Product References
WITHDRAWN: Expression of Tmem41b and MMP13 associated with poor outcome in osteosarcomas.
Neoplasma
Li GH,Liu X,Feng LJ,Zhang L
Sun Aug 20 00:00:00 EDT 2023
Supramolecular nanofibers co-loaded with dabrafenib and doxorubicin for targeted and synergistic therapy of differentiated thyroid carcinoma.
Theranostics
Chen P,Cai X,Mu G,Duan Y,Jing C,Yang Z,Yang C,Wang X
Wed May 10 00:00:00 EDT 2023
Supramolecular nanofibers co-loaded with dabrafenib and doxorubicin for targeted and synergistic therapy of differentiated thyroid carcinoma.
Theranostics
Chen P,Cai X,Mu G,Duan Y,Jing C,Yang Z,Yang C,Wang X
Wed May 10 00:00:00 EDT 2023
NONO regulates B-cell development and B-cell receptor signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhang Y,Cui D,Huang M,Zheng Y,Zheng B,Chen L,Chen Q
Sat Apr 01 00:00:00 EDT 2023
Promotion of the genipin crosslinked chitosan-fiber hydrogel loaded with sustained release of clemastine fumarate in diabetic wound repair.
International journal of biological macromolecules
Zuo R,Shi J,Jiang S,Chu M,Wang Q,Kong L,Kang Q,Guo Y,Guan J
Tue Jan 31 00:00:00 EST 2023
Silica nanoparticles induce pulmonary damage in rats via VEGFC/D-VEGFR3 signaling-mediated lymphangiogenesis and remodeling.
Toxicology
Yu Y,Pan Y,Chang B,Zhao X,Qu K,Song Y
Sat Jul 01 00:00:00 EDT 2023
Prepubertal exposure to copper oxide nanoparticles induces Leydig cell injury with steroidogenesis disorders in mouse testes.
Biochemical and biophysical research communications
Zheng X,Chen J,Kang L,Wei Y,Wu Y,Hong Y,Wang X,Li D,Shen L,Long C,Wei G,Wu S
Sun Apr 30 00:00:00 EDT 2023
Elevated PGT promotes proliferation and inhibits cell apoptosis in preeclampsia by Erk signaling pathway.
Molecular and cellular probes
Pang H,Lei D,Huang J,Guo Y,Fan C
Wed Feb 01 00:00:00 EST 2023
ZNF133 is a potent suppressor in breast carcinogenesis through dampening L1CAM, a driver for tumor progression.
Oncogene
Li L,Wang X,Hu K,Liu X,Qiu L,Bai C,Cui Y,Wang B,Wang Z,Wang H,Cheng R,Hua J,Hai L,Wang M,Liu M,Song Z,Xiao C,Li B
Thu Jun 01 00:00:00 EDT 2023
Enhanced De Novo Lipid Synthesis Mediated by FASN Induces Chemoresistance in Colorectal Cancer.
Cancers
Han L,Dai W,Luo W,Ye L,Fang H,Mo S,Li Q,Xu Y,Wang R,Cai G
Tue Jan 17 00:00:00 EST 2023
Biochemical and clinical effects of RPS20 expression in renal clear cell carcinoma.
Oncology reports
Shen C,Chen Z,Zhang Y,Xu W,Peng R,Jiang J,Zuo W,Fan Y,Zheng B
Sun Jan 01 00:00:00 EST 2023
Endothelin-1 production via placental (pro)renin receptor in a mouse model of preeclampsia.
Placenta
Mishima S,Mitsui T,Tani K,Ooba H,Mitoma T,Ohira A,Maki J,Kirino S,Eto E,Hayata K,Masuyama H
Sat Jul 01 00:00:00 EDT 2023
PLX8394, a RAF inhibitor, inhibits enterovirus 71 replication by blocking RAF/MEK/ERK signaling.
Virologica Sinica
Wu C,Zhu G,Qiu F,Ren F,Lin B,Zhang D,Yang Q,Huang C
Sat Apr 01 00:00:00 EDT 2023
Norepinephrine/β2-Adrenergic Receptor Pathway Promotes the Cell Proliferation and Nerve Growth Factor Production in Triple-Negative Breast Cancer.
Journal of breast cancer
Jin M,Wang Y,Zhou T,Li W,Wen Q
Thu Jun 01 00:00:00 EDT 2023
MLK3 silence suppressed osteogenic differentiation and delayed bone formation via influencing the bone metabolism and disturbing MAPK signaling.
Journal of orthopaedic translation
Yang X,Mai YX,Wei L,Peng LY,Pang FX,Wang LJ,Li ZP,Zhang JF,Jin AM
Sun Jan 01 00:00:00 EST 2023
Neuroprotective effect of histamine H3 receptor blockade on methamphetamine-induced cognitive impairment in mice.
Pharmacology, biochemistry, and behavior
Luo H,Li X,Fan R,Ruan Y,Qian L,Shen Y,Si Z,Li L,Liu Y
Sun Jan 01 00:00:00 EST 2023
Luteoloside Induces G0/G1 Phase Arrest of Neuroblastoma Cells by Targeting p38 MAPK.
Molecules (Basel, Switzerland)
He Y,Luo M,Lei S,Zeng Z,Chen T,Wu Y,Wang D,Wang L,Wang L
Sun Feb 12 00:00:00 EST 2023
Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.
The American journal of pathology
Chen X,Song QL,Wang JY,Ji R,Li ZH,Cao ML,Mu XF,Guo DY,Zhang Y,Yang J
Tue Aug 01 00:00:00 EDT 2023
BIBF1120 Protects against Diabetic Retinopathy through Neovascularization-Related Molecules and the MAPK Signaling Pathway.
Journal of ophthalmology
Cao X,Li T,Tian Y,Tian Y,Gao C,Zhang D,Song Y
Tue May 09 00:00:00 EDT 2023
Anti-inflammatory effect of Irisin on LPS-stimulated macrophages through inhibition of MAPK pathway.
Physiological research
Ma Y,Du Y,Yang J,He Q,Wang H,Lin X
Sun Apr 30 00:00:00 EDT 2023
TRIM11 Posttranscriptionally Modulated by miR-5193 Facilitates Tumor Growth and Metastasis of Prostate Cancer.
Technology in cancer research & treatment
Pan Y,Yu H,Lu F
Wed May 31 00:00:00 EDT 2023
Corilagin ameliorates macrophages inflammation in atherosclerosis through TLR4-NFκB/MAPK pathway.
Heliyon
Meng D,Deng X,Wu Y,Wu J,Zhang Y,Zhang J,Zhao Y,Che Y
Thu Jun 01 00:00:00 EDT 2023
Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation.
World journal of surgical oncology
Cheng X,Jia X,Wang C,Zhou S,Chen J,Chen L,Chen J
Tue Mar 28 00:00:00 EDT 2023
Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog pathway inhibitor-1.
Nature communications
Bagka M,Choi H,Héritier M,Schwaemmle H,Pasquer QTL,Braun SMG,Scapozza L,Wu Y,Hoogendoorn S
Sat Jul 01 00:00:00 EDT 2023
Subchronic Microcystin-LR Aggravates Colorectal Inflammatory Response and Barrier Disruption via Raf/ERK Signaling Pathway in Obese Mice.
Toxins
Yang Y,Zheng S,Chu H,Du C,Chen M,Emran MY,Chen J,Yang F,Tian L
Sat Apr 01 00:00:00 EDT 2023
Nucleophilic covalent ligand discovery for the cysteine redoxome.
