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Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rabs are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking. The mammalian RAB proteins show striking similarities to the S. cerevisiae YPT1 and SEC4 proteins, Ras-related GTP-binding proteins involved in the regulation of secretion.
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Protein Aliases: GTP-binding protein; GTP-binding protein RAB2B; rab 2; RAB2, member RAS oncogene family; RAS family, member RAB2B; Ras-related protein Rab-2A; Ras-related protein Rab-2B; small GTP binding protein RAB2A
Gene Aliases: 1500012D09Rik; 4930528G15Rik; 9330148M11Rik; A230002G14; C80220; D530043M21Rik; LHX; RAB2; RAB2A; RAB2B
UniProt ID: (Human) P61019, (Human) Q8WUD1, (Mouse) P53994, (Rat) P05712, (Mouse) P59279
Entrez Gene ID: (Human) 5862, (Human) 84932, (Mouse) 59021, (Rat) 65158, (Rat) 305853, (Mouse) 76338
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