Product References
The Potential of Dendritic-Cell-Based Vaccines to Modulate Type 3 Innate Lymphoid Cell Populations.
International journal of molecular sciences
Chan L,Mehrani Y,Minott JA,Bridle BW,Karimi K
17-6988-82 was used in Flow cytometry/Cell sorting to explore the communications between type 3 ILCs (ILC3s) and DCs using a murine model of DC-based vaccination.
Thu Jan 26 00:00:00 EST 2023
Maturation and specialization of group 2 innate lymphoid cells through the lung-gut axis.
Nature communications
Zhao M,Shao F,Yu D,Zhang J,Liu Z,Ma J,Xia P,Wang S
17-6988-82 was used in Flow cytometry/Cell sorting to show that ILC2s undergo translocation via the lung-gut axis upon IL-33 treatment.
Fri Dec 09 00:00:00 EST 2022
RAGE-mediated T cell metabolic reprogramming shapes T cell inflammatory response after stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Zhang Y,Li F,Chen C,Li Y,Xie W,Huang D,Zhai X,Yu W,Wan J,Li P
17-6988-82 was used in Flow cytometry/Cell sorting to show that sRAGE can serve as a novel immunometabolic modulator that ameliorates ischemic stroke recovery by inhibiting fatty acid synthesis and thus favoring CD4+ T cells polarization toward Treg after cerebral ischemia injury.
Wed Jun 01 00:00:00 EDT 2022
Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition).
European journal of immunology
Cossarizza A,Chang HD,Radbruch A,Abrignani S,Addo R,Akdis M,Andrä I,Andreata F,Annunziato F,Arranz E,Bacher P,Bari S,Barnaba V,Barros-Martins J,Baumjohann D,Beccaria CG,Bernardo D,Boardman DA,Borger J,Böttcher C,Brockmann L,Burns M,Busch DH,Cameron G,Cammarata I,Cassotta A,Chang Y,Chirdo FG,Christakou E,Čičin-Šain L,Cook L,Corbett AJ,Cornelis R,Cosmi L,Davey MS,De Biasi S,De Simone G,Del Zotto G,Delacher M,Di Rosa F,Di Santo J,Diefenbach A,Dong J,Dörner T,Dress RJ,Dutertre CA,Eckle SBG,Eede P,Evrard M,Falk CS,Feuerer M,Fillatreau S,Fiz-Lopez A,Follo M,Foulds GA,Fröbel J,Gagliani N,Galletti G,Gangaev A,Garbi N,Garrote JA,Geginat J,Gherardin NA,Gibellini L,Ginhoux F,Godfrey DI,Gruarin P,Haftmann C,Hansmann L,Harpur CM,Hayday AC,Heine G,Hernández DC,Herrmann M,Hoelsken O,Huang Q,Huber S,Huber JE,Huehn J,Hundemer M,Hwang WYK,Iannacone M,Ivison SM,Jäck HM,Jani PK,Keller B,Kessler N,Ketelaars S,Knop L,Knopf J,Koay HF,Kobow K,Kriegsmann K,Kristyanto H,Krueger A,Kuehne JF,Kunze-Schumacher H,Kvistborg P,Kwok I,Latorre D,Lenz D,Levings MK,Lino AC,Liotta F,Long HM,Lugli E,MacDonald KN,Maggi L,Maini MK,Mair F,Manta C,Manz RA,Mashreghi MF,Mazzoni A,McCluskey J,Mei HE,Melchers F,Melzer S,Mielenz D,Monin L,Moretta L,Multhoff G,Muñoz LE,Muñoz-Ruiz M,Muscate F,Natalini A,Neumann K,Ng LG,Niedobitek A,Niemz J,Almeida LN,Notarbartolo S,Ostendorf L,Pallett LJ,Patel AA,Percin GI,Peruzzi G,Pinti M,Pockley AG,Pracht K,Prinz I,Pujol-Autonell I,Pulvirenti N,Quatrini L,Quinn KM,Radbruch H,Rhys H,Rodrigo MB,Romagnani C,Saggau C,Sakaguchi S,Sallusto F,Sanderink L,Sandrock I,Schauer C,Scheffold A,Scherer HU,Schiemann M,Schildberg FA,Schober K,Schoen J,Schuh W,Schüler T,Schulz AR,Schulz S,Schulze J,Simonetti S,Singh J,Sitnik KM,Stark R,Starossom S,Stehle C,Szelinski F,Tan L,Tarnok A,Tornack J,Tree TIM,van Beek JJP,van de Veen W,van Gisbergen K,Vasco C,Verheyden NA,von Borstel A,Ward-Hartstonge KA,Warnatz K,Waskow C,Wiedemann A,Wilharm A,Wing J,Wirz O,Wittner J,Yang JHM,Yang J
17-6988-82 was used in Flow cytometry/Cell sorting to provide the key aspects to consider when performing flow cytometry experiments.
