Product References
Viral vector gene delivery of the novel chaperone protein SRCP1 to modify insoluble protein in in vitro and in vivo models of ALS.
Gene therapy
Luecke IW,Lin G,Santarriaga S,Scaglione KM,Ebert AD
MA5-15257 was used in Immunohistochemistry to indicate that SRCP1 likely reduces insoluble protein burden in a protein and/or context-dependent manner indicating a need for additional insight into SRCP1 function and therapeutic potential.
Thu Jun 01 00:00:00 EDT 2023
Viral vector gene delivery of the novel chaperone protein SRCP1 to modify insoluble protein in in vitro and in vivo models of ALS.
Gene therapy
Luecke IW,Lin G,Santarriaga S,Scaglione KM,Ebert AD
MA5-15257 was used in Immunohistochemistry to indicate that SRCP1 likely reduces insoluble protein burden in a protein and/or context-dependent manner indicating a need for additional insight into SRCP1 function and therapeutic potential.
Thu Jun 01 00:00:00 EDT 2023
Hyperphosphorylated PTEN exerts oncogenic properties.
Nature communications
van Ree JH,Jeganathan KB,Fierro Velasco RO,Zhang C,Can I,Hamada M,Li H,Baker DJ,van Deursen JM
MA5-15257 was used in Western Blotting to suggest that C-tail hyperphosphorylation creates oncogenic PTEN and is a potential target for anti-cancer therapy.
Wed May 24 00:00:00 EDT 2023
Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer.
Nature cancer
Perelli L,Carbone F,Zhang L,Huang JK,Le C,Khan H,Citron F,Del Poggetto E,Gutschner T,Tomihara H,Soeung M,Minelli R,Srinivasan S,Peoples M,Lam TNA,Lundgren S,Xia R,Zhu C,Mohamed AMT,Zhang J,Sircar K,Sgambato A,Gao J,Jonasch E,Draetta GF,Futreal A,Bakouny Z,Van Allen EM,Choueiri T,Signoretti S,Msaouel P,Litchfield K,Turajlic S,Wang L,Chen YB,Di Natale RG,Hakimi AA,Giuliani V,Heffernan TP,Viale A,Bristow CA,Tannir NM,Carugo A,Genovese G
MA5-15257 was used in Immunohistochemistry to provide critical knowledge on drivers of renal cell carcinoma progression and defines the primary role of interferon signaling in constraining the propagation of aneuploid clones in cancer evolution.
Sat Jul 01 00:00:00 EDT 2023
Chronic Alcohol Drinking Drives Sex-Specific Differences in Affective Behavior and Medial Prefrontal Cortex Activity in CRF1:Cre:tdTomato Transgenic Rats.
eNeuro
Quadir SG,Arleth GM,Cone MG,High MW,Ramage MC,Effinger DP,Echeveste Sanchez M,Herman MA
MA5-15257 was used in Immunohistochemistry to suggest complex interplay between affective state, alcohol drinking, and the role of prefrontal CRF1+ neurons in mediating these behaviors.
Sat Jul 01 00:00:00 EDT 2023
Gli1 Regulates the Postnatal Acquisition of Peripheral Nerve Architecture.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Zotter B,Dagan O,Brady J,Baloui H,Samanta J,Salzer JL
MA5-15257 was used in Immunohistochemistry-immunofluorescence to delineate how peripheral nerves acquire their distinctive organization during normal development, and highlight mechanisms that may regulate their reorganization in pathologic settings, including peripheral neuropathies and nerve injury.
Wed Jan 12 00:00:00 EST 2022
DDX60 selectively reduces translation off viral type II internal ribosome entry sites.
EMBO reports
Sadic M,Schneider WM,Katsara O,Medina GN,Fisher A,Mogulothu A,Yu Y,Gu M,de Los Santos T,Schneider RJ,Dittmann M
Published figure using RFP monoclonal antibody (Product # MA5-15257) in Western Blot
Tue Dec 06 00:00:00 EST 2022
AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway.
