Fedorov NB,Ikonen S,Choi ES,Elgersma M,Carvalho OM,Giese KP,Silva AJ
MA1-047 was used in western blot to study the role of CaMKII inhibitory autophosphorylation in hippocampal plasticity and learning
Thu Oct 24 00:00:00 EDT 2002
Mitogen-activated protein kinase regulates early phosphorylation and delayed expression of Ca2+/calmodulin-dependent protein kinase II in long-term potentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Giovannini MG,Blitzer RD,Wong T,Asoma K,Tsokas P,Morrison JH,Iyengar R,Landau EM
MA1-047 was used in western blot to investigate the role of MAPK on the regulation of CaMKII expression
Sat Sep 15 00:00:00 EDT 2001
Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development.
Molecular and cellular biology
Esteban LM,Vicario-Abejón C,Fernández-Salguero P,Fernández-Medarde A,Swaminathan N,Yienger K,Lopez E,Malumbres M,McKay R,Ward JM,Pellicer A,Santos E
MA1-047 was used in immunocytochemistry to study the disparate roles of H-ras, N-ras, and K-ras during mouse development.
Thu Mar 01 00:00:00 EST 2001
Lamina-specific synaptic activation causes domain-specific alterations in dendritic immunostaining for MAP2 and CAM kinase II.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Steward O,Halpain S
MA1-047 was used in immunohistochemistry to show that the lamina-specific synaptic activation can produce domain-specific alterations in the molecular composition of dendrites
Wed Sep 15 00:00:00 EDT 1999
Tetanic stimulation leads to increased accumulation of Ca(2+)/calmodulin-dependent protein kinase II via dendritic protein synthesis in hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ouyang Y,Rosenstein A,Kreiman G,Schuman EM,Kennedy MB
MA1-047 was used in immunohistochemistry to show that the tetanic stimulation can cause an increase in the concentration of alpha-CaMKII in the dendrites of postsynaptic neurons
Wed Sep 15 00:00:00 EDT 1999
Adenylyl cyclase activation modulates activity-dependent changes in synaptic strength and Ca2+/calmodulin-dependent kinase II autophosphorylation.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Makhinson M,Chotiner JK,Watson JB,O'Dell TJ
MA1-047 was used in western blot to study the effects of adenylyl cyclase activators on activity-dependent changes in synaptic strength and on levels of autophosphorylated alphaCaMKII
Thu Apr 01 00:00:00 EST 1999
Gating of CaMKII by cAMP-regulated protein phosphatase activity during LTP.
Science (New York, N.Y.)
Blitzer RD,Connor JH,Brown GP,Wong T,Shenolikar S,Iyengar R,Landau EM
MA1-047 was used in western blot to study the effect of cAMP-regulated protein phosphatase activity on CaMKII function during long-term potentiation
Fri Jun 19 00:00:00 EDT 1998
Visualization of the distribution of autophosphorylated calcium/calmodulin-dependent protein kinase II after tetanic stimulation in the CA1 area of the hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ouyang Y,Kantor D,Harris KM,Schuman EM,Kennedy MB
MA1-047 was used in immunohistochemistry to investigate the autophosphorylation of CaMKII in the hippocampus after tetanic stimulation
Tue Jul 15 00:00:00 EDT 1997
Visualization of autophosphorylation of Ca2+/calmodulin-dependent protein kinase II in hippocampal slices.
Journal of neuroscience methods
Kindler S,Kennedy MB
MA1-047 was used in immunohistochemistry to investigate the localization of autophosphorylated calcium/calmodulin-dependent protein kinases II in hippocampal slices
Sun Sep 01 00:00:00 EDT 1996
