Invitrogen

Progesterone Receptor Monoclonal Antibody (Alpha PR6)

Advanced Verification

This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.

16 Published Figures

46 References

View all (149) Progesterone Receptor antibodies

Datasheet

Protocols

Questions & Answers

Tech Support

Datasheet

Protocols

Questions & Answers

Tech Support

Progesterone Receptor Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 21

Progesterone Receptor Antibody (MA1-411) in ICC/IF

Immunofluorescent analysis of Progesterone Receptor (green) in T47D cells untreated (left) or stimulated with 100nm promegestone, R5020, for 1 hour (right). The cells were fixed with formalin for 15 minutes, permeabilized with 0.1% Triton X-100 in TBS for 10 minutes, and blocked with 3% Blocker BSA (Product # 37525) for 15 minutes at room temperature. Cells were stained with Progesterone Receptor mouse mono... View More

Progesterone Receptor Antibody in Immunohistochemistry (IHC)

Progesterone Receptor Antibody in Western Blot (WB)

Product Image Gallery

Product Details

MA1-411

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 35 publications 35 publications

Immunohistochemistry (Paraffin) (IHC (P))

5 µg/mL

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

20 µg/mL

Immunocytochemistry (ICC/IF)

Assay-dependent

View 5 publications 5 publications

Immunoprecipitation (IP)

Assay-dependent

View 1 publication 1 publication

ChIP assay (ChIP)

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Bovine, Chicken, Guinea pig, Human, Mouse, Sheep, Rabbit, Rat

Published species

Camelid, Chicken, Human, Mouse, Non-human primate, Rat, Sheep

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

Alpha PR6

Immunogen

Progesterone receptor purified from chick oviduct cytosol.

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2283820

Product Specific Information

MA1-411 reacts with high affinity to the B form of the progesterone receptor from human, mouse, rat, rabbit, bovine, ovine, chicken, and guinea pig tissues. This antibody does not cross-react with estrogen receptor or glucocorticoid receptor.

MA1-411 has been successfully used in Western blot, immunocytochemical, immunohistochemical and immunoprecipitation procedures. By Western blot, this antibody detects a 110 kDa protein representing the B form of the PR in chickens."

The MA1-411 immunogen is progesterone receptor purified from chick oviduct cytosol.

Reconstitute with PBS.

Target Information

The progesterone receptor (PR) is a member of the steroid family of nuclear receptors. The PR mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. PR is found as a 94 kDa protein (Form A) or a 120 kDa protein (Form B) due to the use of alternative translation initiation sites. PR-B is the transcriptionally active form and is responsible for activating genes for the maintenance of the endometrium, maintenance of pregnancy, and inhibition of ovulation. PR-A is identical to PR-B except for a 165 amino acid deletion at the N-terminus. This deletion exposes a 140 amino acid inhibitory domain (ID) that acts as a repressor of steroid hormone transcriptional activity. In its inactive state, PgR forms a multiprotein complex which includes heat shock proteins and immunophins. Upon binding of progesterone hormone to its receptor, there is a conformational change that allows dimerization and binding of the receptor to progesterone response elements (PRE) sequences, resulting in activated transcription. A Null mutation in the PGR gene leads to pleiotrophic reproductive abnormalities.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Progesterone prevents HGSOC by promoting precancerous cell pyroptosis via inducing fibroblast paracrine.

iScience

Wu N,Zhang X,Wang Z,Zhang X,Fang C,Li H,Zhu M,Wang Y,Liao Q,Chu TY,Wang J

MA1-411 was used in Immunohistochemistry to demonstrated that progesterone significantly inhibited the occurrence, metastasis, and ascites of ovarian cancer in vivo, and the tumor inhibition effect of progesterone was in the tubo-ovarian intrabursal model than in the intraperitoneal or subcutaneous models.

Fri Apr 21 00:00:00 EDT 2023

Inhibition of CXorf56 promotes PARP inhibitor-induced cytotoxicity in triple-negative breast cancer.

NPJ breast cancer

Zhu Y,Liu Z,Gui L,Yun W,Mao C,Deng R,Yao Y,Yu Q,Feng J,Ma H,Bao W

MA1-411 was used in Immunohistochemistry to indicate that treatment designed to inhibit CXorf56 protein in TNBC combined with PARPis may overcome drug resistance and expand the application of PARPis to patients with non-BRCA mutantion.

