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Product Details
MA5-42896
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
8O0V8
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 102-201 of human RBP4 (P02753).
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2912037
Product Specific Information
Positive test controls include: HepG2.
Immunogen sequence: AKFKMKYWGV ASFLQKGNDD HWIVDTDYDT YAVQYSCRLL NLDGTCADSY SFVFSRDPNG LPPEAQKIVR QRQEELCLAR QYRLIVHNGY CDGRSERNLL
Target Information
This protein belongs to the lipocalin family and is the specific carrier for retinol in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post translationally and results in defective delivery and supply to the epidermal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Plasma retinol binding protein 4 (PRBP); Plasma retinol-binding protein; PRBP; RBP; retinol; retinol binding; Retinol binding protein 4 interstitial; retinol binding protein 4, cellular; retinol binding protein 4, plasma; Retinol-binding protein 4; retinol-binding protein 4, interstitial
Gene Aliases: MCOPCB10; PRO2222; Rbp-4; RBP4; RBPA; RDCCAS
UniProt ID: (Human) P02753, (Rat) P04916, (Mouse) Q00724
Entrez Gene ID: (Human) 5950, (Rat) 25703, (Mouse) 19662
retinoid metabolic process
eye development
gluconeogenesis
heart development
visual perception
maintenance of gastrointestinal epithelium
lung development
positive regulation of insulin secretion
response to retinoic acid
retinol transport
retinol metabolic process
glucose homeostasis
response to ethanol
embryonic organ morphogenesis
embryonic skeletal system development
cardiac muscle tissue development
female genitalia morphogenesis
positive regulation of immunoglobulin secretion
negative regulation of cardiac muscle cell proliferation
embryonic retina morphogenesis in camera-type eye
uterus development
vagina development
urinary bladder development
heart trabecula formation
transport
spermatogenesis
male gonad development
response to insulin
retinal metabolic process
detection of light stimulus involved in visual perception
vitamin transport
retina development in camera-type eye
embryo development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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