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RBBP9 may play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1.The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate.
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Protein Aliases: B5T overexpressed gene protein; B5T-overexpressed gene protein; MGC9236; Protein BOG; RBBP-10; RBBP-9; retinoblastoma binding protein 9; Retinoblastoma-binding protein 10; Retinoblastoma-binding protein 9; retinoma-binding protein 9; Serine hydrolase RBBP9
Gene Aliases: BOG; RBBP10; RBBP9
UniProt ID: (Human) O75884
Entrez Gene ID: (Human) 10741
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