Product References
Tumor Angiogenesis Is Differentially Regulated by Phosphorylation of Endothelial Cell Focal Adhesion Kinase Tyrosines-397 and -861.
Cancer research
Pedrosa AR,Bodrug N,Gomez-Escudero J,Carter EP,Reynolds LE,Georgiou PN,Fernandez I,Lees DM,Kostourou V,Alexopoulou AN,Batista S,Tavora B,Serrels B,Parsons M,Iskratsch T,Hodivala-Dilke KM
44-652G was used in Western Blotting to establish the differential requirements of EC-FAK-Y397 and EC-FAK-Y861-phosphorylation in the regulation of EC-signalling and tumor angiogenesis in vivo.
Sun Sep 01 00:00:00 EDT 2019
The PDGFRα-laminin B1-keratin 19 cascade drives tumor progression at the invasive front of human hepatocellular carcinoma.
Oncogene
Govaere O,Petz M,Wouters J,Vandewynckel YP,Scott EJ,Topal B,Nevens F,Verslype C,Anstee QM,Van Vlierberghe H,Mikulits W,Roskams T
Published figure using Phospho-FAK (Tyr576) polyclonal antibody (Product # 44-652G) in Western Blot
Thu Nov 23 00:00:00 EST 2017
A mutation in Nischarin causes otitis media via LIMK1 and NF-κB pathways.
PLoS genetics
Crompton M,Purnell T,Tyrer HE,Parker A,Ball G,Hardisty-Hughes RE,Gale R,Williams D,Dean CH,Simon MM,Mallon AM,Wells S,Bhutta MF,Burton MJ,Tateossian H,Brown SDM
Published figure using Phospho-FAK (Tyr576) polyclonal antibody (Product # 44-652G) in Western Blot
Tue Aug 01 00:00:00 EDT 2017
A Short Region of Connexin43 Reduces Human Glioma Stem Cell Migration, Invasion, and Survival through Src, PTEN, and FAK.
Stem cell reports
Jaraíz-Rodríguez M,Tabernero MD,González-Tablas M,Otero A,Orfao A,Medina JM,Tabernero A
44-652G was used in Western Blotting to show that a cell-penetrating peptide inhibited c-Src and focal adhesion kinase, and upregulated phosphatase and tensin homolog in glioma stem cells derived from patients.
Tue Aug 08 00:00:00 EDT 2017
Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition.
The Journal of cell biology
Horton ER,Humphries JD,Stutchbury B,Jacquemet G,Ballestrem C,Barry ST,Humphries MJ
44-652G was used in western blot to determine how modulation of FAK and Src adhesion signalling occurs without the need for adhesion complex composition
Mon Feb 01 00:00:00 EST 2016
Vinculin b deficiency causes epicardial hyperplasia and coronary vessel disorganization in zebrafish.
Development (Cambridge, England)
Cheng F,Miao L,Wu Q,Gong X,Xiong J,Zhang J
44652G was used in immunohistochemistry - paraffin section to determine the function of vinculin in zebrafish epicardium and endocardium
Sat Oct 01 00:00:00 EDT 2016
Tumor endothelial cells promote metastasis and cancer stem cell-like phenotype through elevated Epiregulin in esophageal cancer.
American journal of cancer research
Sun L,Pan J,Yu L,Liu H,Shu X,Sun L,Lou J,Yang Z,Ran Y
44652G was used in western blot to investigate the molecular mechanisms by which human esophageal cancer endothelial cells contribute to esophageal carcinoma progression
Wed Mar 16 00:00:00 EDT 2022
Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling.
Nature communications
Robertson J,Jacquemet G,Byron A,Jones MC,Warwood S,Selley JN,Knight D,Humphries JD,Humphries MJ
44-652G was used in western blot to study phosphorylation events at sites of adhesion
Fri Feb 13 00:00:00 EST 2015
Pelargonidin attenuates PDGF-BB-induced aortic smooth muscle cell proliferation and migration by direct inhibition of focal adhesion kinase.
Biochemical pharmacology
Son JE,Jeong H,Kim H,Kim YA,Lee E,Lee HJ,Lee KW
44-652G was used in western blot to study the preventive effects of pelargonidin toward atherosclerosis mechanistically.
Thu May 15 00:00:00 EDT 2014
LCB 03-0110, a novel pan-discoidin domain receptor/c-Src family tyrosine kinase inhibitor, suppresses scar formation by inhibiting fibroblast and macrophage activation.
