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Product Details
TA806448
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI3A5
Immunogen
Synthetic peptide: VFEMATRAGLQVRKNKRRRG, corresponding to C terminal of human RHOC.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
RhoC is part of blood-group antigens that are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AR ARHC; h9; MGC1448; MGC61427; oncogene RHO H9; ras homolog gene family, member C; RAS-related homolog 9; Rho; Rho cDNA clone 9; RHO MGC1448; Rho-related GTP-binding protein RhoC; rhoC GTPase; small GTP binding protein RhoC
Gene Aliases: ARH9; ARHC; H9; RHOC; RHOH9
UniProt ID: (Human) P08134
Entrez Gene ID: (Human) 389
cytokinesis
small GTPase mediated signal transduction
positive regulation of I-kappaB kinase/NF-kappaB signaling
apical junction assembly
wound healing, spreading of cells
regulation of small GTPase mediated signal transduction
positive regulation of lipase activity
skeletal muscle satellite cell migration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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