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Invitrogen
Phospho-eIF4G (Ser1108) Recombinant Rabbit Monoclonal Antibody (PS01-08)
FIGURE: 1 / 2
Phospho-eIF4G (Ser1108) Antibody (MA5-50782) in ICC/IF
Immunocytochemistry analysis of Phospho-eIF4G (Ser1108) in A431 cells. Cells were fixed in 4% paraformaldehyde for 10 minutes at 37 , permeabilized with 0.05% Triton X-100 in PBS for 20 minutes, and then blocked with 2% negative goat serum for 30 minutes at room temperature. Cells were incubated with Phospho-eIF4G (Ser1108) recombinant monoclonal antibody (Product # MA5-50782) with a dilution of 1:50 in 2% ... View More
Product Details
MA5-50782
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
PS01-08
Immunogen
Synthetic peptide corresponding to Human eIF4G1 aa 1181-1230/1599 (phospho S1108).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3092910
Product Specific Information
Positive control: A431 cell lysate, SK-Br-3 cell lysate, MCF-7 cell lysate, A431.
Predicted band size: 175 kDa
Subcellular Location: Cytosol Nucleus.
Target Information
The protein encoded by this gene is a component of the protein complex EIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure, and recruitment of mRNA to the ribosome. Alternative splicing results in five transcript variants encoding four distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp686A1451; eIF-4-gamma 1; EIF4-gamma; eucaryotic translation initiation factor 4G; Eukaryotic translation initiation factor 4 gamma 1; eukaryotic translation initiation factor 4 gamma, 1; OTTHUMP00000210577; OTTHUMP00000210586; OTTHUMP00000210587; OTTHUMP00000210588; OTTHUMP00000210595; OTTHUMP00000210602; OTTHUMP00000210603; p220
Gene Aliases: EIF-4G1; EIF4F; EIF4G; EIF4G1; EIF4GI; P220; PARK18
UniProt ID: (Human) Q04637
Entrez Gene ID: (Human) 1981
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
nuclear-transcribed mRNA poly(A) tail shortening
behavioral fear response
translational initiation
regulation of translational initiation
viral process
regulation of mRNA stability
positive regulation of neuron differentiation
cell-cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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