Nature chemical biology
Fu L,Jung Y,Tian C,Ferreira RB,Cheng R,He F,Yang J,Carroll KS
Wed Nov 01 00:00:00 EDT 2023
PM2.5 exposure exacerbates mice thoracic aortic aneurysm and dissection by inducing smooth muscle cell apoptosis via the MAPK pathway.
Chemosphere
Ming Y,Zhou X,Liu G,Abudupataer M,Zhu S,Xiang B,Yin X,Lai H,Sun Y,Wang C,Li J,Zhu K
Wed Feb 01 00:00:00 EST 2023
Transcription factor ETS proto-oncogene 1 contributes to neuropathic pain by regulating histone deacetylase 1 in primary afferent neurons.
Molecular pain
Zheng HL,Sun SY,Jin T,Zhang M,Zeng Y,Liu Q,Yang K,Wei R,Pan Z,Lin F
Sun Feb 12 00:00:00 EST 2023
Roxadustat alleviates nitroglycerin-induced migraine in mice by regulating HIF-1α/NF-κB/inflammation pathway.
Acta pharmacologica Sinica
Yang DG,Gao YY,Yin ZQ,Wang XR,Meng XS,Zou TF,Duan YJ,Chen YL,Liao CZ,Xie ZL,Fan XD,Sun L,Han JH,Yang XX
Wed Feb 01 00:00:00 EST 2023
Naringenin Attenuates Isoprenaline-Induced Cardiac Hypertrophy by Suppressing Oxidative Stress through the AMPK/NOX2/MAPK Signaling Pathway.
Nutrients
Li Y,He B,Zhang C,He Y,Xia T,Zeng C
Thu Mar 09 00:00:00 EST 2023
Geraniol prevents Helicobacterium pylori-induced human gastric cancer signalling by enhancing peroxiredoxin-1 expression in GES-1 cells.
Microbial pathogenesis
Zhuang K,Tang H,Guo H,Yuan S
Sun Jan 01 00:00:00 EST 2023
Macrophage-Derived Cathepsin S Remodels the Extracellular Matrix to Promote Liver Fibrogenesis.
Gastroenterology
Zuo T,Xie Q,Liu J,Yang J,Shi J,Kong D,Wang Y,Zhang Z,Gao H,Zeng DB,Wang X,Tao P,Wei W,Wang J,Li Y,Long Q,Li C,Chang L,Ning H,Li Y,Cui C,Ge X,Wu J,Li G,Hong X,Yang X,Dai E,He F,Wu J,Ruan Y,Lu S,Xu P
Fri Sep 01 00:00:00 EDT 2023
Flotillin-1 is a prognostic biomarker for glioblastoma and promotes cancer development through enhancing invasion and altering tumour microenvironment.
Journal of cellular and molecular medicine
Wang R,Chen Z,Zhang Y,Xiao S,Zhang W,Hu X,Xiao Q,Liu Q,Wang X
Wed Feb 01 00:00:00 EST 2023
Parecoxib attenuates inflammation injury in septic H9c2 cells by regulating the MAPK signaling pathway.
Experimental and therapeutic medicine
Qian X,Xiong S,Chen Q,Zhang J,Xie J
Sat Apr 01 00:00:00 EDT 2023
Carnosic Acid Attenuates AβOs-Induced Apoptosis and Synaptic Impairment via Regulating NMDAR2B and Its Downstream Cascades in SH-SY5Y Cells.
Molecular neurobiology
Liu WY,Li Y,Li Y,Xu LZ,Jia JP
Sun Jan 01 00:00:00 EST 2023
Exercise-induced endothelial Mecp2 lactylation suppresses atherosclerosis via the Ereg/MAPK signalling pathway.
Atherosclerosis
Wang Y,Chen L,Zhang M,Li X,Yang X,Huang T,Ban Y,Li Y,Li Q,Zheng Y,Sun Y,Wu J,Yu B
Thu Jun 01 00:00:00 EDT 2023
Exercise-induced endothelial Mecp2 lactylation suppresses atherosclerosis via the Ereg/MAPK signalling pathway.
Atherosclerosis
Wang Y,Chen L,Zhang M,Li X,Yang X,Huang T,Ban Y,Li Y,Li Q,Zheng Y,Sun Y,Wu J,Yu B
Thu Jun 01 00:00:00 EDT 2023
Exercise-induced endothelial Mecp2 lactylation suppresses atherosclerosis via the Ereg/MAPK signalling pathway.
Atherosclerosis
Wang Y,Chen L,Zhang M,Li X,Yang X,Huang T,Ban Y,Li Y,Li Q,Zheng Y,Sun Y,Wu J,Yu B
Thu Jun 01 00:00:00 EDT 2023
CRIP1 supports the growth and migration of AML-M5 subtype cells by activating Wnt/β-catenin pathway.
Leukemia research
Deng X,Zeng Y,Qiu X,Zhong M,Xiong X,Luo M,Zhang J,Chen X
Sat Jul 01 00:00:00 EDT 2023
Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity.
Journal of medicinal chemistry
Liu XM,Li Z,Xie XR,Wang JQ,Qiao X,Qiao X,Xie CZ,Xu JY
Thu Feb 09 00:00:00 EST 2023
Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity.
Journal of medicinal chemistry
Liu XM,Li Z,Xie XR,Wang JQ,Qiao X,Qiao X,Xie CZ,Xu JY
Thu Feb 09 00:00:00 EST 2023
FSH promotes immature porcine Sertoli cell proliferation by activating the CCR7/Ras-ERK signaling axis.
Reproduction (Cambridge, England)
Yin Y,Ma J,Lu X,Yan S,Jiang Q,Wu D,Chen B,Weng B,Ran M
Thu Jun 01 00:00:00 EDT 2023
CHAC2 promotes lung adenocarcinoma by regulating ROS-mediated MAPK pathway activation.
Journal of Cancer
Peng W,Wen L,Jiang R,Deng J,Chen M
Thu Jun 08 00:00:00 EDT 2023
CHAC2 promotes lung adenocarcinoma by regulating ROS-mediated MAPK pathway activation.
Journal of Cancer
Peng W,Wen L,Jiang R,Deng J,Chen M
Thu Jun 08 00:00:00 EDT 2023
CHAC2 promotes lung adenocarcinoma by regulating ROS-mediated MAPK pathway activation.
Journal of Cancer
Peng W,Wen L,Jiang R,Deng J,Chen M
Thu Jun 08 00:00:00 EDT 2023
CHAC2 promotes lung adenocarcinoma by regulating ROS-mediated MAPK pathway activation.
Journal of Cancer
Peng W,Wen L,Jiang R,Deng J,Chen M
Thu Jun 08 00:00:00 EDT 2023
An unconventional cancer-promoting function of methamphetamine in hepatocellular carcinoma.
Life science alliance
Si Z,Yang G,Wang X,Yu Z,Pang Q,Zhang S,Qian L,Ruan Y,Huang J,Yu L
Wed Mar 01 00:00:00 EST 2023
The E3 ligase RBCK1 reduces the sensitivity of ccRCC to sunitinib through the ANKRD35-MITD1-ANXA1 axis.
Oncogene
Wang Y,Peng M,Zhong Y,Xiong W,Zhu L,Jin X
Wed Mar 01 00:00:00 EST 2023
Upregulated desmin/integrin β1/MAPK axis promotes elastic cartilage regeneration with increased ECM mechanical strength.
International journal of biological sciences
Zhang W,Lu W,Yu Q,Liu X,Jiang H
Mon Jun 19 00:00:00 EDT 2023
Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis.
