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RALBP1 Antibody (PA5-88123) in WB
Western blot analysis of RALBP1 in extracts of various cell lines. Samples were incubated with RALBP1 Polyclonal antibody (Product # PA5-88123) using a dilution of 1:500, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Product Details
PA5-88123
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 396-655 of human RALBP1 (NP_0067791)
Conjugate
Form
Liquid
Concentration
8.73 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804670
Product Specific Information
Immunogen sequence: AGIKEEIRRQ EFLLNCLHRD LQGGIKDLSK EERLWEVQRI LTALKRKLRE AKRQECETKI AQEIASLSKE DVSKEEMNEN EEVINILLAQ ENEILTEQEE LLAMEQFLRR QIASEKEEIE RLRAEIAEIQ SRQQHGRSET EEYSSESESE SEDEEELQII LEDLQRQNEE LEIKNNHLNQ AIHEEREAII ELRVQLRLLQ MQRAKAEQQA QEDEEPEWRG GAVQPPRDGV LEPKAAKEQP KAGKEPAKPS PSRDRKETSI; Positive Samples: A-673, Mouse spleen, Mouse lung; Cellular Location: Membrane, Peripheral membrane protein
Target Information
Can specifically activate hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dinitrophenyl S-glutathione ATPase; DNP-SG ATPase; Ral-interacting protein 1; RalA-binding protein 1; RalBP1; RIP
Gene Aliases: Ralbp1; Rip1; RLIP76
UniProt ID: (Mouse) Q62172
Entrez Gene ID: (Mouse) 19765
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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