Mon May 08 00:00:00 EDT 2023

Enhanced anti-cancer effects of oestrogen and progesterone co-therapy against colorectal cancer in males.

Frontiers in endocrinology

Mahbub AA,Aslam A,Elzubier ME,El-Boshy M,Abdelghany AH,Ahmad J,Idris S,Almaimani R,Alsaegh A,El-Readi MZ,Baghdadi MA,Refaat B

Published figure using Progesterone Receptor monoclonal antibody (Product # MA1-411) in Immunohistochemistry

Fri Oct 21 00:00:00 EDT 2022

Pre-implantation exogenous progesterone and pregnancy in sheep: I. polyamines, nutrient transport, and progestamedins.

Journal of animal science and biotechnology

Hoskins EC,Halloran KM,Stenhouse C,Moses RM,Dunlap KA,Satterfield MC,Seo H,Johnson GA,Wu G,Bazer FW

MA1-411 was used in Immunohistochemistry to examine the effects of exogenous progesterone on the expression of major genes involved in the arginine-agmatine-polyamine pathway, extending previous knowledge on nutrient transport and molecular signaling during the peri-implantation period, and how mechanisms responsible for advancing morphological development of ovine conceptuses are affected.

Fri Mar 05 00:00:00 EST 2021

Pre-implantation exogenous progesterone and pregnancy in sheep: I. polyamines, nutrient transport, and progestamedins.

Journal of animal science and biotechnology

Hoskins EC,Halloran KM,Stenhouse C,Moses RM,Dunlap KA,Satterfield MC,Seo H,Johnson GA,Wu G,Bazer FW

Fri Mar 05 00:00:00 EST 2021

Macrophages in bovine term placenta: An ultrastructural and molecular study.

Reproduction in domestic animals = Zuchthygiene

Hooshmandabbasi R,Kazemian A,Zerbe H,Kowalewski MP,Klisch K

Published figure using Progesterone Receptor monoclonal antibody (Product # MA1-411) in Immunocytochemistry

Wed Sep 01 00:00:00 EDT 2021

Macrophages in bovine term placenta: An ultrastructural and molecular study.

Reproduction in domestic animals = Zuchthygiene

Hooshmandabbasi R,Kazemian A,Zerbe H,Kowalewski MP,Klisch K

Published figure using Progesterone Receptor monoclonal antibody (Product # MA1-411) in Immunocytochemistry

Wed Sep 01 00:00:00 EDT 2021

Levels of sex steroid hormones and their receptors in women with preeclampsia.

Reproductive biology and endocrinology : RB&E

Lan KC,Lai YJ,Cheng HH,Tsai NC,Su YT,Tsai CC,Hsu TY

MA1-411 was used in Western Blot to compare patients with preeclampsia and patients with uncomplicated pregnancies in terms of serum steroid hormones throughout pregnancy and the levels of cord blood and placental steroid receptors during the third trimester.

Tue Feb 18 00:00:00 EST 2020

NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer.

NPJ breast cancer

Dischinger PS,Tovar EA,Essenburg CJ,Madaj ZB,Gardner EE,Callaghan ME,Turner AN,Challa AK,Kempston T,Eagleson B,Kesterson RA,Bronson RT,Bowman MJ,Graveel CR,Steensma MR

MA1-411 was used in Immunohistochemistry to evaluate the effect of Nf1 deficiency on tumourigenesis.

Thu Oct 01 00:00:00 EDT 2020

Lack of cortistatin or somatostatin differentially influences DMBA-induced mammary gland tumorigenesis in mice in an obesity-dependent mode.

Breast cancer research : BCR

Luque RM,Villa-Osaba A,L-López F,Pozo-Salas AI,Sánchez-Sánchez R,Ortega-Salas R,de Lecea L,Álvarez-Benito M,López-Miranda J,Gahete MD,Castaño JP

MA1-411 was used in immunohistochemistry - paraffin section to discuss the roles of somatostatin and cortistatin in mammary gland tumorigenesis and metabolic disorders

Tue Mar 08 00:00:00 EST 2016

Progesterone and Wnt4 control mammary stem cells via myoepithelial crosstalk.

The EMBO journal

Rajaram RD,Buric D,Caikovski M,Ayyanan A,Rougemont J,Shan J,Vainio SJ,Yalcin-Ozuysal O,Brisken C

MA1-411 was used in immunohistochemistry - paraffin section to study the role of progesterone on global stem cell function by serially transplanting mouse mammary epithelia

Wed Mar 04 00:00:00 EST 2015

No direct nuclear effect of progesterone in the inner ear: other possible pathways.

