Product References
SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1.
Cell death and differentiation
Sun X,Liu Y,Huang Z,Xu W,Hu W,Yi L,Liu Z,Chan H,Zeng J,Liu X,Chen H,Yu J,Chan FKL,Ng SC,Wong SH,Wang MH,Gin T,Joynt GM,Hui DSC,Zou X,Shu Y,Cheng CHK,Fang S,Luo H,Lu J,Chan MTV,Zhang L,Wu WKK
R930-25 was used in Western Blot to support that NSP6 of SARS-CoV-2 could induce inflammatory cell death in lung epithelial cells, through which pharmacological rectification of autophagic flux might be therapeutically exploited.
Wed Jun 01 00:00:00 EDT 2022
C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus.
iScience
Wu Y,Mahtal N,Paillares E,Swistak L,Sagadiev S,Acharya M,Demeret C,Werf SV,Guivel-Benhassine F,Schwartz O,Petracchini S,Mettouchi A,Caramelle L,Couvineau P,Thai R,Barbe P,Keck M,Brodin P,Machelart A,Sencio V,Trottein F,Sachse M,Chicanne G,Payrastre B,Ville F,Kreis V,Popoff MR,Johannes L,Cintrat JC,Barbier J,Gillet D,Lemichez E
R930-25 was used in Immunocytochemistry-immunoflourescence to identify a small chemical compound, C910, that protects host cells against eight different bacterial AB toxins.
Fri Jul 15 00:00:00 EDT 2022
Exposed CendR Domain in Homing Peptide Yields Skin-Targeted Therapeutic in Epidermolysis Bullosa.
Molecular therapy : the journal of the American Society of Gene Therapy
Pemmari T,Ivanova L,May U,Lingasamy P,Tobi A,Pasternack A,Prince S,Ritvos O,Makkapati S,Teesalu T,Cairo MS,Järvinen TAH,Liao Y
R930-25 was used in Immunohistochemistry to demonstrate that removal of the cysteine from CRK to expose the CendR sequence confers the peptide novel ability to home to normal skin.
Wed Aug 05 00:00:00 EDT 2020
Exposed CendR Domain in Homing Peptide Yields Skin-Targeted Therapeutic in Epidermolysis Bullosa.
Molecular therapy : the journal of the American Society of Gene Therapy
Pemmari T,Ivanova L,May U,Lingasamy P,Tobi A,Pasternack A,Prince S,Ritvos O,Makkapati S,Teesalu T,Cairo MS,Järvinen TAH,Liao Y
R930-25 was used in Immunohistochemistry to demonstrate that removal of the cysteine from CRK to expose the CendR sequence confers the peptide novel ability to home to normal skin.
Wed Aug 05 00:00:00 EDT 2020
Multicomponent gold nano-glycoconjugate as a highly immunogenic and protective platform against Burkholderia mallei.
NPJ vaccines
Tapia D,Sanchez-Villamil JI,Torres AG
R930-25 was used in Western Blotting to provide the basis for the rational design and construction of a multicomponent vaccine platform against Burkholderia mallei (Bm).
Tue Jul 04 00:00:00 EDT 2023
Multicomponent gold nano-glycoconjugate as a highly immunogenic and protective platform against Burkholderia mallei.
NPJ vaccines
Tapia D,Sanchez-Villamil JI,Torres AG
R930-25 was used in Western Blotting to provide the basis for the rational design and construction of a multicomponent vaccine platform against Burkholderia mallei (Bm).
Tue Jul 04 00:00:00 EDT 2023
Bi- and tri-valent T cell engagers deplete tumour-associated macrophages in cancer patient samples.
Journal for immunotherapy of cancer
Scott EM,Jacobus EJ,Lyons B,Frost S,Freedman JD,Dyer A,Khalique H,Taverner WK,Carr A,Champion BR,Fisher KD,Seymour LW,Duffy MR
Published figure using 6x-His Tag monoclonal antibody (Product # R930-25) in Western Blot
Thu Nov 21 00:00:00 EST 2019
A multiplatform strategy for the discovery of conventional monoclonal antibodies that inhibit the voltage-gated potassium channel Kv1.3.
mAbs
Bednenko J,Harriman R,Mariën L,Nguyen HM,Agrawal A,Papoyan A,Bisharyan Y,Cardarelli J,Cassidy-Hanley D,Clark T,Pedersen D,Abdiche Y,Harriman W,van der Woning B,de Haard H,Collarini E,Wulff H,Colussi P
R930-25 was used in Western Blotting to develop a multiplatform strategy for the discovery of conventional monoclonal antibodies that inhibit the voltage-gated potassium channel Kv1.3.