Molecular therapy : the journal of the American Society of Gene Therapy
Liang SQ,Walkey CJ,Martinez AE,Su Q,Dickinson ME,Wang D,Lagor WR,Heaney JD,Gao G,Xue W
MA5-15257 was used in Immunohistochemistry-immunofluorescence to show that this highly effective AAV delivery platform will facilitate the study of therapeutic genome editing in the lung and other tissue types.
Wed Jan 05 00:00:00 EST 2022
Platinum Chemotherapy Induces Lymphangiogenesis in Cancerous and Healthy Tissues That Can be Prevented With Adjuvant Anti-VEGFR3 Therapy.
Frontiers in oncology
Harris AR,Esparza S,Azimi MS,Cornelison R,Azar FN,Llaneza DC,Belanger M,Mathew A,Tkachenko S,Perez MJ,Rosean CB,Bostic RR,Cornelison RC,Tate KM,Peirce-Cottler SM,Paquette C,Mills A,Landen CN,Saucerman J,Dillon PM,Pompano RR,Rutkowski MA,Munson JM
MA5-15257 was used in Immunohistochemistry to show that carboplatin treatment of healthy mice prior to mammary tumor inoculation increased cancer metastasis as compared to no pre-treatment and that these platinum-induced phenomena could be blocked by VEGFR3 inhibition.
Mon Nov 21 00:00:00 EST 2022
Critical role for isoprenoids in apicoplast biogenesis by malaria parasites.
eLife
Okada M,Rajaram K,Swift RP,Mixon A,Maschek JA,Prigge ST,Sigala PA
MA5-15257 was used in Western Blot to hypothesize that PPS synthesizes long-chain polyprenols critical for apicoplast membrane fluidity and biogenesis.
Tue Mar 08 00:00:00 EST 2022
Dormant Nfatc1 reporter-marked basal stem/progenitor cells contribute to mammary lobuloalveoli formation.
iScience
Liu R,Hu H,McNeil M,Xu J,Bi X,Lou P,Guerrero-Juarez CF,Dai X,Plikus MV,Shuai J,Yu Z,Lv C
MA5-15257 was used in Immunohistochemistry-immunofluorescence to show that Nfatc1 expression marks a rare population of mammary epithelial cells with the majority being basal epithelial cells.
Fri Mar 18 00:00:00 EDT 2022
Dentate gyrus morphogenesis is regulated by β-catenin function in hem-derived fimbrial glia.
Development (Cambridge, England)
Parichha A,Datta D,Suresh V,Chatterjee M,Holtzman MJ,Tole S
MA5-15257 was used in Immunohistochemistry-immunofluorescence to highlight a primary requirement for β-catenin for the organization of the fimbrial scaffold and a secondary role for this factor in dentate gyrus morphogenesis.
Tue Nov 01 00:00:00 EDT 2022
Optimized protocol for translatome analysis of mouse brain endothelial cells.
PloS one
Kim N,Jun MH,Jeong JY,Oh WJ
MA5-15257 was used in Immunohistochemistry to establish a protocol to isolate highly pure mRNAs from BECs in the cortex of eight- to twelve-week-old male Tie2-Cre; Rpl22HA/HA mice by using a cell strainer to trap blood vessels prior to immunoprecipitation.
Fri Sep 30 00:00:00 EDT 2022
The SARS-unique domain (SUD) of SARS-CoV and SARS-CoV-2 interacts with human Paip1 to enhance viral RNA translation.
The EMBO journal
Lei J,Ma-Lauer Y,Han Y,Thoms M,Buschauer R,Jores J,Thiel V,Beckmann R,Deng W,Leonhardt H,Hilgenfeld R,von Brunn A
Published figure using RFP monoclonal antibody (Product # MA5-15257) in Western Blot
Tue Jun 01 00:00:00 EDT 2021
A fluorescence-based genetic screen reveals diverse mechanisms silencing small RNA signaling in E. coli.
Proceedings of the National Academy of Sciences of the United States of America
Chen J,To L,de Mets F,Luo X,Majdalani N,Tai CH,Gottesman S
MA5-15257 was used in Western Blot to identify regulators that can quench sRNA signaling of the iron-responsive sRNA RyhB in Escherichia coli.
Tue Jul 06 00:00:00 EDT 2021
SynaptoPAC, an optogenetic tool for induction of presynaptic plasticity.
