Invitrogen

Phospho-Histone H3 (Ser10) Polyclonal Antibody

Advanced Verification

This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.

16 Published Figures

29 References

View all (196) Histone H3 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Phospho-Histone H3 (Ser10) Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 26

Phospho-Histone H3 (Ser10) Antibody (PA5-17869) in ICC/IF

Immunofluorescence analysis of Phospho-Histone H3 (ser 10) was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Phospho-Histone H3 (Ser10) Rabbit Polyclonal antibody (Product # PA5-17869) at 1:100 dilution i... View More

Phospho-Histone H3 (Ser10) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Phospho-Histone H3 (Ser10) Antibody in Western Blot (WB)

Phospho-Histone H3 (Ser10) Antibody in Flow Cytometry (Flow)

Phospho-Histone H3 (Ser10) Antibody in Peptide array (Array)

Phospho-Histone H3 (Ser10) Antibody in Immunocytochemistry, Immunohistochemistry (ICC/IF, IHC)

Phospho-Histone H3 (Ser10) Antibody in Western Blot, Immunocytochemistry (WB, ICC/IF)

Phospho-Histone H3 (Ser10) Antibody in Immunohistochemistry (IHC)

Phospho-Histone H3 (Ser10) Antibody in Immunohistochemistry, Immunohistochemistry (PFA fixed) (IHC, IHC (PFA))

Phospho-Histone H3 (Ser10) Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

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Product Details

PA5-17869

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 7 publications 7 publications

Immunohistochemistry (IHC)

View 11 publications 11 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200

Immunohistochemistry (PFA fixed) (IHC (PFA))

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

1:400

Immunocytochemistry (ICC/IF)

1:800

View 9 publications 9 publications

Flow Cytometry (Flow)

1:50

View 1 publication 1 publication

Peptide Array (Array)

1:2,000

Product Specifications

Species Reactivity

Fruit fly, Human, Mouse, Non-human primate, Rat, Xenopus

Published species

C. elegans, Chicken, Fruit fly, Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pSer10 of human histone H3

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 100µg/mL BSA, 0.15M NaCl, 50% glycerol

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10984484

Product Specific Information

Phospho-Histone H3 (Ser10) Antibody detects endogenous levels of histone H3 only when phosphorylated at Ser10; however, this antibody does not detect phosphorylated Ser10 when Lys9 is acetylated or methylated. This antibody does not cross-react with histone H3 phosphorylated at Ser28.

This antibody is not cross-reactive with other phosphorylated histones or with acetylated histones.

Target Information

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Dbx2, an Aging-Related Homeobox Gene, Inhibits the Proliferation of Adult Neural Progenitors.

Stem cell reviews and reports

Giuliani A,Licursi V,Nisi PS,Fiore M,D'Angelo S,Biagioni S,Negri R,Rugg-Gunn PJ,Cacci E,Lupo G

PA5-17869 was used in Immunocytochemistry-immunofluorescence to point to Dbx2 as a transcription factor relaying the anti-neurogenic input of the aged niche to the neural/stem progenitor cell transcriptome.

Wed Nov 01 00:00:00 EDT 2023

Elevated 18:0 lysophosphatidylcholine contributes to the development of pain in tissue injury.

Pain

Friston DA,Cuddihy J,Souza Luiz J,Truong AH,Ho L,Basra M,Santha P,Oszlacs O,de Sousa Valente J,Marczylo T,Junttila S,Laycock H,Collins D,Vizcaychipi M,Gyenesei A,Takats Z,Jancso G,Want E,Nagy I

PA5-17869 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Peptide array, Western Blot to report that, amongst other important metabolite changes, lysophosphatidylcholines (LPCs) including 18:0 LPC exhibit significant and consistent local burn injury-induced changes in concentration.

Wed Feb 01 00:00:00 EST 2023

Inhibition of DYRK1A, via histone modification, promotes cardiomyocyte cell cycle activation and cardiac repair after myocardial infarction.