The Journal of pharmacology and experimental therapeutics
Sun X,Phan TN,Jung SH,Kim SY,Cho JU,Lee H,Woo SH,Park TK,Yang BS
Thu Mar 01 00:00:00 EST 2012
Enhanced integrin mediated signaling and cell cycle progression on fibronectin mimetic peptide amphiphile monolayers.
Langmuir : the ACS journal of surfaces and colloids
Shroff K,Pearce TR,Kokkoli E
44-652G was used in western blot to study the binding affinity of the PR_b peptide ligand with the α(5)β() integrin.
Tue Jan 24 00:00:00 EST 2012
Enhanced integrin mediated signaling and cell cycle progression on fibronectin mimetic peptide amphiphile monolayers.
Langmuir : the ACS journal of surfaces and colloids
Shroff K,Pearce TR,Kokkoli E
44-652G was used in western blot to study the binding affinity of the PR_b peptide ligand with the α(5)β() integrin.
Tue Jan 24 00:00:00 EST 2012
Activation of endogenous FAK via expression of its amino terminal domain in Xenopus embryos.
PloS one
Petridou NI,Stylianou P,Christodoulou N,Rhoads D,Guan JL,Skourides PA
Thu Jan 10 00:00:00 EST 2013
Activation of endogenous FAK via expression of its amino terminal domain in Xenopus embryos.
PloS one
Petridou NI,Stylianou P,Christodoulou N,Rhoads D,Guan JL,Skourides PA
Thu Jan 10 00:00:00 EST 2013
Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion.
Molecular and cellular biology
Tsygankova OM,Ma C,Tang W,Korch C,Feldman MD,Lv Y,Brose MS,Meinkoth JL
44-652G was used in western blot to elucidate the benefits of loss of Rap1GAP in cancer cells
Thu Jul 01 00:00:00 EDT 2010
Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion.
Molecular and cellular biology
Tsygankova OM,Ma C,Tang W,Korch C,Feldman MD,Lv Y,Brose MS,Meinkoth JL
44-652G was used in western blot to elucidate the benefits of loss of Rap1GAP in cancer cells
Thu Jul 01 00:00:00 EDT 2010
Arrestin-3 is essential for the activation of Fyn by the luteinizing hormone receptor (LHR) in MA-10 cells.
Cellular signalling
Galet C,Ascoli M
44-652G was used in western blot to identify signaling molecules involve in LHR-provoked activation of Fyn
Wed Oct 01 00:00:00 EDT 2008
Alphavbeta3 integrin and cofilin modulate K1735 melanoma cell invasion.
Experimental cell research
Dang D,Bamburg JR,Ramos DM
44-652G was used in western blot to explore the relationship between beta3-integrin expression, phosphorylation of cofilin, and metalloproteinase production
Wed Feb 15 00:00:00 EST 2006
Analyzing FAK and Pyk2 in early integrin signaling events.
Current protocols in cell biology
Bernard-Trifilo JA,Lim ST,Hou S,Schlaepfer DD,Ilic D
Sat Apr 01 00:00:00 EST 2006
Analyzing FAK and Pyk2 in early integrin signaling events.
Current protocols in cell biology
Bernard-Trifilo JA,Lim ST,Hou S,Schlaepfer DD,Ilic D
Sat Apr 01 00:00:00 EST 2006
SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading.
Molecular and cellular biology
Cary LA,Klinghoffer RA,Sachsenmaier C,Cooper JA
Mon Apr 01 00:00:00 EST 2002
SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading.
Molecular and cellular biology
Cary LA,Klinghoffer RA,Sachsenmaier C,Cooper JA
Mon Apr 01 00:00:00 EST 2002
FAK integrates growth-factor and integrin signals to promote cell migration.
Nature cell biology
Sieg DJ,Hauck CR,Ilic D,Klingbeil CK,Schaefer E,Damsky CH,Schlaepfer DD
Mon May 01 00:00:00 EDT 2000
FAK integrates growth-factor and integrin signals to promote cell migration.
Nature cell biology
Sieg DJ,Hauck CR,Ilic D,Klingbeil CK,Schaefer E,Damsky CH,Schlaepfer DD
Mon May 01 00:00:00 EDT 2000
FAK integrates growth-factor and integrin signals to promote cell migration.
Nature cell biology
Sieg DJ,Hauck CR,Ilic D,Klingbeil CK,Schaefer E,Damsky CH,Schlaepfer DD
Mon May 01 00:00:00 EDT 2000
FAK integrates growth-factor and integrin signals to promote cell migration.
Nature cell biology
Sieg DJ,Hauck CR,Ilic D,Klingbeil CK,Schaefer E,Damsky CH,Schlaepfer DD
Mon May 01 00:00:00 EDT 2000