Wed Dec 01 00:00:00 EST 2021
Butyrophilin-like 2 regulates site-specific adaptations of intestinal γδ intraepithelial lymphocytes.
Communications biology
Panea C,Zhang R,VanValkenburgh J,Ni M,Adler C,Wei Y,Ochoa F,Schmahl J,Tang Y,Siao CJ,Poueymirou W,Espert J,Lim WK,Atwal GS,Murphy AJ,Sleeman MA,Hovhannisyan Z,Haxhinasto S
17-6988-82 was used in Flow Cytometry to show that Btnl2 suppressed homeostatic proliferation of γδ IELs preferentially in the ileum.
Mon Jul 26 00:00:00 EDT 2021
AMPK induces regulatory innate lymphoid cells after traumatic brain injury.
JCI insight
Baban B,Braun M,Khodadadi H,Ward A,Alverson K,Malik A,Nguyen K,Nazarian S,Hess DC,Forseen S,Post AF,Vale FL,Vender JR,Hoda MN,Akbari O,Vaibhav K,Dhandapani KM
17-6988 was used in Flow cytometry/Cell sorting to identify AMPK as a brake on the expansion of proinflammatory, CNS-resident ILCs after brain injury.
Mon Jan 11 00:00:00 EST 2021
Small-molecule antagonist of VLA-4 (GW559090) attenuated neuro-inflammation by targeting Th17 cell trafficking across the blood-retinal barrier in experimental autoimmune uveitis.
Journal of neuroinflammation
Chen YH,Eskandarpour M,Zhang X,Galatowicz G,Greenwood J,Lightman S,Calder V
17-6988-82 was used in Flow Cytometry to show that the α4β1 integrin inhibitor may exert a modulatory effect in EAU progression by selectively blocking Th17 cell migration across the blood-retinal barrier without affecting systemic CD4+ T cell subsets.
Thu Feb 18 00:00:00 EST 2021
Chronic exposure to IL-6 induces a desensitized phenotype of the microglia.
Journal of neuroinflammation
Recasens M,Almolda B,Pérez-Clausell J,Campbell IL,González B,Castellano B
17-6988-82 was used in Flow Cytometry to evaluate the effects of chronic IL-6 production on the immune response associated with CNS-axonal anterograde degeneration.
Fri Jan 22 00:00:00 EST 2021
Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity.
Immunity
DiToro D,Harbour SN,Bando JK,Benavides G,Witte S,Laufer VA,Moseley C,Singer JR,Frey B,Turner H,Bruning J,Darley-Usmar V,Gao M,Conover C,Hatton RD,Frank S,Colonna M,Weaver CT
17-6988 was used in Flow cytometry/Cell sorting to show that, among effector T cell subsets, Th17 and Treg cells selectively expressed multiple components of the IGF system.
Tue Apr 14 00:00:00 EDT 2020
Combined Prebiotic and Microbial Intervention Improves Oral Cholera Vaccination Responses in a Mouse Model of Childhood Undernutrition.
Cell host & microbe
Di Luccia B,Ahern PP,Griffin NW,Cheng J,Guruge JL,Byrne AE,Rodionov DA,Leyn SA,Osterman AL,Ahmed T,Colonna M,Barratt MJ,Delahaye NF,Gordon JI
17-6988-82 was used in Flow Cytometry to provide preclinical proof-of-concept that diet and microbiota influence mucosal immune responses to CT vaccination and identify a candidate synbiotic formulation.