Acta oto-laryngologica

Bonnard A,Sahlin L,Hultcrantz M,Simonoska R

MA1-411 was used in immunohistochemistry to investigate the lack of progesterone receptor expression in rat and human inner ear

Sun Dec 01 00:00:00 EST 2013

Endometrial population of oestrogen receptors alpha and beta and progesterone receptors A and B during the different phases of the follicular wave of llamas (Lama glama).

Reproduction in domestic animals = Zuchthygiene

Bianchi C,Sahlin L,Meikle A,Masironi B,Cavilla M,Aba M

MA1-411 was used in immunohistochemistry to investigate the expression level of population of oestrogen receptors alpha and beta and progesterone receptors A and B in endometrial cell population

Fri Oct 01 00:00:00 EDT 2010

Conditional deletion of the Lkb1 gene in the mouse mammary gland induces tumour formation.

The Journal of pathology

McCarthy A,Lord CJ,Savage K,Grigoriadis A,Smith DP,Weigelt B,Reis-Filho JS,Ashworth A

MA1-411 was used in immunohistochemistry to develop a mouse model of Lkb1 deficiency to study its role in mammary tumorigenesis

Sun Nov 01 00:00:00 EDT 2009

A composite intronic element directs dynamic binding of the progesterone receptor and GATA-2.

Molecular endocrinology (Baltimore, Md.)

Magklara A,Smith CL

MA1-411 was used in chromatin immunoprecipitation to study the role of progesterone receptor in mammary gland development and mammary tumorigenesis.

Thu Jan 01 00:00:00 EST 2009

Prostaglandin treatment is associated with a withdrawal of progesterone and androgen at the receptor level in the uterine cervix.

Reproductive biology and endocrinology : RB&E

Vladic-Stjernholm Y,Vladic T,Blesson CS,Ekman-Ordeberg G,Sahlin L

MA1-411 was used in immunohistochemistry to investigate the mechanism of the prostaglandin treatment for cervical priming

Fri Oct 23 00:00:00 EDT 2009

Steroid receptor expression and morphology in provoked vestibulodynia.

American journal of obstetrics and gynecology

Johannesson U,Sahlin L,Masironi B,Hilliges M,Blomgren B,Rylander E,Bohm-Starke N

MA1-411 was used in immunohistochemistry to investigate the expression of steroid receptor in vulvar vestibular mucosa

Sat Mar 01 00:00:00 EST 2008

Effects of tibolone and conventional HRT on the expression of estrogen and progesterone receptors in the breast.

Maturitas

Ma L,Hofling M,Masironi B,von Schoultz B,Cline JM,Sahlin L

MA1-411 was used in immunohistochemistry to study the effects of tibolone and conventional hormone replacement therapy on mammary expression of estrogen and progesterone receptors

Sat Dec 20 00:00:00 EST 2008

Effects of testosterone and estrogen treatment on the distribution of sex hormone receptors in the endometrium of postmenopausal women.

Menopause (New York, N.Y.)

Zang H,Sahlin L,Masironi B,Hirschberg AL

MA1-411 was used in immunohistochemistry to examine the effects of testosterone and estrogen on sex hormone receptor expresssion in endometrial glands and stroma of postmenopausal women

Wed Jul 09 00:00:00 EDT 2008

A mouse model of basal-like breast carcinoma with metaplastic elements.

The Journal of pathology

McCarthy A,Savage K,Gabriel A,Naceur C,Reis-Filho JS,Ashworth A

MA1-411 was used in immunohistochemistry to develop a mouse model of basal-like breast carcinoma with metaplastic elements

Thu Mar 01 00:00:00 EST 2007

Pelvic floor sex steroid hormone receptors, distribution and expression in pre- and postmenopausal stress urinary incontinent women.

Acta obstetricia et gynecologica Scandinavica

Söderberg MW,Johansson B,Masironi B,Byström B,Falconer C,Sahlin L,Ordeberg GE

MA1-411 was used in immunohistochemistry to investigate the expression of sex steroid hormone receptors in the pelvic floor ECM in pre- and postmenopausal women with and without stress urinary incontinence

Thu Dec 13 00:00:00 EST 2007

Steroid receptor expression in the vulvar vestibular mucosa--effects of oral contraceptives and menstrual cycle.