Journal of neurochemistry
Oldani S,Moreno-Velasquez L,Faiss L,Stumpf A,Rosenmund C,Schmitz D,Rost BR
MA5-15257 was used in Immunocytochemistry to establish synaptoPAC as an optogenetic tool that enables acute light-controlled potentiation of transmitter release at specific synapses in the brain, facilitating studies of the role of presynaptic potentiation in network function and animal behavior in an unprecedented manner.
Mon Feb 01 00:00:00 EST 2021
Proteomics of protein trafficking by in vivo tissue-specific labeling.
Nature communications
Droujinine IA,Meyer AS,Wang D,Udeshi ND,Hu Y,Rocco D,McMahon JA,Yang R,Guo J,Mu L,Carey DK,Svinkina T,Zeng R,Branon T,Tabatabai A,Bosch JA,Asara JM,Ting AY,Carr SA,McMahon AP,Perrimon N
MA5-15257 was used in Immunohistochemistry (Frozen) to indicate that the communication network of secreted proteins is vast.
Thu Apr 22 00:00:00 EDT 2021
RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site.
Cell reports
George J,Li Y,Kadamberi IP,Parashar D,Tsaih SW,Gupta P,Geethadevi A,Chen C,Ghosh C,Sun Y,Mittal S,Ramchandran R,Rui H,Lopez-Berestein G,Rodriguez-Aguayo C,Leone G,Rader JS,Sood AK,Dey M,Pradeep S,Chaluvally-Raghavan P
MA5-15257 was used in Immunocytochemistry-immunoflourescence to uncover a mechanism by which FXR1 promotes cMYC levels in cancer cells.
Tue Nov 02 00:00:00 EDT 2021
Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogenesis and Osteogenesis Imperfecta.
Nature communications
Chen Y,Yang S,Lovisa S,Ambrose CG,McAndrews KM,Sugimoto H,Kalluri R
MA5-15257 was used in Immunohistochemistry to demonstrate specific contributions of mesenchymal cell lineages to Col1 production in organogenesis, skeletal development, and bone formation/repair, with potential insights into cell-based therapy for patients with Osteogenesis Imperfecta.
Fri Dec 10 00:00:00 EST 2021
Stem cell spreading dynamics intrinsically differentiate acral melanomas from nevi.
Cell reports
Eshiba S,Namiki T,Mohri Y,Aida T,Serizawa N,Shibata T,Morinaga H,Nanba D,Hiraoka Y,Tanaka K,Miura K,Tanaka M,Uhara H,Yokozeki H,Saida T,Nishimura EK
MA5-15257 was used in Immunohistochemistry to develop fate-tracing technologies of melanocyte stem cells in sweat glands (glandular McSCs) and in melanoma models in mice and compare the cellular dynamics with human melanoma.
Tue Aug 03 00:00:00 EDT 2021
Sensory Neurons Contacting the Cerebrospinal Fluid Require the Reissner Fiber to Detect Spinal Curvature In Vivo.
Current biology : CB
Orts-Del'Immagine A,Cantaut-Belarif Y,Thouvenin O,Roussel J,Baskaran A,Langui D,Koëth F,Bivas P,Lejeune FX,Bardet PL,Wyart C
MA5-15257 was used in Immunohistochemistry-immunofluorescence to uncover that neurons contacting the cerebrospinal fluid functionally interact with the RF to detect spinal curvature in the vertebrate spinal cord.
Mon Mar 09 00:00:00 EDT 2020
Labeling Dual Presynaptic Inputs using cFork Anterograde Tracing System.
Experimental neurobiology
Oh JY,Han JH,Lee H,Han YE,Rah JC,Park H
Published figure using RFP monoclonal antibody (Product # MA5-15257) in Immunohistochemistry
Tue Jun 30 00:00:00 EDT 2020
Labeling Dual Presynaptic Inputs using cFork Anterograde Tracing System.
Experimental neurobiology
Oh JY,Han JH,Lee H,Han YE,Rah JC,Park H
Published figure using RFP monoclonal antibody (Product # MA5-15257) in Immunohistochemistry
Tue Jun 30 00:00:00 EDT 2020
Genetic manipulation of ureteric bud tip progenitors in the mammalian kidney through an Adamts18 enhancer driven tet-on inducible system.