Immunology
Gou Y,Wang H,Wang T,Wang H,Wang B,Jiao N,Yu Y,Cao Y,Wang H,Zhang Z
Wed Mar 01 00:00:00 EST 2023
Kaempferol promotes melanogenesis and reduces oxidative stress in PIG1 normal human skin melanocytes.
Journal of cellular and molecular medicine
Xie Y,Mei X,Shi W
Sat Apr 01 00:00:00 EDT 2023
Caveolae-associated protein 3 promotes adipogenic differentiation of porcine preadipocytes by promoting extracellular signal-regulated kinase phosphorylation.
Animal science journal = Nihon chikusan Gakkaiho
Shi M,Yang S,Huang X,Wang S,Li W,Yun J,Lu C,Yang Y,Cai C,Gao P,Guo X,Li B,Cao G
Mon Mar 20 00:00:00 EDT 2023
TOMM34 promotes cell proliferation, migration, and invasion of OSCC and modulates mitochondrial function.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Huang Y,Chen Z,Chen X,Chen X,Xu M
Sun Jan 01 00:00:00 EST 2023
ROS-activated MAPK/ERK pathway regulates crosstalk between Nrf2 and Hif-1α to promote IL-17D expression protecting the intestinal epithelial barrier under hyperoxia.
International immunopharmacology
Wang P,Li T,Niu C,Sun S,Liu D
Wed Mar 01 00:00:00 EST 2023
ROS-activated MAPK/ERK pathway regulates crosstalk between Nrf2 and Hif-1α to promote IL-17D expression protecting the intestinal epithelial barrier under hyperoxia.
International immunopharmacology
Wang P,Li T,Niu C,Sun S,Liu D
Wed Mar 01 00:00:00 EST 2023
Serum Exosomes From Epithelial Ovarian Cancer Patients Contain LRP1, Which Promotes the Migration of Epithelial Ovarian Cancer Cell.
Molecular & cellular proteomics : MCP
Zhou W,Ma J,Zhao H,Wang Q,Guo X,Chen L,Cao Z,Xu J,Zhang B,Zhou X
Sat Apr 01 00:00:00 EDT 2023
Holothuria leucospilota Polysaccharides Improve Immunity and the Gut Microbiota in Cyclophosphamide-Treated Immunosuppressed Mice.
Molecular nutrition & food research
Zhao F,Ma T,Zhang X,Zhao Q,Zhu K,Cao J,Liu Z,Shen X,Li C
Sat Apr 01 00:00:00 EDT 2023
SLC27A2 mediates FAO in colorectal cancer through nongenic crosstalk regulation of the PPARs pathway.
BMC cancer
Shang K,Ma N,Che J,Li H,Hu J,Sun H,Cao B
Tue Apr 11 00:00:00 EDT 2023
SARS-CoV-2 E protein-induced THP-1 pyroptosis is reversed by Ruscogenin.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Huang H,Li X,Zha D,Lin H,Yang L,Wang Y,Xu L,Wang L,Lei T,Zhou Z,Xiao YF,Xin HB,Fu M,Qian Y
Tue Aug 01 00:00:00 EDT 2023
Prognosis-related VDAC1 regulates the proliferation and apoptosis of osteosarcoma cells via the MAPK signaling pathway.
Genomics
Cai X,Zhu S
Mon May 01 00:00:00 EDT 2023
Effective-compound combination of Bufei Yishen formula III combined with ER suppress airway mucus hypersecretion in COPD rats: via EGFR/MAPK signaling.
Bioscience reports
Xu K,Ma J,Lu R,Shao X,Zhao Y,Cui L,Qiu Z,Tian Y,Li J
Thu Nov 30 00:00:00 EST 2023
Angiotensin-(1-7) ameliorates sepsis-induced cardiomyopathy by alleviating inflammatory response and mitochondrial damage through the NF-κB and MAPK pathways.
Journal of translational medicine
Chen XS,Cui JR,Meng XL,Wang SH,Wei W,Gao YL,Shou ST,Liu YC,Chai YF
Mon Jan 02 00:00:00 EST 2023
Six first-line tyrosine kinase inhibitors reveal novel inhibition potential for the EGFR S768I mutation.
Toxicology and applied pharmacology
Wang Y,Liu Q,Chu C,Li L,Wang Z,Liu Q,Wu G,Wei X,An L,Ma J
Wed Feb 15 00:00:00 EST 2023
Blocking circadian clock factor Rev-erbα inhibits growth plate chondrogenesis via up-regulating MAPK-ERK1/2 pathway.
Cell cycle (Georgetown, Tex.)
Qian Z,Liu Z,Feng Z,Cai Z,Qiu Y,Zhu Z
Sun Jan 01 00:00:00 EST 2023
Exosomes incorporated with black phosphorus quantum dots attenuate retinal angiogenesis via disrupting glucose metabolism.
Materials today. Bio
Gui X,Zhang H,Zhang R,Li Q,Zhu W,Nie Z,Zhao J,Cui X,Hao W,Wen X,Shen W,Song H
Sat Apr 01 00:00:00 EDT 2023
Tumor Necrosis Factor-α Promotes the Tumorigenesis, Lymphangiogenesis, and Lymphatic Metastasis in Cervical Cancer via Activating VEGFC-Mediated AKT and ERK Pathways.
Mediators of inflammation
Chen X,Lin L,Wu Q,Li S,Wang H,Sun Y
Sat Oct 28 00:00:00 EDT 2023
Annexin A2 promotes angiogenesis after ischemic stroke via annexin A2 receptor - AKT/ERK pathways.
Neuroscience letters
Lin H,Li W,Shen Z,Bei Y,Wei T,Yu Z,Dai Y,Dai H
Sun Jan 01 00:00:00 EST 2023
Tong Sai granule improves AECOPD via regulation of MAPK-SIRT1-NF-κB pathway and cellular senescence alleviation.
Journal of ethnopharmacology
Tao L,Lu X,Fu Z,Tian Y,Liu X,Li J,Zhao P
Thu Oct 05 00:00:00 EDT 2023
Targeting ARF1-IQGAP1 interaction to suppress colorectal cancer metastasis and vemurafenib resistance.
Journal of advanced research
Hu HF,Gao GB,He X,Li YY,Li YJ,Li B,Pan Y,Wang Y,He QY
Fri Sep 01 00:00:00 EDT 2023
TAF15 promotes cell proliferation, migration and invasion of gastric cancer via activation of the RAF1/MEK/ERK signalling pathway.
Scientific reports
Tang L,Guo C,Li X,Zhang B,Huang L
Mon Apr 10 00:00:00 EDT 2023
Liver X receptor agonists exert antitumor effects against hepatocellular carcinoma via inducing REPS2 expression.
Acta pharmacologica Sinica
He XY,Zhu MM,Zheng J,Wang CY,Zhao XK,Zhang BT,Zhou DC,Zhang S,Yang XX,Duan YJ,Han JH,Chen YL
Wed Mar 01 00:00:00 EST 2023
Dysfunctional microRNA-144-3p/ZBTB20/ERK/CREB1 signalling pathway is associated with MK-801-induced schizophrenia-like abnormalities.
Brain research
Pan B,Han B,Zhu X,Wang Y,Ji H,Weng J,Liu Y
Sun Jan 01 00:00:00 EST 2023
Low Pi stress enhances the sensitivity of hepatocellular carcinoma to sorafenib.
Biochemical pharmacology
Bi QC,Deng ZQ,Lv YF,Liu Y,Xie CS,He YQ,Tang Q
Sat Jul 01 00:00:00 EDT 2023
Methionine sulfoxide suppresses adipogenic differentiation by regulating the mitogen-activated protein kinase signaling pathway.
