Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MRRISLTSSP VRLLLFLLLL LIALEIMVGG HSLCFNFTIK SLSRPGQPWC EAQVFLNKNL FLQYNSDNNM VKPLGLLGKK VNATSTWGEL TQTLGEVGRD LRMLLCDIKP QIKTSDPSTL QVEMFCQHEA ERCTGASWQF TINGEKSLLF DAMNMTWTVI NHEASKIKET WKKDRGLEKY FRKLSKGDCD HWLREFLGHW EAMPEPTVSP VNASDIHWSS SSLPDRWIIL GAFILLLLMG IVLICVWWQN GEWQAGLWPL RTS
This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Lymphocyte effector toxicity activation ligand; MGC125309; N2DL-4; NKG2D ligand 4; RAE-1-like transcript 4; RAE1 like transcript 4; Retinoic acid early transcript 1E; UL16 binding protein 4; UL16-binding protein 4; ULBP 4; ULBP4MGC125308
Gene Aliases: bA350J20.7; LETAL; N2DL-4; N2DL4; NKG2DL4; RAET1E; RAET1E2; RL-4; ULBP4; UNQ1867/PRO4303
UniProt ID: (Human) Q8TD07
Entrez Gene ID: (Human) 135250
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