Developmental biology
Rutledge EA,Lindström NO,Michos O,McMahon AP
MA5-15257 was used in Immunocytochemistry to showcase the utility of the Adamts18en-rtTA transgenic model to the investigation of cellular and molecular events specific to branch tip progenitors within the mammalian kidney complementing existing CRE-dependent genetic tools.
Sat Feb 15 00:00:00 EST 2020
Lytic Cell Death Mechanisms in Human Respiratory Syncytial Virus-Infected Macrophages: Roles of Pyroptosis and Necroptosis.
Viruses
Bedient L,Pokharel SM,Chiok KR,Mohanty I,Beach SS,Miura TA,Bose S
Published figure using RFP monoclonal antibody (Product # MA5-15257) in Western Blot
Tue Aug 25 00:00:00 EDT 2020
Expression of a Malassezia Codon Optimized mCherry Fluorescent Protein in a Bicistronic Vector.
Frontiers in cellular and infection microbiology
Goh JPZ,Ianiri G,Heitman J,Dawson TL
Published figure using RFP monoclonal antibody (Product # MA5-15257) in Western Blot
Thu Jun 17 00:00:00 EDT 2021
The netrin receptor UNC-40/DCC assembles a postsynaptic scaffold and sets the synaptic content of GABAA receptors.
Nature communications
Zhou X,Gueydan M,Jospin M,Ji T,Valfort A,Pinan-Lucarré B,Bessereau JL
MA5-15257 was used in Immunoprecipitation to suggest that since DCC is detected at GABA synapses in mammals, DCC might also tune inhibitory neurotransmission in the mammalian brain.
Fri May 29 00:00:00 EDT 2020
The netrin receptor UNC-40/DCC assembles a postsynaptic scaffold and sets the synaptic content of GABAA receptors.
Nature communications
Zhou X,Gueydan M,Jospin M,Ji T,Valfort A,Pinan-Lucarré B,Bessereau JL
MA5-15257 was used in Immunoprecipitation to suggest that since DCC is detected at GABA synapses in mammals, DCC might also tune inhibitory neurotransmission in the mammalian brain.
Fri May 29 00:00:00 EDT 2020
Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia.
Cell reports
Di Nardo A,Lenoël I,Winden KD,Rühmkorf A,Modi ME,Barrett L,Ercan-Herbst E,Venugopal P,Behne R,Lopes CAM,Kleiman RJ,Bettencourt-Dias M,Sahin M
MA5-15257 was used in Immunocytochemistry-immunoflourescence to examine whether neuronal cilia are affected in TSC.
Tue Jun 23 00:00:00 EDT 2020
Interleukin-6 in the central amygdala is bioactive and co-localised with glucagon-like peptide-1 receptor.
Journal of neuroendocrinology
Anesten F,Dalmau Gasull A,Richard JE,Farkas I,Mishra D,Taing L,Zhang F,Poutanen M,Palsdottir V,Liposits Z,Skibicka KP,Jansson JO
MA5-15257 was used in Immunohistochemistry to study the presence of IL-6 in the central amygdala and the effect of interactions between IL-6 and GLPR-1 in the brain.
Sat Jun 01 00:00:00 EDT 2019
A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease.
Nature communications
Sun Q,Lee W,Mohri Y,Takeo M,Lim CH,Xu X,Myung P,Atit RP,Taketo MM,Moubarak RS,Schober M,Osman I,Gay DL,Saur D,Nishimura EK,Ito M
MA5-15257 was used in Immunohistochemistry-immunofluorescence to provide experimental validation of the human melanoma progression model and key insights into the transformation and heterogeneity of McSC-derived melanoma.
Mon Nov 04 00:00:00 EST 2019
SOX2-Dependent Transcription in Clock Neurons Promotes the Robustness of the Central Circadian Pacemaker.
Cell reports
Cheng AH,Bouchard-Cannon P,Hegazi S,Lowden C,Fung SW,Chiang CK,Ness RW,Cheng HM
MA5-15257 was used in Immunohistochemistry-immunofluorescence to show that by defining the transcriptional landscape within SCN neurons, SOX2 enables the generation of robust, entrainable circadian rhythms that accurately reflect environmental time.