Mon Aug 12 00:00:00 EDT 2019
De novo designed transmembrane peptides activating the α5β1 integrin.
Protein engineering, design & selection : PEDS
Mravic M,Hu H,Lu Z,Bennett JS,Sanders CR,Orr AW,DeGrado WF
R930-25 was used in Western Blotting to characterize novel CHAMP peptides activating α5Β1 that can serve as useful reagents for probing integrin biology.
Tue May 01 00:00:00 EDT 2018
A peptide tag-specific nanobody enables high-quality labeling for dSTORM imaging.
Nature communications
Virant D,Traenkle B,Maier J,Kaiser PD,Bodenhöfer M,Schmees C,Vojnovic I,Pisak-Lukáts B,Endesfelder U,Rothbauer U
R930-25 was used in Western Blotting to develop a peptide tag-specific labelling strategy for dSTORM imaging, applicable in both fixed and living cells.
Fri Mar 02 00:00:00 EST 2018
Broad cross-reactive IgG responses elicited by adjuvanted vaccination with recombinant influenza hemagglutinin (rHA) in ferrets and mice.
PloS one
Wang J,Hilchey SP,DeDiego M,Perry S,Hyrien O,Nogales A,Garigen J,Amanat F,Huertas N,Krammer F,Martinez-Sobrido L,Topham DJ,Treanor JJ,Sangster MY,Zand MS
R930-25 was used in Luminex assays to examine the antibody response to adjuvanted vaccination with recombinant influenza haemagglutinin in ferrets and mice.
Thu Jul 12 00:00:00 EDT 2018
Randomized CRISPR-Cas Transcriptional Perturbation Screening Reveals Protective Genes against Alpha-Synuclein Toxicity.
Molecular cell
Chen YC,Farzadfard F,Gharaei N,Chen WCW,Cao J,Lu TK
R930-25 was used in Western Blotting to demonstrate that perturbation of transcriptional networks via randomized CRISPR-Cas transcription factors can reveal complex biological phenotypes and effective disease modulators.
Thu Oct 05 00:00:00 EDT 2017
ΔNp73 overexpression promotes resistance to apoptosis but does not cooperate with PML/RARA in the induction of an APL-leukemic phenotype.
Oncotarget
Lucena-Araujo AR,Coelho-Silva JL,Pereira-Martins DA,Thomé C,Scheucher PS,Lange AP,Paiva HH,Hemmelgarn BT,Morais-Sobral MC,Azevedo EA,Franca-Neto PL,Franca RF,Silva CL,Krause A,Rego EM
R93025 was used in western blot to examine if the overexpression of transcriptionally inactive DeltaNp73 cooperates with PML/RARA fusion protein in the induction of an APL-leukemic phenotype
Tue Jan 31 00:00:00 EST 2017
Bioengineered human heparin with anticoagulant activity.
Metabolic engineering
Lord MS,Cheng B,Tang F,Lyons JG,Rnjak-Kovacina J,Whitelock JM
R93025 was used in ELISA to synthesize and characterize heparin-like heparan sulfate in human cells
Tue Nov 01 00:00:00 EDT 2016
The Tumor Antigen NY-ESO-1 Mediates Direct Recognition of Melanoma Cells by CD4+ T Cells after Intercellular Antigen Transfer.
Journal of immunology (Baltimore, Md. : 1950)
Fonteneau JF,Brilot F,Münz C,Gannagé M
R93025 was used in immunocytochemistry to elucidate how NY-ESO-1 is processed onto MHC class II molecules for direct CD4+ T cell recognition of melanoma cells
Fri Jan 01 00:00:00 EST 2016
High rates of glucose utilization in the gas gland of Atlantic cod (Gadus morhua) are supported by GLUT1 and HK1b.
The Journal of experimental biology
Clow KA,Short CE,Hall JR,Gendron RL,Paradis H,Ralhan A,Driedzic WR
R93025 was used in immunohistochemistry - frozen section to study glucose utilization in the gas gland of Atlantic cod
Thu Sep 01 00:00:00 EDT 2016
Synthetic chimeras with orthogonal ribosomal proteins increase translation yields by recruiting mRNA for translation as measured by profiling active ribosomes.
Biotechnology progress
Cho SH,Contreras LM,Ju SH
R930-25 was used in western blot to study the increase in translational yields by recruiting mRNA for translation as measured by profiling active ribosomes by synthetic chimeras with orthogonal ribosomal proteins
Tue Mar 01 00:00:00 EST 2016
Intranasal immunization with influenza antigens conjugated with cholera toxin subunit B stimulates broad spectrum immunity against influenza viruses.
