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Product Details
H00005962-M03
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
1F6
Immunogen
RDX (AAH47109, 1 a.a. approximately 583 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MPKPINVRVT TMDAELEFAI QPNTTGKQLF DQVVKTVGLR EVWFFGLQYV DSKGYSTWLK LNKKVTQQDV KKENPLQFKF RAKFFPEDVS EELIQEITQR LFFLQVKEAI LNDEIYCPPE TAVLLASYAV QAKYGDYNKE IHKPGYLAND RLLPQRVLEQ HKLTKEQWEE RIQNWHEEHR GMLREDSMME YLKIAQDLEM YGVNYFEIKN KKGTELWLGV DALGLNIYEH DDKLTPKIGF PWSEIRNISF NDKKFVIKPI DKKAPDFVFY APRLRINKRI LALCMGNHEL YMRRRKPDTI EVQQMKAQAR EEKHQKQLER AQLENEKEKR EIAEKEKERI EREKEELMER LKQIEEQTIK AQKELEEQTR KALELDQERK RAKEEAERLE KERRAAEEAK SAIAKQAADQ MKNQEQLAAE LAEFTAKIAL LEEAKKKKEE EATEWQHKAF AAQEDLEKTK EELKTVMSAP PPPPPPPVIP PTENEHDEHD ENNAEASAEL SNEGVMNHRS EEERVTETQK NERVKKQLQA LSSELAQARD ETKKTQNDVL HAENVKAGRD KYKTLRQIRQ GNTKQRIDEF EAM
Target Information
Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Radixin
Gene Aliases: DFNB24; RDX
UniProt ID: (Human) P35241
Entrez Gene ID: (Human) 5962
regulation of cell shape
regulation of cell size
positive regulation of gene expression
protein kinase A signaling
microvillus assembly
positive regulation of cell migration
regulation of actin filament bundle assembly
regulation of Rap protein signal transduction
negative regulation of homotypic cell-cell adhesion
negative regulation of GTPase activity
regulation of GTPase activity
apical protein localization
establishment of protein localization
negative regulation of cell size
actin filament capping
establishment of endothelial barrier
establishment of protein localization to plasma membrane
cellular response to thyroid hormone stimulus
cell-cell adhesion
regulation of ruffle assembly
positive regulation of G1/S transition of mitotic cell cycle
regulation of organelle assembly
positive regulation of protein localization to early endosome
positive regulation of cellular protein catabolic process
negative regulation of adherens junction organization
positive regulation of early endosome to late endosome transport
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