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Product Details
PA5-21582
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region within amino acids 1648 and 1708 of RICTOR (Uniprot ID#Q6R327)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_11157053
Product Specific Information
Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
RICTOR and MTOR (FRAP1) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AVO3 homolog; DKFZp686B11164; hAVO3; MGC39830; pianissimo; Rapamycin-insensitive companion of mTOR; RICTOR; RPTOR independent companion of MTOR, complex 2; TORC2-specific protein AVO3
Gene Aliases: AVO3; hAVO3; KIAA1999; PIA; RICTOR
UniProt ID: (Human) Q6R327
Entrez Gene ID: (Human) 253260
positive regulation of endothelial cell proliferation
embryo development
regulation of gene expression
peptidyl-serine phosphorylation
establishment of cell polarity
positive regulation of actin filament polymerization
establishment or maintenance of actin cytoskeleton polarity
T cell costimulation
actin cytoskeleton reorganization
TOR signaling
positive regulation of TOR signaling
regulation of actin cytoskeleton organization
regulation of peptidyl-serine phosphorylation
regulation of phosphorylation
positive regulation of catalytic activity
regulation of GTPase activity
phosphatidylinositol-mediated signaling
regulation of inflammatory response
positive regulation of peptidyl-tyrosine phosphorylation
regulation of protein kinase B signaling
positive regulation of protein kinase B signaling
regulation of establishment of cell polarity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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