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Invitrogen
RAC1/RAC2/RAC3 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Product Details
PA5-61600
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RAC1/RAC2/RAC3
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2646272
Product Specific Information
Immunogen sequence: TKLDLRDDKD TIERLRDKKL APITYPQGLA MAREI
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell migration-inducing gene 5 protein; GX; p21-Rac1; p21-Rac2; p21-Rac3; Ras-like protein TC25; Ras-related C3 botulinum toxin substrate 1; Ras-related C3 botulinum toxin substrate 2; Ras-related C3 botulinum toxin substrate 3; Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2); rho family, small GTP binding protein Rac3; Small G protein
Gene Aliases: EN-7; Gx; HSPC022; MIG5; p21-Rac1; p21-Rac2; Rac-1; RAC1; RAC2; RAC3; TC-25; TC25
UniProt ID: (Human) P63000, (Human) P15153, (Human) P60763
Entrez Gene ID: (Human) 5879, (Human) 5880, (Human) 5881
positive regulation of protein phosphorylation
auditory receptor cell morphogenesis
mast cell chemotaxis
epithelial cell morphogenesis
movement of cell or subcellular component
inflammatory response
hyperosmotic response
cell adhesion
cell-matrix adhesion
G-protein coupled receptor signaling pathway
small GTPase mediated signal transduction
axon guidance
blood coagulation
cell proliferation
regulation of cell size
response to wounding
anatomical structure morphogenesis
regulation of hydrogen peroxide metabolic process
positive regulation of lamellipodium assembly
regulation of fibroblast migration
positive regulation of cell-substrate adhesion
regulation of neuron maturation
cerebral cortex radially oriented cell migration
embryonic olfactory bulb interneuron precursor migration
cerebral cortex GABAergic interneuron development
lamellipodium assembly
actin cytoskeleton organization
actin filament polymerization
platelet activation
regulation of cell migration
positive regulation of actin filament polymerization
T cell costimulation
ruffle organization
negative regulation of interleukin-23 production
substrate adhesion-dependent cell spreading
positive regulation of Rho protein signal transduction
intracellular signal transduction
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of apoptotic process
positive regulation of phosphatidylinositol 3-kinase activity
engulfment of apoptotic cell
cell-cell junction organization
bone resorption
positive regulation of DNA replication
vascular endothelial growth factor receptor signaling pathway
ephrin receptor signaling pathway
negative regulation of receptor-mediated endocytosis
anatomical structure arrangement
dendrite morphogenesis
cell motility
homeostasis of number of cells within a tissue
regulation of defense response to virus by virus
regulation of small GTPase mediated signal transduction
positive regulation of stress fiber assembly
localization within membrane
positive regulation of focal adhesion assembly
synaptic transmission, GABAergic
Wnt signaling pathway, planar cell polarity pathway
regulation of respiratory burst
cellular response to mechanical stimulus
semaphorin-plexin signaling pathway
dopaminergic neuron differentiation
protein localization to plasma membrane
positive regulation of neutrophil chemotaxis
cochlea morphogenesis
ruffle assembly
positive regulation of substrate adhesion-dependent cell spreading
chemotaxis
actin filament organization
signal transduction
positive regulation of cell proliferation
regulation of cell-substrate adhesion
cell projection assembly
regulation of T cell proliferation
regulation of mast cell degranulation
regulation of protein kinase activity
regulation of mast cell chemotaxis
lymphocyte aggregation
regulation of neutrophil migration
positive regulation of protein targeting to mitochondrion
neuron projection development
positive regulation of cell adhesion mediated by integrin
neuromuscular process controlling balance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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