Contraception

Johannesson U,Sahlin L,Masironi B,Rylander E,Bohm-Starke N

MA1-411 was used in immunohistochemistry to study the expression of steroid receptor in the vulvar vestibular mucosa after the intake of oral contraceptives and during menstrual cycle

Mon Oct 01 00:00:00 EDT 2007

Overlapping and distinct expression of progesterone receptors A and B in mouse uterus and mammary gland during the estrous cycle.

Endocrinology

Mote PA,Arnett-Mansfield RL,Gava N,deFazio A,Mulac-Jericevic B,Conneely OM,Clarke CL

MA1-411 was used in Immunohistochemistry to show nonoverlapping progesterone receptor A and B expression in the uterus.

Fri Dec 01 00:00:00 EST 2006

Progesterone regulation of preimplantation conceptus growth and galectin 15 (LGALS15) in the ovine uterus.

Biology of reproduction

Satterfield MC,Bazer FW,Spencer TE

MA1-411 was used in immunohistochemistry to investigate early progesterone's influence on blastocyst growth and secreted proteins' endometrial level

Tue Aug 01 00:00:00 EDT 2006

Characterization of ovarian surface epithelial cells from the hen: a unique model for ovarian cancer.

Experimental biology and medicine (Maywood, N.J.)

Giles JR,Olson LM,Johnson PA

MA1-411 was used in immunocytochemistry to characterize the ovarian surface epithelial cells in the hen with ovarian cancer

Fri Dec 01 00:00:00 EST 2006

Oestrogen receptor alpha and beta, androgen receptor and progesterone receptor mRNA and protein localisation within the developing ovary and in small growing follicles of sheep.

Reproduction (Cambridge, England)

Juengel JL,Heath DA,Quirke LD,McNatty KP

MA1-411 was used in immunohistochemistry to study the expression of progesterone receptor localisation within the developing ovary and in small growing follicles of sheep

Sun Jan 01 00:00:00 EST 2006

FK506-binding protein 52 is essential to uterine reproductive physiology controlled by the progesterone receptor A isoform.

Molecular endocrinology (Baltimore, Md.)

Yang Z,Wolf IM,Chen H,Periyasamy S,Chen Z,Yong W,Shi S,Zhao W,Xu J,Srivastava A,Sánchez ER,Shou W

MA1-411 was used in immunoprecipitation to study the role of FKBP52 in progesterone receptor action.

Wed Nov 01 00:00:00 EST 2006

FK506-binding protein 52 is essential to uterine reproductive physiology controlled by the progesterone receptor A isoform.

Molecular endocrinology (Baltimore, Md.)

Yang Z,Wolf IM,Chen H,Periyasamy S,Chen Z,Yong W,Shi S,Zhao W,Xu J,Srivastava A,Sánchez ER,Shou W

MA1-411 was used in immunoprecipitation to study the role of FKBP52 in progesterone receptor action.

Wed Nov 01 00:00:00 EST 2006

Tissue- and hormone-dependent progesterone receptor distribution in the rat uterus.

Reproductive biology and endocrinology : RB&E

Sahlin L,Masironi B,Akerberg S,Eriksson H

MA1-411 was used in immunohistochemistry to study the localization of PR in the rat uterus under various hormonal conditions

Mon Sep 11 00:00:00 EDT 2006

Myometrial effects of selective estrogen receptor modulators on estradiol-responsive gene expression are gene and cell-specific.

The Journal of steroid biochemistry and molecular biology

Farnell YZ,Ing NH

MA1-411 was used in immunohistochemistry to investigate the effect of selective estrogen receptor modulators on estradiol-responsive gene expression

Tue Apr 01 00:00:00 EST 2003

Endometrial effects of selective estrogen receptor modulators (SERMs) on estradiol-responsive gene expression are gene and cell-specific.

The Journal of steroid biochemistry and molecular biology

Farnell YZ,Ing NH

MA1-411 was used in immunohistochemistry to study the modality of the effects of estrogen receptor modulators estradiol-responsive gene expression in endometria

Tue Apr 01 00:00:00 EST 2003

Effects of long-term HRT and tamoxifen on the expression of progesterone receptors A and B in breast tissue from surgically postmenopausal cynomolgus macaques.

