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Immunogen sequence: LRFLCPAIM SPSLFNLMQE YPDDRTSRTL TLIAKVIQNL ANFAKFGNKE EYMAFMNDFL EHEWGGMKRF LLEISNPDTI SNTPGFDGYI DLGRELSVLH SLLWEVVSQL DKATVAKLGP LPRVLADITK SLTNPTPIQQ QLRRFTEHNS SPNVSGSLSS GLQKIFEDPT DSDLHKLKSP SQDNTDSYFR GKTLLLVQQA SSQSMTYSEK DERESSLPNG RSVSLMDLQD THAAQVEHAS VMLDVPIRLT GSQLSITQVA SIKQLRETQS TPQSAPQVRR PLHPALNQPG GLQPLSFQNP VYHLNNPIPA MPKASIDSSL ENLSTASSRS QSNSEDFKLS GPSNSSMEDF T (609-958 aa encoded by BC110611)
This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ras GTPase-activating protein nGAP; Ras protein activator like 1; RAS protein activator-like 2
Gene Aliases: NGAP; RASAL2
UniProt ID: (Human) Q9UJF2
Entrez Gene ID: (Human) 9462
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