Cell biology international
Qin D,Lei Y,Xie W,Zheng Q,Peng Z,Liu Y,Dai B,Ma T,Wei P,Gao C,Guo X,Gao J,Zhao J,Du J,Zeng Q,Zhang Z,Dong X,Shen H
Wed Mar 01 00:00:00 EST 2023
Peptide-anchored neutrophil membrane-coated biomimetic nanodrug for targeted treatment of rheumatoid arthritis.
Journal of nanobiotechnology
Yang N,Li M,Wu L,Song Y,Yu S,Wan Y,Cheng W,Yang B,Mou X,Yu H,Zheng J,Li X,Yu X
Fri Jan 13 00:00:00 EST 2023
Sema3A inactivates the ERK/JNK signalling pathways to alleviate inflammation and oxidative stress in lipopolysaccharide-stimulated rat endothelial cells and lung tissues.
Autoimmunity
Qiu Q,Yu X,Chen Q,He X
Fri Dec 01 00:00:00 EST 2023
Verniciflavanol A, a profisetinidin-type-4-arylflavan-3-ol from toxicodendron vernicifluum protects SH-SY5Y cells against H2O2-Induced oxidative stress.
Phytochemistry
Li M,Zhang Y,Han T,Guan L,Fan D,Wu Q,Liu J,Xu Y,Fan Y
Sun Jan 01 00:00:00 EST 2023
Persistent Degradation of HER2 Protein by Hybrid nanoPROTAC for Programmed Cell Death.
Journal of medicinal chemistry
Wang Z,Tan M,Su W,Huang W,Zhang J,Jia F,Cao G,Liu X,Song H,Ran H,Nie G,Wang H
Thu May 11 00:00:00 EDT 2023
Alkaloids from Piper longum Exhibit Anti-inflammatory Activity and Synergistic Effects with Chemotherapeutic Agents against Cervical Cancer Cells.
Journal of agricultural and food chemistry
Wan Q,Xu J,Zhu C,Liu X,Tu Y,Lei J,Yu J
Wed Jul 12 00:00:00 EDT 2023
HIV Tat-Conjugated Histone H3 Peptides Induce Tumor Cell Death Via Cellular Stress Responses.
Human gene therapy
Xu Q,Zhu F,Pan Y,Ren Y,Li J,Huang N,Liu K,Wang Y
Sun Jan 01 00:00:00 EST 2023
BST2 regulated by the transcription factor STAT1 can promote metastasis, invasion and proliferation of oral squamous cell carcinoma via the AKT/ERK1/2 signaling pathway.
International journal of oncology
Shan F,Shen S,Wang X,Chen G
Sat Apr 01 00:00:00 EDT 2023
Jia-Wei-Si-Miao-Yong-An Fang stimulates the healing of acute radiation-induced cutaneous wounds through MAPK/ERK pathway.
Journal of ethnopharmacology
Wang Y,Gao J,Sun L,Li Q,Kang N,Gao C,Li T
Mon Apr 24 00:00:00 EDT 2023
Neuropeptide Y Promotes the Treatment of Adipose Stem Cells on Type 2 Diabetic Wounds.
Tissue engineering and regenerative medicine
Lu T,Cong L,Jiang T,Dong X,Song L
Tue Aug 01 00:00:00 EDT 2023
Engineered Microparticles for Treatment of Murine Brain Metastasis by Reprograming Tumor Microenvironment and Inhibiting MAPK Pathway.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Lu L,Zi H,Zhou J,Huang J,Deng Z,Tang Z,Li L,Shi X,Lo PC,Lovell JF,Deng D,Wan C,Jin H
Wed Mar 01 00:00:00 EST 2023
CircRNA_0017076 acts as a sponge for miR-185-5p in the control of epithelial-to-mesenchymal transition of tubular epithelial cells during renal interstitial fibrosis.
Human cell
Zhang F,Zou H,Li X,Liu J,Xie Y,Chen M,Yu J,Wu X,Guo B
Mon May 01 00:00:00 EDT 2023
Endothelial progenitor cell-derived exosomes inhibit pulmonary artery smooth muscle cell in vitro proliferation and resistance to apoptosis by modulating the Mitofusin-2 and Ras-Raf-ERK1/2 signaling pathway.
European journal of pharmacology
Liu P,Gao S,Li Z,Pan S,Luo G,Ji Z
Thu Jun 15 00:00:00 EDT 2023
Metabotropic glutamate receptor 5 upregulation of γ-aminobutyric acid transporter 3 expression ameliorates cognitive impairment after traumatic brain injury in mice.
Brain research bulletin
Xu P,Huang X,Niu W,Yu D,Zhou M,Wang H
Wed Jun 01 00:00:00 EDT 2022
Network Pharmacology and Experimental Verification to Explore the Potential Mechanism of Yin-Huo-Tang for Lung Adenocarcinoma Recurrence.
Drug design, development and therapy
Liu D,Lin S,Li Y,Zhou T,Hu K,Li Q
Mon Apr 04 00:00:00 EDT 2022
Astrocytes Derived from Familial and Sporadic Alzheimer's Disease iPSCs Show Altered Calcium Signaling and Respond Differently to Misfolded Protein Tau.
Cells
Brezovakova V,Sykova E,Jadhav S
Fri Apr 22 00:00:00 EDT 2022
Effects of Poria cocos extract on metabolic dysfunction-associated fatty liver disease via the FXR/PPARα-SREBPs pathway.
Frontiers in pharmacology
He J,Yang Y,Zhang F,Li Y,Li X,Pu X,He X,Zhang M,Yang X,Yu Q,Qi Y,Li X,Yu J
Mon Jun 05 00:00:00 EDT 2023
Synthesis and biological evaluation of 4-(4-aminophenyl)-6-methylisoxazolo[3,4-b] pyridin-3-amine covalent inhibitors as potential agents for the treatment of acute myeloid leukemia.
Bioorganic & medicinal chemistry
Kang JB,Chen L,Leng XJ,Wang JJ,Cheng Y,Wu SH,Ma YY,Yang LJ,Cao YH,Yang X,Tong ZJ,Wu JZ,Wang YB,Zhou H,Liu JC,Ding N,Dai WC,Yu YC,Xue X,Sun SL,Dai XB,Chang L,Wang XL,Li NG,Shi ZH
Thu Sep 15 00:00:00 EDT 2022
Hexachlorophene, a selective SHP2 inhibitor, suppresses proliferation and metastasis of KRAS-mutant NSCLC cells by inhibiting RAS/MEK/ERK and PI3K/AKT signaling pathways.
Toxicology and applied pharmacology
Fu NJ,Xi RY,Shi XK,Li RZ,Zhang ZH,Li LY,Zhang GL,Wang F
Fri Apr 15 00:00:00 EDT 2022
Combination of RSK inhibitor LJH-685 and FLT3 inhibitor FF-10101 promoted apoptosis and proliferation inhibition of AML cell lines.
Cellular oncology (Dordrecht)
Zhang S,Liu J,Lu ZY,Xue YT,Mu XR,Liu Y,Cao J,Li ZY,Li F,Xu KL,Wu QY
Sat Oct 01 00:00:00 EDT 2022
Smart thermosensitive poloxamer hydrogels loaded with Nr-CWs for the treatment of diabetic wounds.
PloS one
Wang J,Zhao B,Sun L,Jiang L,Li Q,Jin P
Tue Jan 03 00:00:00 EST 2023
KGF-2 Regulates STAP-2-Mediated Signal Transducer and Activator of Transcription 3 Signaling and Reduces Skin Scar Formation.