Wed Jun 10 00:00:00 EDT 2020
Bendamustine with total body irradiation conditioning yields tolerant T-cells while preserving T-cell-dependent graft-versus-leukemia.
Oncoimmunology
Stokes J,Hoffman EA,Molina MS,Kummet N,Simpson RJ,Zeng Y,Katsanis E
17-6988 was used in Flow cytometry/Cell sorting to demonstrate that BEN-TBI reduces graft-versus-host disease (GvHD) compared to CY-TBI independently of T regulatory cells (Tregs).
Wed Jul 14 00:00:00 EDT 2021
Adjuvant-free nanofiber vaccine induces in situ lung dendritic cell activation and TH17 responses.
Science advances
Si Y,Tian Q,Zhao F,Kelly SH,Shores LS,Camacho DF,Sperling AI,Andrade MS,Collier JH,Chong AS
17-6988 was used in Flow cytometry/Cell sorting to show that antigens displayed on self-assembling nanofiber scaffolds and delivered intranasally are presented by CD103+ and CD11b+ lung dendritic cells that up-regulate CD80 and migrate into the draining lymph node (LN).
Sat Aug 01 00:00:00 EDT 2020
Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation.
Cancer cell
Segovia M,Russo S,Jeldres M,Mahmoud YD,Perez V,Duhalde M,Charnet P,Rousset M,Victoria S,Veigas F,Louvet C,Vanhove B,Floto RA,Anegon I,Cuturi MC,Girotti MR,Rabinovich GA,Hill M
17-6988 was used in Flow cytometry/Cell sorting to dentify BayK8644 as a potent TMEM176B inhibitor that promotes CD8+ T cell-mediated tumor control and reinforces the antitumor activity of both anti-CTLA-4 and anti-PD-1 antibodies.
Mon May 13 00:00:00 EDT 2019
Loss of Antigen Presentation in Adipose Tissue Macrophages or in Adipocytes, but Not Both, Improves Glucose Metabolism.
Journal of immunology (Baltimore, Md. : 1950)
Blaszczak AM,Wright VP,Anandani K,Liu J,Jalilvand A,Bergin S,Nicoloro SM,Czech MP,Lafuse W,Deng T,Bradley D,Hsueh WA
17-6988 was used in Flow cytometry/Cell sorting to show systemic glucose metabolism can be improved by individual loss of adipose tissue macrophages or adipocyte APC.
Mon Apr 15 00:00:00 EDT 2019
Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced Colitis.
Cell reports
Wang B,Lim JH,Kajikawa T,Li X,Vallance BA,Moutsopoulos NM,Chavakis T,Hajishengallis G
17-6988 was used in Flow cytometry/Cell sorting to conclude that β2-integrins are required for protective IL-1β-dependent IL-22 responses in colitis, and the identified mechanism may underlie the association of human LAD1 with colitis.
Tue Feb 05 00:00:00 EST 2019
Proteomic Analyses of Human Regulatory T Cells Reveal Adaptations in Signaling Pathways that Protect Cellular Identity.
Immunity
Cuadrado E,van den Biggelaar M,de Kivit S,Chen YY,Slot M,Doubal I,Meijer A,van Lier RAW,Borst J,Amsen D
17-6988 was used in Flow cytometry/Cell sorting to suggest that adaptation in signaling pathways protect Treg cell identity and present a resource for further research into Treg cell biology.
Tue May 15 00:00:00 EDT 2018
The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling.
Cell metabolism
Ricciardi S,Manfrini N,Alfieri R,Calamita P,Crosti MC,Gallo S,Müller R,Pagani M,Abrignani S,Biffo S
17-6988 was used in Flow cytometry/Cell sorting to discover that T cells fulfill this transitional process through translational control.
Tue Dec 04 00:00:00 EST 2018
CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response.
Cell metabolism
Chatterjee S,Daenthanasanmak A,Chakraborty P,Wyatt MW,Dhar P,Selvam SP,Fu J,Zhang J,Nguyen H,Kang I,Toth K,Al-Homrani M,Husain M,Beeson G,Ball L,Helke K,Husain S,Garrett-Mayer E,Hardiman G,Mehrotra M,Nishimura MI,Beeson CC,Bupp MG,Wu J,Ogretmen B,Paulos CM,Rathmell J,Yu XZ,Mehrotra S
17-6988 was used in Flow cytometry/Cell sorting to establish ex vivo culture conditions to generate hybrid Th1/17 cells, which persist long-term in vivo while maintaining effector function.
