Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 1
Phospho-ETK (Tyr40) Antibody (PA5-105185) in WB
Western blot analysis of Phospho-ETK (Tyr40) in Jurkat cell lysate (Lane 1: treated with phospho-blocking peptide; Lane 2: treated with non-phospho-blocking peptide). Samples were incubated with Phospho-ETK (Tyr40) polyclonal antibody (Product # PA5-105185).
Product Details
PA5-105185
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human BMX(Accession P51813), corresponding to amino acid residues around phosphorylated Tyr40.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2816658
Product Specific Information
Antibody detects endogenous levels of BMX only when phosphorylated at Tyr40.
Target Information
Bone marrow tyrosine kinase (BMX) is a non-receptor tyrosine kinase that belongs to the SRC-related TEC subfamily of tyrosine kinases. It is an important regulator of various cellular processes including apoptosis, cell survival, cellular differentiation, cell migration, and transformation. One family of nonreceptor TKs includes the genes TEC (MIM 600583), TXK (MIM 600058), ITK (MIM 186973), and BTK (MIM 300300). All of these proteins are homologs of the Drosophila Src28 TK and contain an SH3 and SH2 domain upstream of the TK domain.[supplied by OMIM].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Bone marrow tyrosine kinase gene in chromosome X protein; Bone marrow tyrosine kinase gene in chromosome X protein homolog; BTK-like on X chromosome; Cytoplasmic tyrosine-protein kinase BMX; epa3; Epithelial and endothelial tyrosine kinase; ETK; Etk/Bmx cytosolic tyrosine kinase; NTK38; NTK38 tyrosine kinase; TYRO8 protein tyrosine kinase 8
Gene Aliases: BMX; ETK; Etk/Bmx; PSCTK2; PSCTK3; Tyro8
UniProt ID: (Human) P51813, (Mouse) P97504
Entrez Gene ID: (Human) 660, (Mouse) 12169
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
signal transducer activity
receptor binding
protein binding
ATP binding
metal ion binding
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
GTPase-activating protein
NK T cell differentiation
protein phosphorylation
cellular component disassembly involved in execution phase of apoptosis
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
mesoderm development
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
innate immune response
protein autophosphorylation
adaptive immune response
apoptotic process
cell adhesion
phosphorylation
peptidyl-tyrosine phosphorylation
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support