The Journal of investigative dermatology
Zhou Q,Gong J,Bi J,Yang X,Zhang L,Lu C,Li L,Chen M,Cai J,Yang R,Li X,Li Z,Wang X
Fri Jul 01 00:00:00 EDT 2022
Homer1 promotes the conversion of A1 astrocytes to A2 astrocytes and improves the recovery of transgenic mice after intracerebral hemorrhage.
Journal of neuroinflammation
Fei X,Dou YN,Wang L,Wu X,Huan Y,Wu S,He X,Lv W,Wei J,Fei Z
Mon Mar 14 00:00:00 EDT 2022
Cpd-0225 attenuates renal fibrosis via inhibiting ALK5.
Biochemical pharmacology
Xie SS,Dong ZH,He Y,Chen ZW,Yang Q,Ma WX,Li C,Chen Y,Wang JN,Yu JT,Xu CH,Ni WJ,Hou R,Suo XG,Wen JG,Jin J,Li J,Liu MM,Meng XM
Sat Oct 01 00:00:00 EDT 2022
Dibutyltin dichloride exposure affects mouse oocyte quality by inducing spindle defects and mitochondria dysfunction.
Chemosphere
Lu Y,Tang H,Wang X,Xu J,Sun F
Sun May 01 00:00:00 EDT 2022
GALNT8 suppresses breast cancer cell metastasis potential by regulating EGFR O-GalNAcylation.
Biochemical and biophysical research communications
Huang T,Meng F,Huang H,Wang L,Wang L,Liu Y,Liu Y,Wang J,Li W,Zhang J,Liu Y
Sat Apr 23 00:00:00 EDT 2022
Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.
Molecular pharmaceutics
Yang X,Shang P,Ji J,Malichewe C,Yao Z,Liao J,Du D,Sun C,Wang L,Tang YJ,Guo X
Mon Jan 03 00:00:00 EST 2022
Ribosomal protein RPL5 regulates colon cancer cell proliferation and migration through MAPK/ERK signaling pathway.
BMC molecular and cell biology
Zhang H,Liu J,Dang Q,Wang X,Chen J,Lin X,Yang N,Du J,Shi H,Liu Y,Han J
Wed Nov 16 00:00:00 EST 2022
EDARADD silencing suppresses the proliferation and migration of bladder cancer cells.
Urologic oncology
Fang Z,Yang X,Wei X,Yang Y,Yi C,Song D
Mon Aug 01 00:00:00 EDT 2022
Oleuropein ameliorated lung ischemia-reperfusion injury by inhibiting TLR4 signaling cascade in alveolar macrophages.
Transplant immunology
Xu Z,Sun X,Ding B,Zi M,Ma Y
Sat Oct 01 00:00:00 EDT 2022
A Regulatory Loop Involving miR-200c and NF-κB Modulates Mortalin Expression and Increases Cisplatin Sensitivity in an Ovarian Cancer Cell Line Model.
International journal of molecular sciences
Huang X,Yan Y,Gui A,Zhu S,Qiu S,Chen F,Liu W,Zuo J,Yang L
Sun Dec 04 00:00:00 EST 2022
Berberine protects against chronic cerebral hypoperfusion-induced cognitive impairment and hippocampal damage via regulation of the ERK/Nrf2 pathway.
Journal of chemical neuroanatomy
Wang N,Tian Y,Yan F,Zhao F,Wang R,Luo Y,Zheng Y
Thu Sep 01 00:00:00 EDT 2022
PTPRO represses colorectal cancer tumorigenesis and progression by reprogramming fatty acid metabolism.
Cancer communications (London, England)
Dai W,Xiang W,Han L,Yuan Z,Wang R,Ma Y,Yang Y,Cai S,Xu Y,Mo S,Li Q,Cai G
Thu Sep 01 00:00:00 EDT 2022
Dihydromyricetin Enhances Intestinal Antioxidant Capacity of Growing-Finishing Pigs by Activating ERK/Nrf2/HO-1 Signaling Pathway.
Antioxidants (Basel, Switzerland)
Wei C,Chen X,Chen D,Yu B,Zheng P,He J,Chen H,Yan H,Luo Y,Huang Z
Sat Apr 02 00:00:00 EDT 2022
Sufentanil Alleviates Sepsis-Induced Myocardial Injury and Stress Response in Rats through the ERK/GSK-3β Signaling Axis.
Evidence-based complementary and alternative medicine : eCAM
Zang H,Shao G,Lou Y
Fri Aug 11 00:00:00 EDT 2023
Rhodococcus equi-Derived Extracellular Vesicles Promoting Inflammatory Response in Macrophage through TLR2-NF-κB/MAPK Pathways.
International journal of molecular sciences
Xu Z,Hao X,Li M,Luo H
Sun Aug 28 00:00:00 EDT 2022
Progesterone activates GPR126 to promote breast cancer development via the Gi pathway.
Proceedings of the National Academy of Sciences of the United States of America
An W,Lin H,Ma L,Zhang C,Zheng Y,Cheng Q,Ma C,Wu X,Zhang Z,Zhong Y,Wang M,He D,Yang Z,Du L,Feng S,Wang C,Yang F,Xiao P,Zhang P,Yu X,Sun JP
Tue Apr 12 00:00:00 EDT 2022
Plasma-Based Metabolomics Profiling of High-Risk Human Papillomavirus and their Emerging Roles in the Progression of Cervical Cancer.
BioMed research international
Chen A,Xu M,Chen J,Chen T,Wang Q,Zhang R,Qiu J
Mon Nov 21 00:00:00 EST 2022
Salidroside inhibited cerebral ischemia/reperfusion-induced oxidative stress and apoptosis via Nrf2/Trx1 signaling pathway.
Metabolic brain disease
Li F,Mao Q,Wang J,Zhang X,Lv X,Wu B,Yan T,Jia Y
Thu Dec 01 00:00:00 EST 2022
Biotransformation of 18β-Glycyrrhetinic Acid by Human Intestinal Fungus Aspergillus niger RG13B1 and the Potential Anti-Inflammatory Mechanism of Its Metabolites.
Journal of agricultural and food chemistry
Zhang M,Zhang J,Wang C,Yan JK,Yi J,Ning J,Huo XK,Yu ZL,Zhang BJ,Sun CP,Ma XC
Wed Dec 07 00:00:00 EST 2022
Downregulation of IL-8 and IL-10 by the Activation of Ca2+-Activated K+ Channel KCa3.1 in THP-1-Derived M2 Macrophages.
International journal of molecular sciences
Ohya S,Matsui M,Kajikuri J,Kito H,Endo K
Wed Aug 03 00:00:00 EDT 2022
Losartan attenuates sepsis-induced cardiomyopathy by regulating macrophage polarization via TLR4-mediated NF-κB and MAPK signaling.
Pharmacological research
Chen XS,Wang SH,Liu CY,Gao YL,Meng XL,Wei W,Shou ST,Liu YC,Chai YF
Tue Nov 01 00:00:00 EDT 2022
Effects of Camk2b Overexpression and Underexpression on the Proteome of Rat Hippocampal Neurons.
Neuroscience
Yang C,Zhang M,Li S,Yi F,Huang H,Xie H,Liu H,Huang R,Zhou J
Tue Nov 01 00:00:00 EDT 2022
Dysfunction of CCR1+ decidual macrophages is a potential risk factor in the occurrence of unexplained recurrent pregnancy loss.
Frontiers in immunology
Sang Y,Li Y,Xu L,Chen J,Li D,Du M
Tue Dec 20 00:00:00 EST 2022
Immune-enhancing effects of postbiotic produced by Bacillus velezensis Kh2-2 isolated from Korea Foods.
Food research international (Ottawa, Ont.)
