Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MTVDSSMSSG YCSLDEELED CFFTAKTTFF RNAQSKHLSK NVCKPVEETQ RPPTLQEIKQ KIDSYNTREK NCLGMKLSED GTYTGFIKVH LKLRRPVTVP AGIRPQSIYD AIKEVNLAAT TDKRTSFYLP LDAIKQLHIS STTTVSEVIQ GLLKKFMVVD NPQKFALFKR IHKDGQVLFQ KLSIADRPLY LRLLAGPDTE VLSFVLKENE TGEVEWDAFS IPELQNFLTI LEKEEQDKIQ QVQKKYDKFR QKLEEALRES QGKPG
This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC10823; MGC17344; New ras effector 1; novel Ras effector 1; Rap1-binding protein; RAPL; Ras association (RalGDS/AF-6) domain family 5; Ras association (RalGDS/AF-6) domain family member 5; Ras association domain-containing protein 5; Ras effector-like protein; regulator for cell adhesion and polarization enriched in lymphoid tissue; Regulator for cell adhesion and polarization enriched in lymphoid tissues; RP11-343H5.1; tumor; tumor suppressor RASSF3
Gene Aliases: Maxp1; NORE1; NORE1A; NORE1B; RAPL; RASSF3; RASSF5
UniProt ID: (Human) Q8WWW0
Entrez Gene ID: (Human) 83593
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