EBioMedicine

Lan C,Chen C,Qu S,Cao N,Luo H,Yu C,Wang N,Xue Y,Xia X,Fan C,Ren H,Yang Y,Jose PA,Xu Z,Wu G,Zeng C

PA5-17869 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Peptide array, Western Blot to reveal a significant role of DYRK1A in cardiac repair and suggest a drug target with translational potential for treating cardiomyopathy.

Mon Aug 01 00:00:00 EDT 2022

'Shared-Hook' and 'Changed-Hook' Binding Activities of Herpesviral Core Nuclear Egress Complexes Identified by Random Mutagenesis.

Cells

Lösing J,Häge S,Schütz M,Wagner S,Wardin J,Sticht H,Marschall M

PA5-17869 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Peptide array, Western Blot to provide improved insights into herpesviral nuclear egress complex (NEC) protein binding specificities of core NEC formation.

Tue Dec 13 00:00:00 EST 2022

Proteomic analysis reveals USP7 as a novel regulator of palmitic acid-induced hepatocellular carcinoma cell death.

Cell death & disease

Saha S,Verma R,Kumar C,Kumar B,Dey AK,Surjit M,Mylavarapu SVS,Maiti TK

PA5-17869 was used in Flow cytometry/Cell sorting to provide evidence of PA-induced hepatocellular death mediated by deubiquitinase USP7 downregulation and subsequent mitotic catastrophe.

Wed Jun 22 00:00:00 EDT 2022

Regorafenib Induces Senescence and Epithelial-Mesenchymal Transition in Colorectal Cancer to Promote Drug Resistance.

Cells

Kehagias P,Kindt N,Krayem M,Najem A,Agostini G,Acedo Reina E,Bregni G,Sclafani F,Journe F,Awada A,Ghanem GE,Hendlisz A

PA5-17869 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Peptide array, Western Blot to use an early senescence state to undergo EMT.

Fri Nov 18 00:00:00 EST 2022

Altered Gut Structure and Anti-Bacterial Defense in Adult Mice Treated with Antibiotics during Early Life.

Antibiotics (Basel, Switzerland)

Martins Garcia T,van Roest M,Vermeulen JLM,Meisner S,Koster J,Wildenberg ME,van Elburg RM,Muncan V,Renes IB

PA5-17869 was used in Immunohistochemistry to suggest that early life AB leads to structural and physiological changes in the adult gut, which may contribute to disease development when homeostatic conditions are under challenge.

Fri Feb 18 00:00:00 EST 2022

The exocyst complex regulates C. elegans germline stem cell proliferation by controlling membrane Notch levels.

Development (Cambridge, England)

Pushpa K,Dagar S,Kumar H,Pathak D,Mylavarapu SVS

PA5-17869 was used in Immunohistochemistry to reveal that the exocyst complex regulates C. elegans GSC proliferation by modulating Notch signaling cell autonomously.

Sun Aug 01 00:00:00 EDT 2021

MicroRNA Signatures of the Developing Primate Fovea.

Frontiers in cell and developmental biology

Fishman ES,Louie M,Miltner AM,Cheema SK,Wong J,Schlaeger NM,Moshiri A,Simó S,Tarantal AF,La Torre A

PA5-17869 was used in Immunohistochemistry to identify several miRNAs differentially expressed in the presumptive fovea, including miR-15b-5p, miR-342-5p, miR-30b-5p, miR-103-3p, miR-93-5p as well as the miRNA cluster miR-183/-96/-182.

Sat Jul 16 00:00:00 EDT 2022

Translation of Tudor-SN, a novel terminal oligo-pyrimidine (TOP) mRNA, is regulated by the mTORC1 pathway in cardiomyocytes.

RNA biology

Gan S,Su C,Ma J,Liu M,Cui X,Xin L,Ren Y,Gao X,Ge L,Wei M,Yang J

PA5-17869 was used in Immunocytochemistry to suggest that the translational efficiency of Tudor-SN is regulated by the mTORC1 pathway in myocardia and that Tudor-SN is involved in mTORC1-mediated regulation of cardiomyocytic proliferation and cardiac development.