Mi XJ,Tran THM,Park HR,Xu XY,Subramaniyam S,Choi HS,Kim J,Koh SC,Kim YJ
Tue Feb 01 00:00:00 EST 2022
Lignans from Mosla scabra Ameliorated Influenza A Virus-Induced Pneumonia via Inhibiting Macrophage Activation.
Evidence-based complementary and alternative medicine : eCAM
Cai W,Wu LR,Zhang SL
Wed Aug 10 00:00:00 EDT 2022
Hypoglycemia-Exacerbated Mitochondrial Connexin 43 Accumulation Aggravates Cardiac Dysfunction in Diabetic Cardiomyopathy.
Frontiers in cardiovascular medicine
Wei X,Chang ACH,Chang H,Xu S,Xue Y,Zhang Y,Lei M,Chang ACY,Zhang Q
Tue Apr 05 00:00:00 EDT 2022
Employing CRISPR-Cas9 to Generate CD133 Synthetic Lethal Melanoma Stem Cells.
International journal of molecular sciences
Simbulan-Rosenthal CM,Haribabu Y,Vakili S,Kuo LW,Clark H,Dougherty R,Alobaidi R,Carney B,Sykora P,Rosenthal DS
Sun Feb 20 00:00:00 EST 2022
The Immune-Enhancing Properties of Hwanglyeonhaedok-Tang-Mediated Biosynthesized Gold Nanoparticles in Macrophages and Splenocytes.
International journal of nanomedicine
Mi XJ,Xu XY,Choi HS,Kim H,Cho IH,Yi TH,Kim YJ
Tue Feb 08 00:00:00 EST 2022
Dihydrohomoplantagin and Homoplantaginin, Major Flavonoid Glycosides from Salvia plebeia R. Br. Inhibit oxLDL-Induced Endothelial Cell Injury and Restrict Atherosclerosis via Activating Nrf2 Anti-Oxidation Signal Pathway.
Molecules (Basel, Switzerland)
Meng N,Chen K,Wang Y,Hou J,Chu W,Xie S,Yang F,Sun C
Sat Mar 19 00:00:00 EDT 2022
Farrerol prevents Angiotensin II-induced cardiac remodeling in vivo and in vitro.
Frontiers in pharmacology
He J,Xu D,Wang L,Yu X
Thu Feb 02 00:00:00 EST 2023
HIV-1 Tat Protein-Mediated Inflammatory Response Inhibits the Erythroid Hematopoietic Support Function of Bone Marrow Mesenchymal Stem Cells.
AIDS research and human retroviruses
Wang X,Chen M,Ma S,Ding Y,Zhou C,Yuan Y
Thu Sep 01 00:00:00 EDT 2022
7-Methylxanthine Influences the Behavior of ADORA2A-DRD2 Heterodimers in Human Retinal Pigment Epithelial Cells.
Ophthalmic research
Fan Y,Li J,Huang L,Wang K,Zhao M
Thu Dec 15 00:00:00 EST 2022
Downregulation of estrogen receptor-α36 expression attenuates metastasis of hepatocellular carcinoma cells.
Environmental toxicology
Wang R,Chen J,Yu H,Wei Z,Ma M,Ye X,Wu W,Chen H,Fu Z
Sun May 01 00:00:00 EDT 2022
Sclareol ameliorates hyperglycemia-induced renal injury through inhibiting the MAPK/NF-κB signaling pathway.
Phytotherapy research : PTR
Han X,Zhang J,Zhou L,Wei J,Tu Y,Shi Q,Zhang Y,Ren J,Wang Y,Ying H,Liang G
Wed Jun 01 00:00:00 EDT 2022
PI3K inhibitor impairs tumor progression and enhances sensitivity to anlotinib in anlotinib-resistant osteosarcoma.
Cancer letters
Chen C,Guo Y,Huang Q,Wang B,Wang W,Niu J,Lou J,Xu J,Ren T,Huang Y,Guo W
Tue Jun 28 00:00:00 EDT 2022
Tetrahydrocurcumin improves lipopolysaccharide-induced myocardial dysfunction by inhibiting oxidative stress and inflammation via JNK/ERK signaling pathway regulation.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhu H,Zhang L,Jia H,Xu L,Cao Y,Zhai M,Li K,Xia L,Jiang L,Li X,Zhou Y,Liu J,Yu S,Duan W
Thu Sep 01 00:00:00 EDT 2022
Immunomodulatory activity of aqueous extract from Crassostrea sikamea in the splenocytes of Sprague-Dawley rats.
Food science & nutrition
Guo G,Kong Y,Su J,Wang G,Zhang M,Wang S,Song Z
Tue Mar 01 00:00:00 EST 2022
MiR-146a-5p, targeting ErbB4, promotes 3T3-L1 preadipocyte differentiation through the ERK1/2/PPAR-γ signaling pathway.
Lipids in health and disease
Wang Y,Zhang J,Chu X,Wang M,Xin Y,Liu S
Wed Jun 15 00:00:00 EDT 2022
γ-mangostin attenuates amyloid-β42-induced neuroinflammation and oxidative stress in microglia-like BV2 cells via the mitogen-activated protein kinases signaling pathway.
European journal of pharmacology
Kong C,Jia L,Jia J
Tue Feb 15 00:00:00 EST 2022
High-Metastatic Melanoma Cells Promote the Metastatic Capability of Low-Metastatic Melanoma Cells via Exosomal Transfer of miR-411-5p.
Frontiers in oncology
Chen H,Zeng B,Li X,Zhao Q,Liu D,Chen Y,Zhang Y,Wang J,Xing HR
Sun Nov 05 00:00:00 EDT 2023
Discovery of Potent PROTACs Targeting EGFR Mutants through the Optimization of Covalent EGFR Ligands.
Journal of medicinal chemistry
Zhao HY,Wang HP,Mao YZ,Zhang H,Xin M,Xi XX,Lei H,Mao S,Li DH,Zhang SQ
Thu Mar 24 00:00:00 EDT 2022
ALG3 Promotes Peritoneal Metastasis of Ovarian Cancer through Increasing Interaction of α1,3-mannosylated uPAR and ADAM8.
Cells
Cui X,Pei X,Wang H,Feng P,Qin H,Liu S,Yan Q,Liu J
Thu Oct 06 00:00:00 EDT 2022
Oxidized high mobility group B-1 enhances metastability of colorectal cancer via modification of mesenchymal stem/stromal cells.
Cancer science
Kishi S,Fujiwara-Tani R,Honoki K,Sasaki R,Mori S,Ohmori H,Sasaki T,Miyagawa Y,Kawahara I,Kido A,Tanaka Y,Kuniyasu H
Mon Aug 01 00:00:00 EDT 2022
Suppression of AGTR1 Induces Cellular Senescence in Hepatocellular Carcinoma Through Inactivating ERK Signaling.
Frontiers in bioengineering and biotechnology
Wang H,Cui Y,Gong H,Xu J,Huang S,Tang A
Tue Aug 02 00:00:00 EDT 2022
Proteus mirabilis Vesicles Induce Mitochondrial Apoptosis by Regulating miR96-5p/Abca1 to Inhibit Osteoclastogenesis and Bone Loss.
Frontiers in immunology
Wang T,Mo L,Ou J,Fang Q,Wu H,Wu Y,Nandakumar KS
Mon May 02 00:00:00 EDT 2022
TDO2 modulates liver cancer cell migration and invasion via the Wnt5a pathway.
