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Product Details
PA5-68875
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide corresponding to a region of mouse RBFOX2
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2688737
Product Specific Information
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
Target Information
This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fox-1 homolog B; Fox-1 homolog Fxh; Fyn-binding molecule 2; Hexaribonucleotide-binding protein 2; RNA binding protein fox-1 homolog 2; RNA-binding motif protein 9; RNA-binding protein 9
Gene Aliases: Fbm2; Fox2; Fxh; Hrnbp2; Rbfox2; Rbm9
UniProt ID: (Mouse) Q8BP71
Entrez Gene ID: (Mouse) 93686
regulation of alternative mRNA splicing, via spliceosome
mRNA processing
RNA splicing
regulation of definitive erythrocyte differentiation
radial glia guided migration of Purkinje cell
intracellular estrogen receptor signaling pathway
regulation of RNA splicing
negative regulation of transcription, DNA-templated
dendrite morphogenesis
neuromuscular process controlling balance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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