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Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Inactive rhomboid protein 2; iRhom2; Rhomboid 5 homolog 2; Rhomboid family member 2; Rhomboid veinlet-like protein 5; Rhomboid veinlet-like protein 6; rhomboid, veinlet-like 6; rhomboid-like protein 6; Rhomboid-related protein
Gene Aliases: 4732465I17Rik; cub; IRHOM2; RHBDF2; RHBDL5; RHBDL6; Rhor; TEC; TOC; TOCG
UniProt ID: (Human) Q6PJF5, (Mouse) Q80WQ6
Entrez Gene ID: (Human) 79651, (Mouse) 217344
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