International journal of oncology
Liu H,Xiang Y,Zong QB,Dai ZT,Wu H,Zhang HM,Huang Y,Shen C,Wang J,Lu ZX,Ponnambalam S,Chen K,Wu Y,Zhang TC,Liao XH
Wed Jun 01 00:00:00 EDT 2022
Cholesterol promotes EGFR-TKIs resistance in NSCLC by inducing EGFR/Src/Erk/SP1 signaling-mediated ERRα re-expression.
Molecular cancer
Pan Z,Wang K,Wang X,Jia Z,Yang Y,Duan Y,Huang L,Wu ZX,Zhang JY,Ding X
Fri Mar 18 00:00:00 EDT 2022
Toxic effects of 4-methylimidazole on the maturation and fertilization of mouse oocytes.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Lu Y,Tang H,Xu J,Sun F
Wed Jun 01 00:00:00 EDT 2022
Tangeretin prevents cognitive deficit in delirium through activating RORα/γ-E4BP4 axis in mice.
Biochemical pharmacology
Chen M,Xiao Y,Zhang F,Du J,Zhang L,Li Y,Lu D,Wang Z,Wu B
Tue Nov 01 00:00:00 EDT 2022
Induction of COX-2 by feline calicivirus via activation of the MEK1-ERK1/2 pathway, and attenuation of feline lung inflammation and injury by MEK1 inhibitor AZD6244 (selumetinib).
Biochemical and biophysical research communications
Liu Y,Shi WD,Xie QQ,Wang JG,Gu CC,Ji ZH,Xiao J,Liu WQ
Sat May 14 00:00:00 EDT 2022
Non-Muscle MLCK Contributes to Endothelial Cell Hyper-Proliferation through the ERK Pathway as a Mechanism for Vascular Remodeling in Pulmonary Hypertension.
International journal of molecular sciences
Anis M,Gonzales J,Halstrom R,Baig N,Humpal C,Demeritte R,Epshtein Y,Jacobson JR,Fraidenburg DR
Mon Nov 07 00:00:00 EST 2022
CircFAT1 Promotes Lung Adenocarcinoma Progression by Sequestering miR-7 from Repressing IRS2-ERK-mediated CCND1 Expression.
International journal of biological sciences
Peng H,Zhang W,Dong H,Yuan J,Li Y,Li F,Yu D,Guan Y,Zhang F
Tue Jul 19 00:00:00 EDT 2022
CPSF1 mediates retinal vascular dysfunction in diabetes mellitus via the MAPK/ERK pathway.
Archives of physiology and biochemistry
Zhang J,Zhang X,Zou Y,Han F
Wed Jun 01 00:00:00 EDT 2022
Phycocyanin inhibits Helicobacter pylori-induced hyper-proliferation in AGS cells via activation of the ROS/MAPK signaling pathway.
Annals of translational medicine
Bi Y,Wu D,Wu X,Wang F,Yu H,Liu P,Cui G,Chen Z
Tue Feb 01 00:00:00 EST 2022
Investigation of cell cytotoxic activity and molecular mechanism of 5β,19-epoxycucurbita-6,23(E)-diene-3β,19(R),25-triol isolated from Momordica charantia on hepatoma cells.
Pharmaceutical biology
Yuan MK,Kao JW,Wu WT,Chen CR,Chang CI,Wu YJ
Thu Dec 01 00:00:00 EST 2022
Prenatal exposure to environmentally relevant levels of PBDE-99 leads to testicular dysgenesis with steroidogenesis disorders.
Journal of hazardous materials
Zhao T,Tang X,Li D,Zhao J,Zhou R,Shu F,Jia W,Fu W,Xia H,Liu G
Tue Feb 15 00:00:00 EST 2022
Renoprotective effects of levosimendan on acute kidney injury following cardiac arrest via anti-inflammation, anti-apoptosis, and ERK activation.
FEBS open bio
Tian L,Wang S,Zhao L,Lu X,Zhu C,Gong H,Yang W
Sun Aug 01 00:00:00 EDT 2021
Expression of Ubiquitin-specific protease 7 in oral squamous cell carcinoma promotes tumor cell proliferation and invasion.
Genetics and molecular biology
Yang X,Jin J,Yang J,Zhou L,Mi S,Qi G
Sat Dec 04 00:00:00 EST 2021
Low-dose repeated exposure to chemical surfactant impairs corneal epithelium: When personal cleaning products entering the eye.
Experimental eye research
Wu J,Wu T,Zheng S,Huang Y,Wang L
Wed Sep 01 00:00:00 EDT 2021
Myosin 1b promotes migration, invasion and glycolysis in cervical cancer via ERK/HIF-1α pathway.
American journal of translational research
Wen LJ,Hu XL,Li CY,Liu J,Li ZY,Li YZ,Zhou JY
Tue Dec 28 00:00:00 EST 2021
Vicenin-2 inhibits the Helicobacterium pylori infection associated gastric carcinogenic events through modulation of PI3K/AKT and Nrf2 signaling in GES-1 cells.
Journal of biochemical and molecular toxicology
Zhang Y,Sun J,Dong Y,Shen X,Zhang Z
Mon Mar 01 00:00:00 EST 2021
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Stem cells (Dayton, Ohio)
Luo L,Jian X,Sun H,Qin J,Wang Y,Zhang J,Shen Z,Yang D,Li C,Zhao P,Liu M,Tian Z,Zhou Y
Thu Apr 01 00:00:00 EDT 2021
G-Rh4 improves pancreatic β-cells dysfunction in vivo and in vitro by increased expression of Nrf2 and its target genes.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Liu Y,Deng J,Fan D
Mon Feb 01 00:00:00 EST 2021
Protective effects of dioscin against isoproterenol-induced cardiac hypertrophy via adjusting PKCε/ERK-mediated oxidative stress.
European journal of pharmacology
Li R,Qi Y,Yuan Q,Xu L,Gao M,Xu Y,Han X,Yin L,Liu C
Wed Sep 15 00:00:00 EDT 2021
Overexpression of PTPRN Promotes Metastasis of Lung Adenocarcinoma and Suppresses NK Cell Cytotoxicity.
Frontiers in cell and developmental biology
Song X,Jiao X,Yan H,Yu L,Jiang L,Zhang M,Chen L,Ju M,Wang L,Wei Q,Zhao L,Wei M
Sun Apr 24 00:00:00 EDT 2022
Serum proteome profiling provides a deep understanding of the 'gut-liver axis' in relation to liver injury and regeneration.
Acta biochimica et biophysica Sinica
Leng L,Ma J,Lv L,Gao D,Li M,Wang Y,Zhu Y
Tue Mar 02 00:00:00 EST 2021
A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.
Food science & nutrition
Zhou S,Zhou Y,Yu J,Jiang L,Xiang Y,Wang J,Du Y,Cui X,Ge F
Thu Jul 01 00:00:00 EDT 2021
Knockdown of ST6Gal-I expression in human hepatocellular carcinoma cells inhibits their exosome-mediated proliferation- and migration-promoting effects.
IUBMB life
Wang L,Chen X,Wang L,Wang S,Li W,Liu Y,Zhang J
Mon Nov 01 00:00:00 EDT 2021
PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell.
Frontiers in cardiovascular medicine
Li J,Wang C,Wang W,Liu L,Zhang Q,Zhang J,Wang B,Wang S,Hou L,Gao C,Yu X,Sun L
Fri Apr 02 00:00:00 EDT 2021
Myrtenol improves brain damage and promotes angiogenesis in rats with cerebral infarction by activating the ERK1/2 signalling pathway.
Pharmaceutical biology
Huang S,Tan Z,Cai J,Wang Z,Tian Y
Wed Dec 01 00:00:00 EST 2021
miR-483-3p Promotes IL-33 Production from Fibroblast-Like Synoviocytes by Regulating ERK Signaling in Rheumatoid Arthritis.
