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Product Details
68250-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
4A3C7
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: SPSPSPSPSQ NATQTTTDSS NKTAPTPASS VTIMATDTAQ QSTVPTSKAN EILASVKATT LGVSSDSPGT TTLAQQVSGP VNTTVARGGG SGNPTTTIES PKSTKSADTT TVATSTATAK PNTTSSQNGA EDTTNSGGKS SHSVTTDLTS TKAEHLTTPH PTSPLSPRQP TSTHPVATPT SSGHDHLMKI SSSSSTVAIP GYTFTSPGMT TTLPSSVISQ RTQQTSSQMP ASSTAPSSQE TVQPTSPATA LRTPTLPETM SSSPTAASTT HRYPKTPSPT VAHESNWAKC EDLETQTQSE KQLVLNLTGN TLCAGGASDE KLISLICRAV KATFNPAQDK CGIRLASVPG SQTVVVKEIT IHTKLPAKDV YERLKDKWDE LKEAGVSDMK LGDQGPPEEA EDRFSM
Target Information
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GCTM-2 antigen; Gp200; MGC138240; PC; PCLP antibody; PCLP1 antibody; PODLX2; Podocalyxin; podocalyxin-like; Podocalyxin-like protein 1; podolyxin
Gene Aliases: Gp200; PC; PCLP; PCLP-1; PCLP1; PODXL
UniProt ID: (Human) O00592
Entrez Gene ID: (Human) 5420
cell adhesion
negative regulation of cell adhesion
cell migration
negative regulation of cell-cell adhesion
positive regulation of cell migration
regulation of microvillus assembly
positive regulation of cell-cell adhesion mediated by integrin
leukocyte migration
glomerular visceral epithelial cell development
epithelial tube formation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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