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RAB17 Polyclonal Antibody

RAB17 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 3

RAB17 Antibody (17501-1-AP) in ICC/IF

IF result of RAB17 antibody (17501-1-AP) with WIF-B cells overexpressed myc-tagged RAB17 by A.C. Striz and Dr. P.L. Tuma.

RAB17 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

17501-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:25-1:50

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

RAB17 Fusion Protein Ag11688 (1-212 aa encoded by BC050426)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.35 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAQAHRTPQ PRAAPSQPRV FKLVLLGSGS VGKSSLALRY VKNDFKSILP TVGCAFFTKV VDVGATSLKL EIWDTAGQEK YHSVCHLYFR GANAALLVYD ITRKDSFLKA QQWLKDLEEE LHPGEVLVML VGNKTDLSQE REVTFQEGKE FADSQKLLFM ETSAKLNHQV SEVFNTVAQE LLQRSDEEGQ ALRGDAAVAL NKGPARQAKC CAH (1-212 aa encoded by BC050426)

Target Information

The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Downregulation of RAB17 have a poor prognosis in kidney renal clear cell carcinoma and its expression correlates with DNA methylation and immune infiltration.

Cellular signalling

Zeng Z,Zhang Z,Cheng X,Yang H,Gong B,Zhou X,Zhang C,Wang X,Wang G

Fri Sep 01 00:00:00 EDT 2023

The Role of RAB GTPases and Its Potential in Predicting Immunotherapy Response and Prognosis in Colorectal Cancer.

Frontiers in genetics

Jiang X,Yang L,Gao Q,Liu Y,Feng X,Ye S,Yang Z

Wed Feb 16 00:00:00 EST 2022

The Role of RAB GTPases and Its Potential in Predicting Immunotherapy Response and Prognosis in Colorectal Cancer.

Frontiers in genetics

Jiang X,Yang L,Gao Q,Liu Y,Feng X,Ye S,Yang Z

Wed Feb 16 00:00:00 EST 2022

Intercellular transfer of exosomal wild type EGFR triggers osimertinib resistance in non-small cell lung cancer.

Molecular cancer

Wu S,Luo M,To KKW,Zhang J,Su C,Zhang H,An S,Wang F,Chen D,Fu L

Mon Jan 18 00:00:00 EST 2021

Intercellular transfer of exosomal wild type EGFR triggers osimertinib resistance in non-small cell lung cancer.

Molecular cancer

Wu S,Luo M,To KKW,Zhang J,Su C,Zhang H,An S,Wang F,Chen D,Fu L

Mon Jan 18 00:00:00 EST 2021

Rab17 regulates apical delivery of hepatic transcytotic vesicles.

Molecular biology of the cell

Striz AC,Stephan AP,López-Coral A,Tuma PL

Thu Nov 15 00:00:00 EST 2018

The GTP-bound and Sumoylated Form of the rab17 Small Molecular Weight GTPase Selectively Binds Syntaxin 2 in Polarized Hepatic WIF-B Cells.

The Journal of biological chemistry

Striz AC,Tuma PL

Fri Apr 29 00:00:00 EDT 2016

Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis.

Cell death & disease

Yin C,Kim Y,Argintaru D,Heit B

Thu Dec 22 00:00:00 EST 2016

Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis.

Cell death & disease

Yin C,Kim Y,Argintaru D,Heit B

Thu Dec 22 00:00:00 EST 2016

Bioinformatics

Protein Aliases: Ras-related protein Rab-17

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Gene Aliases: RAB17

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UniProt ID: (Human) Q9H0T7

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Entrez Gene ID: (Human) 64284

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Function(s)

GTPase activity protein binding GTP binding GDP binding

Process(es)

immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor small GTPase mediated signal transduction protein transport regulation of endocytosis establishment of melanosome localization melanosome transport endocytic recycling cilium assembly transcytosis filopodium assembly regulation of dendrite development regulation of filopodium assembly regulation of synapse assembly

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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RAB17 Polyclonal Antibody

RAB17 Antibody (17501-1-AP) in ICC/IF

Product Details

17501-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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