Inflammation
Zhang K,Fu W,Zhao S,Jiao T,Wu D,Wang Y
Wed Dec 01 00:00:00 EST 2021
The RNA-Binding Protein CELF2 Inhibits Ovarian Cancer Progression by Stabilizing FAM198B.
Molecular therapy. Nucleic acids
Guo Q,Wu Y,Guo X,Cao L,Xu F,Zhao H,Zhu J,Wen H,Ju X,Wu X
Fri Mar 05 00:00:00 EST 2021
Quercitrin Rapidly Alleviated Depression-like Behaviors in Lipopolysaccharide-Treated Mice: The Involvement of PI3K/AKT/NF-κB Signaling Suppression and CREB/BDNF Signaling Restoration in the Hippocampus.
ACS chemical neuroscience
Sun Y,Zhang H,Wu Z,Yu X,Yin Y,Qian S,Wang Z,Huang J,Wang W,Liu T,Xue W,Chen G
Wed Sep 15 00:00:00 EDT 2021
Berberine-photodynamic therapy sensitizes melanoma cells to cisplatin-induced apoptosis through ROS-mediated P38 MAPK pathways.
Toxicology and applied pharmacology
Wang X,Gong Q,Song C,Fang J,Yang Y,Liang X,Huang X,Liu J
Sat May 01 00:00:00 EDT 2021
Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor.
Molecules (Basel, Switzerland)
Ahmadu AA,Delehouzé C,Haruna A,Mustapha L,Lawal BA,Udobre A,Baratte B,Triscornia C,Autret A,Robert T,Bulinski JC,Rousselot M,Simoes Eugénio M,Dimanche-Boitrel MT,Petzer JP,Legoabe LJ,Bach S
Thu Jul 29 00:00:00 EDT 2021
The Role of Exercise in Reducing Hyperlipidemia-Induced Neuronal Damage in Apolipoprotein E-Deficient Mice.
BioMed research international
Bai Y,Feng Y,Jiang B,Yang Y,Pei Z,Yang Q,Cui Y
Tue Sep 28 00:00:00 EDT 2021
L-Theanine regulates glutamine metabolism and immune function by binding to cannabinoid receptor 1.
Food & function
Liu A,Lin L,Xu W,Gong Z,Liu Z,Xiao W
Mon Jul 05 00:00:00 EDT 2021
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Frontiers in pharmacology
Cai C,Hu W,Zhang Y,Hu X,Yang S,Qiu H,Wang R,Ma M,Qiu Y,Chu T
Tue Nov 23 00:00:00 EST 2021
Guifu Dihuang Pills Ameliorated Mucus Hypersecretion by Suppressing Muc5ac Expression and Inactivating the ERK-SP1 Pathway in Lipopolysaccharide/Cigarette Smoke-Induced Mice.
Evidence-based complementary and alternative medicine : eCAM
Zhang H,Yu W,Ji L,Zhong Y,Lin Y,Ying H,Yu C,Li C
Wed Nov 17 00:00:00 EST 2021
1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-κB/MAPK pathways.
European journal of medicinal chemistry
Tang JJ,Wang MR,Dong S,Huang LF,He QR,Gao JM
Mon Nov 15 00:00:00 EST 2021
MALAT-1 is Associated with the Doxorubicin Resistance in U-2OS Osteosarcoma Cells.
Cancer management and research
Liu C,Han X,Li B,Huang S,Zhou Z,Wang Z,Wang W
Tue Apr 26 00:00:00 EDT 2022
m6A Modification-Mediated DUXAP8 Regulation of Malignant Phenotype and Chemotherapy Resistance of Hepatocellular Carcinoma Through miR-584-5p/MAPK1/ERK Pathway Axis.
Frontiers in cell and developmental biology
Liu Z,Lu J,Fang H,Sheng J,Cui M,Yang Y,Tang B,Zhang X
Tue Dec 28 00:00:00 EST 2021
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Journal of ethnopharmacology
Zhou S,He Y,Zhang W,Xiong Y,Jiang L,Wang J,Cui X,Qu Y,Ge F
Tue Aug 10 00:00:00 EDT 2021
Knockdown of growth factor receptor bound protein 7 suppresses angiogenesis by inhibiting the secretion of vascular endothelial growth factor A in ovarian cancer cells.
Bioengineered
Xu Q,Liu Z,Zhu ZQ,Fan Y,Chen R,Xie XH,Cheng M
Wed Dec 01 00:00:00 EST 2021
An ionic lock and a hydrophobic zipper mediate the coupling between an insect pheromone receptor BmOR3 and downstream effectors.
The Journal of biological chemistry
Lin JY,Yang Z,Yang C,Du JX,Yang F,Cheng J,Pan W,Zhang SJ,Yan X,Wang J,Wang J,Tie L,Yu X,Chen X,Sun JP
Fri Oct 01 00:00:00 EDT 2021
Analysis and validation of m6A regulatory network: a novel circBACH2/has-miR-944/HNRNPC axis in breast cancer progression.
Journal of translational medicine
Lv W,Tan Y,Xiong M,Zhao C,Wang Y,Wu M,Wu Y,Zhang Q
Fri Dec 24 00:00:00 EST 2021
Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation.
Cell death & disease
Zhang Z,Mou Z,Xu C,Wu S,Dai X,Chen X,Ou Y,Chen Y,Yang C,Jiang H
Sat Aug 07 00:00:00 EDT 2021
Oridonin Promotes Apoptosis and Restrains the Viability and Migration of Bladder Cancer by Impeding TRPM7 Expression via the ERK and AKT Signaling Pathways.
BioMed research international
Che X,Zhan J,Zhao F,Zhong Z,Chen M,Han R,Wang Y
Thu Sep 23 00:00:00 EDT 2021
Omega-3 polyunsaturated fatty acids alleviate hydrogen sulfide-induced blood-testis barrier disruption in the testes of adult mice.
Reproductive toxicology (Elmsford, N.Y.)
Wang S,Chen Q,Zhang Y,Zheng F,Xue T,Ge X,Ma R,Li X,Wu R,Liang K,Qian Z,Ge Y,Ma J,Yao B
Tue Dec 01 00:00:00 EST 2020
Overexpression of Ubiquitin-Specific Protease 2 (USP2) in the Heart Suppressed Pressure Overload-Induced Cardiac Remodeling.
Mediators of inflammation
Xing J,Li P,Hong J,Wang M,Liu Y,Gao Y,Dong J,Gu H,Li L
Mon Aug 02 00:00:00 EDT 2021
IL-21 mediates microRNA-423-5p /claudin-5 signal pathway and intestinal barrier function in inflammatory bowel disease.
Aging
Wang M,Guo J,Zhao YQ,Wang JP
Fri Aug 28 00:00:00 EDT 2020
Thymoquinone Protects against Hyperlipidemia-Induced Cardiac Damage in Low-Density Lipoprotein Receptor-Deficient (LDL-R-/-) Mice via Its Anti-inflammatory and Antipyroptotic Effects.
BioMed research international
Pei ZW,Guo Y,Zhu HL,Dong M,Zhang Q,Wang F
Tue May 04 00:00:00 EDT 2021
Chemical characterization of a novel polysaccharide ASKP-1 from Artemisia sphaerocephala Krasch seed and its macrophage activation via MAPK, PI3k/Akt and NF-κB signaling pathways in RAW264.7 cells.
Food & function
Ren D,Lin D,Alim A,Zheng Q,Yang X
Wed Mar 22 00:00:00 EDT 2017