Breast cancer research and treatment

Isaksson E,Wang H,Sahlin L,von Schoultz B,Cline JM,von Schoultz E

MA1-411 was used in immunohistochemistry to study the effect of hormonal and tamoxifen treatment on progesterone receptors A and B in breast tissue

Thu May 01 00:00:00 EDT 2003

Development and characterization of an endometrial tissue culture system.

Reproductive biomedicine online

Stavreus-Evers A,Hovatta O,Eriksson H,Landgren BM

MA1-411 was used in immunohistochemistry to develop a system for the culture of whole pieces of endometrium

Mon Sep 01 00:00:00 EDT 2003

Postpartum uterine involution in sheep: histoarchitecture and changes in endometrial gene expression.

Reproduction (Cambridge, England)

Gray CA,Stewart MD,Johnson GA,Spencer TE

MA1-411 was used in immunohistochemistry to investigate the effect of postpartum uterine involution in sheep

Sat Feb 01 00:00:00 EST 2003

Effect of long-term treatment with steroid hormones or tamoxifen on the progesterone receptor and androgen receptor in the endometrium of ovariectomized cynomolgus macaques.

Reproductive biology and endocrinology : RB&E

Wang H,Isaksson E,von Schoultz B,Cline JM,Sahlin L

MA1-411 was used in immunohistochemistry to investigate the effect of long-term treatment with steroid hormones or tamoxifen on the progesterone receptor and androgen receptor in the endometrium of ovariectomized cynomolgus macaques

Wed Feb 05 00:00:00 EST 2003

Expression of progesterone receptors A and B and insulin-like growth factor-I in human myometrium and fibroids after treatment with a gonadotropin-releasing hormone analogue.

Fertility and sterility

Wu X,Wang H,Englund K,Blanck A,Lindblom B,Sahlin L

MA1-411 was used in immunohistochemistry to study the effects of a gonadotrophin-releasing hormone on the expression of progesterone receptors A and B and IGF-1 in human myometrium and fibroids

Fri Nov 01 00:00:00 EST 2002

Formation of pinopodes in human endometrium is associated with the concentrations of progesterone and progesterone receptors.

Fertility and sterility

Stavreus-Evers A,Nikas G,Sahlin L,Eriksson H,Landgren BM

MA1-411 was used in immunohistochemistry to study the relationship between the development of human endometrial pinopodes and the levels of progesterone, progesterone receptors and estrogen receptors

Mon Oct 01 00:00:00 EDT 2001

Progesterone modulation of osteopontin gene expression in the ovine uterus.

Biology of reproduction

Johnson GA,Spencer TE,Burghardt RC,Taylor KM,Gray CA,Bazer FW

MA1-411 was used in immunocytochemistry to study how the expression of OPN gene is regulated and the corresponding protein secretion by GE in the ovine uterus

Mon May 01 00:00:00 EDT 2000

Neonatal ovine uterine development involves alterations in expression of receptors for estrogen, progesterone, and prolactin.

Biology of reproduction

Taylor KM,Gray CA,Joyce MM,Stewart MD,Bazer FW,Spencer TE

MA1-411 was used in immunohistochemistry to study the changes of expression of estrogen receptor, progesterone receptor and prolactin receptor during neonatal ovine uterine development

Sun Oct 01 00:00:00 EDT 2000

Interferon-tau and progesterone regulate ubiquitin cross-reactive protein expression in the ovine uterus.

Biology of reproduction

Johnson GA,Spencer TE,Burghardt RC,Joyce MM,Bazer FW

MA1-411 was used in immunocytochemistry to investigate the possible role of progesterone in IFN-tau-induced UCRP expression within the ovine uterus

Wed Mar 01 00:00:00 EST 2000

Ovine uterine gland knock-out model: effects of gland ablation on the estrous cycle.

Biology of reproduction

Allison Gray C,Bartol FF,Taylor KM,Wiley AA,Ramsey WS,Ott TL,Bazer FW,Spencer TE

MA1-411 was used in immunohistochemistry to investigate the effects of gland ablation on the estrous cycle in ovine uterine gland knock-out model

Tue Feb 01 00:00:00 EST 2000

Effects of recombinant ovine interferon tau, placental lactogen, and growth hormone on the ovine uterus.