Tue Jun 01 00:00:00 EDT 2021

Human Taste Cells Express ACE2: a Portal for SARS-CoV-2 Infection.

bioRxiv : the preprint server for biology

Doyle ME,Appleton A,Liu QR,Yao Q,Mazucanti CH,Egan JM

PA5-17869 was used in Immunohistochemistry to investigate whether ACE2 is expressed on taste receptor cells (TRCs) nor if TRCs are infected directly.

Wed Apr 21 00:00:00 EDT 2021

Human Taste Cells Express ACE2: a Portal for SARS-CoV-2 Infection.

bioRxiv : the preprint server for biology

Doyle ME,Appleton A,Liu QR,Yao Q,Mazucanti CH,Egan JM

PA5-17869 was used in Immunohistochemistry to investigate whether ACE2 is expressed on taste receptor cells (TRCs) nor if TRCs are infected directly.

Wed Apr 21 00:00:00 EDT 2021

Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis.

PLoS genetics

Pizzo L,Lasser M,Yusuff T,Jensen M,Ingraham P,Huber E,Singh MD,Monahan C,Iyer J,Desai I,Karthikeyan S,Gould DJ,Yennawar S,Weiner AT,Pounraja VK,Krishnan A,Rolls MM,Lowery LA,Girirajan S

PA5-17869 was used in Western Blot to suggest that several 16p12.1 genes sensitize the genome towards neurodevelopmental defects, and complex interactions with "second-hit" genes determine the ultimate phenotypic manifestation.

Thu Apr 01 00:00:00 EDT 2021

Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis.

PLoS genetics

Pizzo L,Lasser M,Yusuff T,Jensen M,Ingraham P,Huber E,Singh MD,Monahan C,Iyer J,Desai I,Karthikeyan S,Gould DJ,Yennawar S,Weiner AT,Pounraja VK,Krishnan A,Rolls MM,Lowery LA,Girirajan S

Thu Apr 01 00:00:00 EDT 2021

Human Type II Taste Cells Express Angiotensin-Converting Enzyme 2 and Are Infected by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).

The American journal of pathology

Doyle ME,Appleton A,Liu QR,Yao Q,Mazucanti CH,Egan JM

PA5-17869 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Peptide array, Western Blot to demonstrate the possibility that novel and sudden taste changes, frequently reported in COVID-19, may be the result of direct infection of taste papillae by SARS-CoV-2.

Wed Sep 01 00:00:00 EDT 2021

Progesterone, via yes-associated protein, promotes cardiomyocyte proliferation and cardiac repair.

Cell proliferation

Lan C,Cao N,Chen C,Qu S,Fan C,Luo H,Zeng A,Yu C,Xue Y,Ren H,Li L,Wang H,Jose PA,Xu Z,Zeng C

PA5-17869 was used in Western Blotting to uncover a role of circulating progesterone withdrawal as a novel mechanism for the postnatal loss of mammalian cardiac regenerative potential.

Sun Nov 01 00:00:00 EDT 2020

Progesterone, via yes-associated protein, promotes cardiomyocyte proliferation and cardiac repair.

Cell proliferation

Lan C,Cao N,Chen C,Qu S,Fan C,Luo H,Zeng A,Yu C,Xue Y,Ren H,Li L,Wang H,Jose PA,Xu Z,Zeng C

PA5-17869 was used in Western Blotting to uncover a role of circulating progesterone withdrawal as a novel mechanism for the postnatal loss of mammalian cardiac regenerative potential.

Sun Nov 01 00:00:00 EDT 2020

Progesterone, via yes-associated protein, promotes cardiomyocyte proliferation and cardiac repair.

Cell proliferation

Lan C,Cao N,Chen C,Qu S,Fan C,Luo H,Zeng A,Yu C,Xue Y,Ren H,Li L,Wang H,Jose PA,Xu Z,Zeng C

PA5-17869 was used in Western Blotting to uncover a role of circulating progesterone withdrawal as a novel mechanism for the postnatal loss of mammalian cardiac regenerative potential.

