Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This antibody is a rabbit polyclonal antibody raised against residues near the N terminus of human RB1CC1.
Immunogen sequence: MKLYVFLVN TGTTLTFDTE LTVQTVADLK HAIQSKYKIA IQHQVLVVNG GECMAADRRV CTYSAGTDTN PIFLFNKEMI LCDRPPAIPK TTFSTENDME IKVEESLMMP AVFHTVASRT QLALEMYEVA KKLCSFCEGL VHDEHLQHQG WAAIMANLED CSNSYQKLLF KFESIYSNYL QSIEDIKLKL THLGTAVSVM AKIPLLECLT RHSYRECLGR LDSLPEHEDS EKAETKRSTE LVLSPDMPRT TNESLLTSFP KSVEHVSPDT ADAESGKEIR ESCQSTVHQQ DETTIDTKDG DLPFFNVSLL DWINVQDRPN DVESLVRKCF DSMSRLDPRI IRPFIAECRQ T (1-350 aa encoded by BC017556)
The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 200 kDa FAK family kinase-interacting protein; coiled coil forming protein 1; Coiled-coil-forming protein 1; FAK family kinase-interacting protein of 200 kDa; FIP200; LaXp180; phosphatase 1, regulatory subunit 131; RB1-inducible coiled-coil 1; RB1-inducible coiled-coil protein 1
Gene Aliases: 2900055E04Rik; 5930404L04Rik; ATG17; CC1; FIP200; KIAA0203; LaXp180; PPP1R131; RB1CC1; RBICC
UniProt ID: (Human) Q8TDY2, (Mouse) Q9ESK9
Entrez Gene ID: (Human) 9821, (Mouse) 12421, (Rat) 312927
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