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Alomone Labs, LTD
Prostaglandin F2- alpha Receptor/PTGFR Polyclonal Antibody
FIGURE: 1 / 2
Prostaglandin F2- alpha Receptor/PTGFR Antibody (APR-067-200UL) in IHC (F)
Expression of Prostaglandin F2-alpha receptor in mouse hippocampus - Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-Prostaglandin F2- alpha Receptor/PTGFR Antibody (#APR-067) (1:200), followed by goat Anti-rabbit-AlexaFluor-488. PTGFR staining (green) in mouse hippocampal dentate gyrus is detected in cell bodies (arrows). Cell nuclei are stained with DAPI (blue). Mouse... View More
Product Details
APR-067-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)RSQQHRQGRSHHLE, corresponding to amino acid residues 233-246 of rat Prostaglandin F2- alpha Receptor, 3rd intracellular loop
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PGF receptor; PGF2 alpha receptor; PGF2-alpha receptor; prostaglandin F receptor (FP); prostaglandin F2 alpha receptor; Prostaglandin F2-alpha receptor; prostaglandin F2alpha receptor; prostaglandin receptor (2-alpha); Prostanoid FP receptor
Gene Aliases: AI957154; FP; PF2AR; PGF; PTGFR
UniProt ID: (Human) P43088, (Rat) P43118, (Mouse) P43117
Entrez Gene ID: (Human) 5737, (Rat) 25652, (Mouse) 19220
inflammatory response
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
parturition
positive regulation of cell proliferation
positive regulation of gene expression
response to estradiol
response to lipopolysaccharide
calcium-mediated signaling using intracellular calcium source
negative regulation of apoptotic process
cellular response to prostaglandin D stimulus
signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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