Sun Nov 01 00:00:00 EDT 2020

Progesterone, via yes-associated protein, promotes cardiomyocyte proliferation and cardiac repair.

Cell proliferation

Lan C,Cao N,Chen C,Qu S,Fan C,Luo H,Zeng A,Yu C,Xue Y,Ren H,Li L,Wang H,Jose PA,Xu Z,Zeng C

PA5-17869 was used in Western Blotting to uncover a role of circulating progesterone withdrawal as a novel mechanism for the postnatal loss of mammalian cardiac regenerative potential.

Sun Nov 01 00:00:00 EDT 2020

Agrin Promotes Limbal Stem Cell Proliferation and Corneal Wound Healing Through Hippo-Yap Signaling Pathway.

Investigative ophthalmology & visual science

Hou L,Fu W,Liu Y,Wang Q,Wang L,Huang Y

PA5-17869 was used in Western Blotting to show how agrin promotes the proliferation of limbal stem cells and accelerates the healing rate of cornceal would through Hippo-Yap signalling pathway.

Mon May 11 00:00:00 EDT 2020

Agrin Promotes Limbal Stem Cell Proliferation and Corneal Wound Healing Through Hippo-Yap Signaling Pathway.

Investigative ophthalmology & visual science

Hou L,Fu W,Liu Y,Wang Q,Wang L,Huang Y

PA5-17869 was used in Western Blotting to show how agrin promotes the proliferation of limbal stem cells and accelerates the healing rate of cornceal would through Hippo-Yap signalling pathway.

Mon May 11 00:00:00 EDT 2020

FZD5 contributes to TNBC proliferation, DNA damage repair and stemness.

Cell death & disease

Sun Y,Wang Z,Na L,Dong D,Wang W,Zhao C

PA5-17869 was used in Immunohistochemistry to show that FZD5 is a novel target for the development of therapeutic strategies to overcome chemoresistance and prevent recurrence in TNBC.

Sat Dec 12 00:00:00 EST 2020

FZD5 contributes to TNBC proliferation, DNA damage repair and stemness.

Cell death & disease

Sun Y,Wang Z,Na L,Dong D,Wang W,Zhao C

PA5-17869 was used in Immunohistochemistry to show that FZD5 is a novel target for the development of therapeutic strategies to overcome chemoresistance and prevent recurrence in TNBC.

Sat Dec 12 00:00:00 EST 2020

Loss of FOXF1 expression promotes human lung-resident mesenchymal stromal cell migration via ATX/LPA/LPA1 signaling axis.

Scientific reports

Cao P,Walker NM,Braeuer RR,Mazzoni-Putman S,Aoki Y,Misumi K,Wheeler DS,Vittal R,Lama VN

PA5-17869 was used in Western Blotting to identify FOXF1 as a novel transcriptional repressor of ATX and demonstrate that loss of FOXF1 promotes LR-MSC migration via the ATX/LPA/LPA1 signalling axis.

Fri Dec 04 00:00:00 EST 2020

Loss of FOXF1 expression promotes human lung-resident mesenchymal stromal cell migration via ATX/LPA/LPA1 signaling axis.

Scientific reports

Cao P,Walker NM,Braeuer RR,Mazzoni-Putman S,Aoki Y,Misumi K,Wheeler DS,Vittal R,Lama VN

PA5-17869 was used in Western Blotting to identify FOXF1 as a novel transcriptional repressor of ATX and demonstrate that loss of FOXF1 promotes LR-MSC migration via the ATX/LPA/LPA1 signalling axis.

Fri Dec 04 00:00:00 EST 2020

Mud Loss Restricts Yki-Dependent Hyperplasia in Drosophila Epithelia.

Journal of developmental biology

Parra AS,Johnston CA

PA5-17869 was used in Immunohistochemistry-immunofluorescence to suggest that ECM/BM remodeling can limit untoward growth initiated by an important driver of tumor growth and highlight a potential regulatory link with cytoskeleton-associated genes.