Tue Mar 19 00:00:00 EDT 2019
Collective cell migration and metastases induced by an epithelial-to-mesenchymal transition in Drosophila intestinal tumors.
Nature communications
Campbell K,Rossi F,Adams J,Pitsidianaki I,Barriga FM,Garcia-Gerique L,Batlle E,Casanova J,Casali A
MA5-15257 was used in Western Blotting to study the basic mechanisms underlying metastasis and the role of Snail in the formation of macrometastases in Drosophila intestinal tumours.
Fri May 24 00:00:00 EDT 2019
Membrane Localization of HspA1A, a Stress Inducible 70-kDa Heat-Shock Protein, Depends on Its Interaction with Intracellular Phosphatidylserine.
Biomolecules
Bilog AD,Smulders L,Oliverio R,Labanieh C,Zapanta J,Stahelin RV,Nikolaidis N
MA5-15257 was used in Western Blotting to reveal that HspA1A's PM localization and anchorage depend on its selective interaction with intracellular PS.
Wed Apr 17 00:00:00 EDT 2019
Pkd2l1 is required for mechanoception in cerebrospinal fluid-contacting neurons and maintenance of spine curvature.
Nature communications
Sternberg JR,Prendergast AE,Brosse L,Cantaut-Belarif Y,Thouvenin O,Orts-Del'Immagine A,Castillo L,Djenoune L,Kurisu S,McDearmid JR,Bardet PL,Boccara C,Okamoto H,Delmas P,Wyart C
MA5-15257 was used in Immunohistochemistry-immunofluorescence to indicate that cerebrospinal fluid-contacting neurons (CF-CNs) are mechanosensory cells whose Pkd2l1-driven spontaneous activity reflects CSF flow in vivo.
Tue Sep 18 00:00:00 EDT 2018
CRELD1 is an evolutionarily-conserved maturational enhancer of ionotropic acetylcholine receptors.
eLife
D'Alessandro M,Richard M,Stigloher C,Gache V,Boulin T,Richmond JE,Bessereau JL
MA5-15257 was used in Immunoprecipitation to identify CRLD-1A as an evolutionarily-conserved maturational enhancer of ionotropic acetylcholine receptors.
Wed Nov 07 00:00:00 EST 2018
CRELD1 is an evolutionarily-conserved maturational enhancer of ionotropic acetylcholine receptors.
eLife
D'Alessandro M,Richard M,Stigloher C,Gache V,Boulin T,Richmond JE,Bessereau JL
MA5-15257 was used in Immunoprecipitation to identify CRLD-1A as an evolutionarily-conserved maturational enhancer of ionotropic acetylcholine receptors.
Wed Nov 07 00:00:00 EST 2018
Tuning of delta-protocadherin adhesion through combinatorial diversity.
eLife
Bisogni AJ,Ghazanfar S,Williams EO,Marsh HM,Yang JY,Lin DM
MA5-15257 was used in Western Blotting to study how intra- and interfamily delta-protocadherin interactions can greatly amplify the impact of this small subfamily on neuronal function.
Fri Dec 14 00:00:00 EST 2018
Nuclear phosphorylated Dicer processes double-stranded RNA in response to DNA damage.
The Journal of cell biology
Burger K,Schlackow M,Potts M,Hester S,Mohammed S,Gullerova M
MA5-15257 was used in Immunocytochemistry-immunoflourescence to demonstrate a DNA damage-inducible phosphoswitch that causes localized processing of nuclear dsRNA by p-Dicer to promote DNA repair.
Mon Aug 07 00:00:00 EDT 2017
Nuclear phosphorylated Dicer processes double-stranded RNA in response to DNA damage.
The Journal of cell biology
Burger K,Schlackow M,Potts M,Hester S,Mohammed S,Gullerova M
MA5-15257 was used in Immunocytochemistry-immunoflourescence to demonstrate a DNA damage-inducible phosphoswitch that causes localized processing of nuclear dsRNA by p-Dicer to promote DNA repair.
Mon Aug 07 00:00:00 EDT 2017
ARD1-mediated aurora kinase A acetylation promotes cell proliferation and migration.
