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Product Details
PA5-101835
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RGS5(Accession O15539), corresponding to amino acid residues I21-N71.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2851267
Product Specific Information
Antibody detects endogenous levels of total RGS5.
Target Information
The regulator of G protein signaling (RGS) proteins are signal transduction molecules that have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. Multiple genes homologous to SST2 are present in higher eukaryotes. RGS proteins are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. The mRNA of the human gene is abundantly expressed in heart, lung, skeletal muscle, and small intestine, and at low levels in brain, placenta, liver, colon, and leukocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: regulator of G protein signaling 5; Regulator of G-protein signaling 5; RGS-5; RGS5; RP11-430G6.2
Gene Aliases: 1110070A02Rik; MST092; MST106; MST129; MSTP032; MSTP092; MSTP106; MSTP129; RGS5
UniProt ID: (Human) O15539, (Mouse) O08850, (Rat) P49800
Entrez Gene ID: (Human) 8490, (Mouse) 19737, (Rat) 54294
regulation of G-protein coupled receptor protein signaling pathway
negative regulation of signal transduction
positive regulation of GTPase activity
signal transduction
G-protein coupled receptor signaling pathway
termination of G-protein coupled receptor signaling pathway
negative regulation of G-protein coupled receptor protein signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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