Sun Dec 13 00:00:00 EST 2020

Mud Loss Restricts Yki-Dependent Hyperplasia in Drosophila Epithelia.

Journal of developmental biology

Parra AS,Johnston CA

Sun Dec 13 00:00:00 EST 2020

OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome.

Cell stem cell

Xu R,Brawner AT,Li S,Liu JJ,Kim H,Xue H,Pang ZP,Kim WY,Hart RP,Liu Y,Jiang P

PA5-17869 was used in Western Blotting to conclude that altered OLIG2 expression may underlie neurodevelopmental abnormalities and cognitive defects in DS patients.

Thu Jun 06 00:00:00 EDT 2019

Ceramide: a novel inducer for neural tube defects.

Developmental dynamics : an official publication of the American Association of Anatomists

Ross MM,Piorczynski TB,Harvey J,Burnham TS,Francis M,Larsen MW,Roe K,Hansen JM,Stark MR

PA5-17869 was used in Immunohistochemistry to conclude that increased ROS generation in cell culture, along with the more oxidative GSH E h profiles of C2 exposed cells and embryos, support a model wherein ceramide affects neural tube closure via altered tissue redox environments.

Tue Oct 01 00:00:00 EDT 2019

Dynamics and Spatial Genomics of the Nascent Transcriptome by Intron seqFISH.

Cell

Shah S,Takei Y,Zhou W,Lubeck E,Yun J,Eng CL,Koulena N,Cronin C,Karp C,Liaw EJ,Amin M,Cai L

PA5-17869 was used in Immunocytochemistry-immunoflourescence to conclude that spatial genomics of the nascent transcriptome by intron seqFISH reveals nuclear organizational principles and fast dynamics in single cells that are otherwise obscured.

Thu Jul 12 00:00:00 EDT 2018

Aurora A kinase activity is required to maintain an active spindle assembly checkpoint during prometaphase.

Journal of cell science

Courtheoux T,Diallo A,Damodaran AP,Reboutier D,Watrin E,Prigent C

PA5-17869 was used in Western Blotting to report that inhibition of Aurora A leads to loss of the spindle assembly checkpoint even in the presence of nocodazole or Taxol.

Thu Apr 12 00:00:00 EDT 2018

RAD52 is required for RNA-templated recombination repair in post-mitotic neurons.

The Journal of biological chemistry

Welty S,Teng Y,Liang Z,Zhao W,Sanders LH,Greenamyre JT,Rubio ME,Thathiah A,Kodali R,Wetzel R,Levine AS,Lan L

Published figure using Phospho-Histone H3 (Ser10) polyclonal antibody (Product # PA5-17869) in Immunocytochemistry

Fri Jan 26 00:00:00 EST 2018

RAD52 is required for RNA-templated recombination repair in post-mitotic neurons.

The Journal of biological chemistry

Welty S,Teng Y,Liang Z,Zhao W,Sanders LH,Greenamyre JT,Rubio ME,Thathiah A,Kodali R,Wetzel R,Levine AS,Lan L

Published figure using Phospho-Histone H3 (Ser10) polyclonal antibody (Product # PA5-17869) in Immunocytochemistry

Fri Jan 26 00:00:00 EST 2018

A sleep state in Drosophila larvae required for neural stem cell proliferation.

eLife

Szuperak M,Churgin MA,Borja AJ,Raizen DM,Fang-Yen C,Kayser MS

PA5-17869 was used in Immunohistochemistry to identify a sleep state in Drosophila larvae as a critical factor for normal proliferation of neural stem cells.

Fri Feb 09 00:00:00 EST 2018

Autophagy protects ovarian cancer-associated fibroblasts against oxidative stress.

Cell cycle (Georgetown, Tex.)

Wang Q,Xue L,Zhang X,Bu S,Zhu X,Lai D

PA5-17869 was used in immunocytochemistry and western blot to investigate protection of ovarian cancer-associated fibroblasts against oxidative stress by autophagy

Wed May 18 00:00:00 EDT 2016

Autophagy protects ovarian cancer-associated fibroblasts against oxidative stress.