Biology of reproduction

Spencer TE,Gray A,Johnson GA,Taylor KM,Gertler A,Gootwine E,Ott TL,Bazer FW

MA1-411 was used in immunohistochemistry to study the effects of recombinant ovine interferon tau, placental lactogen, and growth hormone on endometrial function

Wed Dec 01 00:00:00 EST 1999

Estradiol up-regulates estrogen receptor and progesterone receptor gene expression in specific ovine uterine cells.

Biology of reproduction

Ing NH,Tornesi MB

MA1-411 was used in immunohistochemistry to investigate the influence of estradiol on specific gene expression in ovine uterine cells

Thu May 01 00:00:00 EDT 1997

Progesterone-induced avidin as a marker of cytodifferentiation in the oviduct: comparison to ovalbumin.

Endocrinology

Joensuu TK,Ylikomi TJ,Toft DO,Keinanen RA,Kulomaa MS,Tuohimaa PJ

MA1-411 was used in immunohistochemistry to investigate avidin expression in the oviduct

Thu Feb 01 00:00:00 EST 1990

Progesterone receptor concentration differences in the chick oviduct cells and apparent down-regulation by ligand. A semiquantitative immunohistochemical study.

Journal of steroid biochemistry

Pekki A,Joensuu T,Vidqvist K,Toft D,Tuohimaa P

MA1-411 was used in immunohistochemistry to investigate the expression of progesterone receptor in the chick oviduct

Fri Mar 30 00:00:00 EST 1990

Immunocytochemical study of progesterone receptors in hyperplastic and neoplastic endometrial tissues.

Cancer research

Bergeron C,Ferenczy A,Toft DO,Shyamala G

MA1-411 was used in immunohistochemistry to investigate the expression and distribution of progesterone receptors in hyperplastic and neoplastic human endometrium

Tue Nov 01 00:00:00 EST 1988

Immunocytochemical study of progesterone receptors in the human endometrium during the menstrual cycle.

Laboratory investigation; a journal of technical methods and pathology

Bergeron C,Ferenczy A,Toft DO,Schneider W,Shyamala G

MA1-411 was used in immunocytochemistry to investigate the changes of progesterone receptors expression in the endometrium during the menstrual cycle

Thu Dec 01 00:00:00 EST 1988

Bioinformatics

Protein Aliases: Nuclear receptor subfamily 3 group C member 3; pot. alt. progesterone receptor; putative; PR; Progesterone receptor; progesterone receptor A; progesterone-receptor; steroid hormone receptor; unnamed protein product

View more View less

Gene Aliases: 9930019P03Rik; BB114106; ENSMUSG00000074510; NR3C3; PGR; PR; PR-A; PR-B

View more View less

UniProt ID: (Rabbit) P06186, (Chicken) Q90946, (Human) P06401, (Rat) Q63449, (Mouse) Q00175

View more View less

Entrez Gene ID: (Sheep) 443444, (Rabbit) 100009094, (Bovine) 100848466, (Chicken) 396198, (Human) 5241, (Rat) 25154, (Guinea pig) 100724945, (Mouse) 18667

View more View less

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding zinc ion binding enzyme binding Hsp70 protein binding chromatin DNA binding sequence-specific DNA binding Hsp90 protein binding steroid hormone binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding steroid binding protein binding ATPase binding receptor binding hormone binding lipid binding metal ion binding

Process(es)

ovulation from ovarian follicle luteinization epithelial cell maturation transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter positive regulation of cell proliferation negative regulation of gene expression positive regulation of smooth muscle cell migration diterpenoid metabolic process intracellular receptor signaling pathway mammary gland development response to progesterone response to cocaine negative regulation of apoptotic process steroid hormone mediated signaling pathway response to estrogen estrous cycle negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter regulation of epithelial cell proliferation progesterone receptor signaling pathway female mating behavior tertiary branching involved in mammary gland duct morphogenesis cellular response to gonadotropin stimulus cellular response to follicle-stimulating hormone stimulus cellular response to luteinizing hormone stimulus intracellular steroid hormone receptor signaling pathway transcription initiation from RNA polymerase II promoter signal transduction cell-cell signaling paracrine signaling lung alveolus development

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

Progesterone Receptor Monoclonal Antibody (Alpha PR6)

Progesterone Receptor Antibody (MA1-411) in ICC/IF

Product Details

MA1-411

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (Frozen) (IHC (F))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

ChIP assay (ChIP)

Miscellaneous PubMed (Misc)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!