Human vaccines & immunotherapeutics
Li J,Arévalo MT,Chen Y,Posadas O,Smith JA,Zeng M
R930-25 was used in western blot to study optimization of a universal flu vaccine.
Mon Jun 22 00:00:00 EDT 2015
Transport by populations of fast and slow kinesins uncovers novel family-dependent motor characteristics important for in vivo function.
Biophysical journal
Arpağ G,Shastry S,Hancock WO,Tüzel E
R930-25 was used in a microtubule gliding assay to study how diverse kinesins attached to the same cargo coordinate their movement.
Tue Oct 21 00:00:00 EDT 2014
Exploring nuclear pore complex molecular architecture by immuno-electron microscopy using Xenopus oocytes.
Methods in cell biology
Panté N,Fahrenkrog B
R930-25 was used in immunocytochemistry to describe methods to examine nuclear pore complexes using Xenopus oocytes.
Thu Apr 16 00:00:00 EDT 2015
Fibrillin-1 directly regulates osteoclast formation and function by a dual mechanism.
Journal of cell science
Tiedemann K,Boraschi-Diaz I,Rajakumar I,Kaur J,Roughley P,Reinhardt DP,Komarova SV
R930-25 was used in Western Blotting to highlight a direct dual inhibitory role of N-terminal fibrillin-1 fragments in osteoclastogenesis, the sequestration of RANKL and the inhibition of NFATc1 signaling.
Sun Sep 15 00:00:00 EDT 2013
Fibulin-3, -4, and -5 are highly susceptible to proteolysis, interact with cells and heparin, and form multimers.
The Journal of biological chemistry
Djokic J,Fagotto-Kaufmann C,Bartels R,Nelea V,Reinhardt DP
Published figure using 6x-His Tag monoclonal antibody (Product # R930-25) in Western Blot
Fri Aug 02 00:00:00 EDT 2013
The effector and scaffolding proteins AF6 and MUPP1 interact with connexin36 and localize at gap junctions that form electrical synapses in rodent brain.
The European journal of neuroscience
Li X,Lynn BD,Nagy JI
R930-25 was used in western blot to investigate the roles of gap junctions in neuronal circuitry.
Sun Jan 01 00:00:00 EST 2012
Molecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site.
Proceedings of the National Academy of Sciences of the United States of America
Limbach C,Laue MM,Wang X,Hu B,Thiede N,Hultqvist G,Kilimann MW
R930-25 was used in Western Blotting to determine the spatial organisation of Aczonin/Piccolo in situ.
Tue Aug 02 00:00:00 EDT 2011
Characterization of the 41kDa allergen Asp v 13, a subtilisin-like serine protease from Aspergillus versicolor.
Molecular immunology
Shi C,Miller JD
R930-25 was used in western blot to identify epitopes of Asp v 13.
Thu Sep 01 00:00:00 EDT 2011
High-throughput subcellular protein localization using transfected-cell arrays. Subcellular protein localization using cell arrays.
Methods in molecular biology (Clifton, N.J.)
Hu Y,Janitz M
R930-25 was used in In vitro experiments to facilitate the precise determination of the localizations of numerous recombinant proteins in a single experiment, making it currently the most efficient technique for high-throughput protein co-localization screening.
Tue Mar 22 00:00:00 EDT 2011
Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other.
The Journal of biological chemistry
Ambrosi C,Gassmann O,Pranskevich JN,Boassa D,Smock A,Wang J,Dahl G,Steinem C,Sosinsky GE
R930-25 was used in western blot to investigate Pannexin1 or Pannexin2 complexes
Fri Aug 06 00:00:00 EDT 2010
Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other.
The Journal of biological chemistry
Ambrosi C,Gassmann O,Pranskevich JN,Boassa D,Smock A,Wang J,Dahl G,Steinem C,Sosinsky GE
R930-25 was used in western blot to investigate Pannexin1 or Pannexin2 complexes
Fri Aug 06 00:00:00 EDT 2010
A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Wang X,Hu B,Zieba A,Neumann NG,Kasper-Sonnenberg M,Honsbein A,Hultqvist G,Conze T,Witt W,Limbach C,Geitmann M,Danielson H,Kolarow R,Niemann G,Lessmann V,Kilimann MW
R930-25 was used in Western Blotting to find that domains of five active zone proteins converge on an interaction node centred on the N-terminal region of Munc13-1.
