Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MTECFLPPT SSPSEHRRVE HGSGLTRTPS SEEISPTKFP GLYRTGEPSP PHDILHEPPD VVSDDEKDHG KKKGKFKKKE KRTEGYAAFQ EDSSGDEAES PSKMKRSKGI HVFKKPSFSK KKEKDFKIKE KPKEEKHKEE KHKEEKHKEK KSKDLTAADV VKQWKEKKKK KKPIQEPEVP QIDVPNLKPI FGIPLADAVE RTMMYDGIRL PAVFRECIDY VEKYGMKCEG IYRVSGIKSK VDELKAAYDR EESTNLEDYE PNTVASLLKQ YLRDLPENLL TKELMPRFEE ACGRTTETEK VQEFQRLLKE LPECNYLLIS WLIVHMDHVI AKELETKMNI QNISIVLSPT VQ (1-351 aa encoded by BC013126)
Can specifically activate hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 76 kDa Ral-interacting protein; Dinitrophenyl S-glutathione ATPase; DNP-SG ATPase; Ral-interacting protein 1; RalA-binding protein 1; RalBP1; RIP
Gene Aliases: RALBP1; RIP1; RLIP; RLIP1; RLIP76
UniProt ID: (Human) Q15311
Entrez Gene ID: (Human) 10928
Molecular Function:
G-protein modulator
protein-binding activity modulator
GTPase-activating protein
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support