Oncotarget
Vo TTL,Park JH,Seo JH,Lee EJ,Choi H,Bae SJ,Le H,An S,Lee HS,Wee HJ,Kim KW
Published figure using RFP monoclonal antibody (Product # MA5-15257) in Immunoprecipitation
Tue Aug 22 00:00:00 EDT 2017
ARD1-mediated aurora kinase A acetylation promotes cell proliferation and migration.
Oncotarget
Vo TTL,Park JH,Seo JH,Lee EJ,Choi H,Bae SJ,Le H,An S,Lee HS,Wee HJ,Kim KW
Published figure using RFP monoclonal antibody (Product # MA5-15257) in Immunoprecipitation
Tue Aug 22 00:00:00 EDT 2017
Cholinergic neurons in the dorsomedial hypothalamus regulate food intake.
Molecular metabolism
Jeong JH,Lee DK,Jo YH
MA515257 was used in immunohistochemistry to determine the effects of dorsomedial hypothalamus cholinergic neurons in regulating food intake
Wed Mar 01 00:00:00 EST 2017
Autonomous interconversion between adult pancreatic α-cells and β-cells after differential metabolic challenges.
Molecular metabolism
Ye R,Wang M,Wang QA,Spurgin SB,Wang ZV,Sun K,Scherer PE
Published figure using RFP Tag monoclonal antibody (Product # MA5-15257) in Immunofluorescence
Fri Jul 01 00:00:00 EDT 2016
TRPV4-Mediated Detection of Hyposmotic Stress by Skin Keratinocytes Activates Developmental Immunity.
Journal of immunology (Baltimore, Md. : 1950)
Galindo-Villegas J,Montalban-Arques A,Liarte S,de Oliveira S,Pardo-Pastor C,Rubio-Moscardo F,Meseguer J,Valverde MA,Mulero V
MA5-15257 was used in immunohistochemistry to report that osmotic stress regulates the activation of immunity in neonatal zebrafish
Fri Jan 15 00:00:00 EST 2016
DREADD in parvalbumin interneurons of the dentate gyrus modulates anxiety, social interaction and memory extinction.
Current molecular medicine
Zou D,Chen L,Deng D,Jiang D,Dong F,McSweeney C,Zhou Y,Liu L,Chen G,Wu Y,Mao Y
MA5-15257 was used in Immunohistochemistry to investigate the functional role of parvalbumin-positive interneurons in the mouse hippocampus using designer receptors exclusively activated by designer drugs (DREADD) technology.
Wed Oct 05 00:00:00 EDT 2016
LIG4 mediates Wnt signalling-induced radioresistance.
Nature communications
Jun S,Jung YS,Suh HN,Wang W,Kim MJ,Oh YS,Lien EM,Shen X,Matsumoto Y,McCrea PD,Li L,Chen J,Park JI
MA5-15257 was used in immunohistochemistry to learn mediation of Wnt signaling-induced radioresistance by LIG4
Thu Mar 24 00:00:00 EDT 2016
Phosphorylated STAT5 regulates p53 expression via BRCA1/BARD1-NPM1 and MDM2.
Cell death & disease
Ren Z,Aerts JL,Vandenplas H,Wang JA,Gorbenko O,Chen JP,Giron P,Heirman C,Goyvaerts C,Zacksenhaus E,Minden MD,Stambolic V,Breckpot K,De Grève J
MA515257 was used in western blot to elucidate a mutually regulatory relationship between signal transducer and activator of transcription 5 and nucleophosmin
Thu Dec 22 00:00:00 EST 2016
Tnfa signaling through tnfr2 protects skin against oxidative stress-induced inflammation.
PLoS biology
Candel S,de Oliveira S,López-Muñoz A,García-Moreno D,Espín-Palazón R,Tyrkalska SD,Cayuela ML,Renshaw SA,Corbalán-Vélez R,Vidal-Abarca I,Tsai HJ,Meseguer J,Sepulcre MP,Mulero V
Published figure using RFP Tag monoclonal antibody (Product # MA5-15257) in Immunofluorescence
Thu May 01 00:00:00 EDT 2014