Wed Oct 07 00:00:00 EDT 2009
Translation of ASH1 mRNA is repressed by Puf6p-Fun12p/eIF5B interaction and released by CK2 phosphorylation.
Genes & development
Deng Y,Singer RH,Gu W
Published figure using 6x-His Tag monoclonal antibody (Product # R930-25) in Western Blot
Tue Apr 15 00:00:00 EDT 2008
RIP1 links inflammatory and growth factor signaling pathways by regulating expression of the EGFR.
Cell death and differentiation
Ramnarain DB,Paulmurugan R,Park S,Mickey BE,Asaithamby A,Saha D,Kelliher MA,Mukhopadhyay P,Banani F,Madden CJ,Wright PS,Chakravarty S,Habib AA
R930-25 was used in Western Blotting to identify a link between inflammatory and growth factor signalling pathways mediated by receptor-interacting protein (RIP1), providing insight into the mechanism used by RIP1 to regulate epidermal growth factor receptor levels.
Fri Feb 01 00:00:00 EST 2008
Ecto-F1-ATPase and MHC-class I close association on cell membranes.
Molecular immunology
Vantourout P,Martinez LO,Fabre A,Collet X,Champagne E
R930-25 was used in Immunocytochemistry-immunoflourescence to study the close association between Ecto-F1-ATPase and MHC-class I antigens on cell membranes.
Tue Jan 01 00:00:00 EST 2008
Porcine SPDYA2 (RINGO A2) stimulates CDC2 activity and accelerates meiotic maturation of porcine oocytes.
Biology of reproduction
Kume S,Endo T,Nishimura Y,Kano K,Naito K
R930-25 was used in Western Blotting to study the role SPDY proteins, the mammalian homologues of the RINGO family, on meiotic maturation of mammalian oocytes.
Thu Mar 01 00:00:00 EST 2007
Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance.
Proceedings of the National Academy of Sciences of the United States of America
Sugimoto M,Fujikawa A,Womack JE,Sugimoto Y
R930-25 was used in immunoprecipitation to study the role of FEZL-SEMA5A pathway in neuronal development and innate immunity in cows
Tue Apr 25 00:00:00 EDT 2006
A novel mitochondrial protein DIP mediates E2F1-induced apoptosis independently of p53.
Cell death and differentiation
Stanelle J,Tu-Rapp H,Pützer BM
R930-25 was used in Immunocytochemistry-immunoflourescence to investigate the biological function of the interaction between Death-Inducing-Protein and E2F1.
Fri Apr 01 00:00:00 EST 2005
Identification of TINO: a new evolutionarily conserved BCL-2 AU-rich element RNA-binding protein.
The Journal of biological chemistry
Donnini M,Lapucci A,Papucci L,Witort E,Jacquier A,Brewer G,Nicolin A,Capaccioli S,Schiavone N
R930-25 was used in Western Blotting to identify a novel human protein that interacts with BCL-2 AU-rich elements.
Fri May 07 00:00:00 EDT 2004
Fibroblast growth factor-10 is a mitogen for urothelial cells.
The Journal of biological chemistry
Bagai S,Rubio E,Cheng JF,Sweet R,Thomas R,Fuchs E,Grady R,Mitchell M,Bassuk JA
Published figure using 6x-His Tag monoclonal antibody (Product # R930-25) in Western Blot
Fri Jun 28 00:00:00 EDT 2002
A novel leucine zipper targets AKAP15 and cyclic AMP-dependent protein kinase to the C terminus of the skeletal muscle Ca2+ channel and modulates its function.
The Journal of biological chemistry
Hulme JT,Ahn M,Hauschka SD,Scheuer T,Catterall WA
R930-25 was used in western blot to investigate the mechanism by which AKAP15 targets PKA to L-type Ca(2+) channels
Fri Feb 08 00:00:00 EST 2002
A proteolytic transmembrane signaling pathway and resistance to beta-lactams in staphylococci.
Science (New York, N.Y.)
Zhang HZ,Hackbarth CJ,Chansky KM,Chambers HF
R930-25 was used in western blot to study the regulation of beta-lactamase and penicillin-binding protein 2a
Fri Mar 09 00:00:00 EST 2001
An unsuspected autoregulatory pathway involving apocytochrome TorC and sensor TorS in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America
Gon S,Jourlin-Castelli C,Théraulaz L,Méjean V
R930-25 was used in western blot to study regulation of TorC in E. coli
Tue Sep 25 00:00:00 EDT 2001