Cell cycle (Georgetown, Tex.)

Wang Q,Xue L,Zhang X,Bu S,Zhu X,Lai D

PA5-17869 was used in immunocytochemistry and western blot to investigate protection of ovarian cancer-associated fibroblasts against oxidative stress by autophagy

Wed May 18 00:00:00 EDT 2016

Bioinformatics

Protein Aliases: CG31613-PA; H3 histone family, member A; H3 histone family, member I; H3 histone family, member J; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3-clustered histone 13; H3-clustered histone 14; H3-clustered histone 15; H3-clustered histone 2; H3-clustered histone 3; H3-clustered histone 4; H3-clustered histone 6; H3-clustered histone 7; H3/b; H3/d; H3/f; H3/j; H3S10ph; His3:CG31613-PA; histone 1, H3a; histone 1, H3b; histone 1, H3f; histone 1, H3h; histone 1, H3j; histone 2, H3a; histone 2, H3c; histone 2, H3c2; histone 2, H3ca2; Histone 3; histone cluster 1, H3a; Histone Cluster 2 H3a; histone cluster 2, H3c2, pseudogene; histone cluster 3, H3; histone gene complex 1; Histone H3; Histone H3.1; Histone H3.2; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; Histone H3/m; Histone H3/o

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Gene Aliases: CG31613; CG33803; CG33806; CG33809; CG33812; CG33815; CG33818; CG33821; CG33824; CG33827; CG33830; CG33833; CG33836; CG33839; CG33842; CG33845; CG33848; CG33851; CG33854; CG33857; CG33860; CG33863; CG33866; Dmel\CG31613; Dmel_CG31613; H3; H3-143; H3-291; H3-53; H3-614; H3-B; H3-F; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; h3.2a; H3/A; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3a; H3b; H3C1; H3C10; H3C11; H3C12; H3C13; H3C14; H3C15; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3F1K; H3F2; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; h3r; His3; His3:CG31613; His3:CG33803; His3:CG33806; His3:CG33809; His3:CG33812; His3:CG33815; His3:CG33818; His3:CG33821; His3:CG33824; His3:CG33827; His3:CG33830; His3:CG33833; His3:CG33836; His3:CG33839; His3:CG33842; His3:CG33845; His3:CG33848; His3:CG33851; His3:CG33854; His3:CG33857; His3:CG33860; His3:CG33863; His3:CG33866; Hist1; HIST1H3A; HIST1H3B; Hist1h3c; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; hist2h3; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; Hist2h3ca2; HIST2H3D; M32461; XELAEV_18028537mg

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UniProt ID: (Human) P68431, (Human) Q71DI3, (Fruit fly) P02299, (Mouse) P68433, (Mouse) P84228, (Mouse) Q8CGN9

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Entrez Gene ID: (Human) 8350, (Human) 8358, (Human) 8968, (Human) 8357, (Human) 8356, (Human) 333932, (Human) 126961, (Fruit fly) 318847, (Mouse) 360198, (Rat) 679994, (Mouse) 319150, (Mouse) 260423, (Mouse) 319152, (Mouse) 97114, (Xenopus) 399088

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Function(s)

DNA binding protein binding histone binding protein heterodimerization activity cadherin binding involved in cell-cell adhesion nucleosomal DNA binding histone

Process(es)

chromatin silencing at rDNA positive regulation of defense response to virus by host nucleosome assembly DNA replication-dependent nucleosome assembly blood coagulation gene silencing by RNA telomere organization cellular protein metabolic process negative regulation of gene expression, epigenetic positive regulation of gene expression, epigenetic protein heterotetramerization regulation of gene silencing cell-cell adhesion xenophagy

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Phospho-Histone H3 (Ser10) Polyclonal Antibody

Phospho-Histone H3 (Ser10) Antibody (PA5-17869) in ICC/IF

Product Details

PA5-17869

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunohistochemistry (Frozen) (IHC (F))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Peptide Array (Array)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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