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RAB8B Antibody (PA5-45012) in WB
Western blot analysis of human, mouse cell lysate using an anti-RAB8B polyclonal antibody (Product # PA5-45012).; Secondary Antibody: goat anti-Rabbit LANE 1)Human Cervical Cancer Cell Lysate (15µg); LANE 2) Monkey Fibroblast Cell Lysate (15µg); LANE 3) Human Cervical Cancer Cell transfected with mouse Rab8B-GFP (15µg).
Product Details
PA5-45012
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the C-terminal of human RAB8B
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2606233
Product Specific Information
Peptide sequence: RNIEEHASSD VERMILGNKC DMNDKRQVSK ERGEKLAIDY GIKFLETSAK
Sequence homology: Cow: 100%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%; Zebrafish: 100%
Target Information
The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab superfamilies exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. Rab 8B (Ras-related protein Rab-8B) is a 207 amino acid lipid anchor that localizes to the cytoplasmic side of the cell membrane and belongs to the Rab family and small GTPase superfamily. Rab 8B may be involved in neurotransmitter release and vesicular trafficking, and is encoded by a gene located on human chromosome Rab 8B and mouse chromosome 9 C.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ38125; RAB-8b protein; Ras-related protein Rab-8B
Gene Aliases: RAB8B
UniProt ID: (Human) Q9P293
Entrez Gene ID: (Human) 51762
vesicle docking involved in exocytosis
small GTPase mediated signal transduction
protein secretion
antigen processing and presentation
positive regulation of cell projection organization
adherens junction organization
cilium assembly
protein import into peroxisome membrane
positive regulation of corticotropin secretion
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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