Tue Jan 09 00:00:00 EST 2018
The CXC Chemokine Receptor 3 Inhibits Autoimmune Cholangitis via CD8+ T Cells but Promotes Colitis via CD4+ T Cells.
Frontiers in immunology
Liu QZ,Ma WT,Yang JB,Zhao ZB,Yan K,Yao Y,Li L,Miao Q,Gershwin ME,Lian ZX
17-6988 was used in Flow cytometry/Cell sorting to explore the function of CXCR3 in the modulation of different organ-specific autoimmune diseases in interleukin receptor deficient mice.
Fri Jul 26 00:00:00 EDT 2019
Influenza-Activated ILC1s Contribute to Antiviral Immunity Partially Influenced by Differential GITR Expression.
Frontiers in immunology
Vashist N,Trittel S,Ebensen T,Chambers BJ,Guzmán CA,Riese P
17-6988 was used in Flow cytometry/Cell sorting to discover the regulation behind ILC1s during infection and their capacity to interact with cells of the adaptive immune system.
Fri May 10 00:00:00 EDT 2019
Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation.
Cell
Lim AI,Li Y,Lopez-Lastra S,Stadhouders R,Paul F,Casrouge A,Serafini N,Puel A,Bustamante J,Surace L,Masse-Ranson G,David E,Strick-Marchand H,Le Bourhis L,Cocchi R,Topazio D,Graziano P,Muscarella LA,Rogge L,Norel X,Sallenave JM,Allez M,Graf T,Hendriks RW,Casanova JL,Amit I,Yssel H,Di Santo JP
17-6988 was used in Flow cytometry/Cell sorting to identify circulating and tissue ILC precursors in humans that fail to express the transcription factors and cytokine outputs of mature ILCs but have these signature loci in an epigenetically poised configuration.
Thu Mar 09 00:00:00 EST 2017
The microvascular niche instructs T cells in large vessel vasculitis via the VEGF-Jagged1-Notch pathway.
Science translational medicine
Wen Z,Shen Y,Berry G,Shahram F,Li Y,Watanabe R,Liao YJ,Goronzy JJ,Weyand CM
Wed Jul 19 00:00:00 EDT 2017
Inducible and naturally occurring regulatory T cells enhance lung allergic responses through divergent transcriptional pathways.
The Journal of allergy and clinical immunology
Joetham A,Schedel M,O'Connor BP,Kim S,Takeda K,Abbott J,Gelfand EW
17-6988 was used in Flow cytometry/Cell sorting to study the differences between the pathways leading to enhancement of lung allergic responses by both transferred naturally occurring regulatory T and inducible regulatory T cells.
Sat Apr 01 00:00:00 EDT 2017
Protein kinase CK2 controls T-cell polarization through dendritic cell activation in response to contact sensitizers.
Journal of leukocyte biology
de Bourayne M,Gallais Y,El Ali Z,Rousseau P,Damiens MH,Cochet C,Filhol O,Chollet-Martin S,Pallardy M,Kerdine-Römer S
17-6988-82 was used in Flow Cytometry to identify protein kinase CK2 as a novel kinase involved in the activation of human monocyte-derived DCs (MoDCs) in response to NiSO4 and 2,4-dinitrochlorobenzene (DNCB).
Wed Mar 01 00:00:00 EST 2017
Bilirubin suppresses Th17 immunity in colitis by upregulating CD39.
JCI insight
Longhi MS,Vuerich M,Kalbasi A,Kenison JE,Yeste A,Csizmadia E,Vaughn B,Feldbrugge L,Mitsuhashi S,Wegiel B,Otterbein L,Moss A,Quintana FJ,Robson SC
17-6988 was used in Flow cytometry/Cell sorting to discover that the immunosuppressive effects of unconjugated bilirubinare mediated by an aryl hydrocarbon receptor results in CD39 upregulation by Th17.
Thu May 04 00:00:00 EDT 2017
High salt diet stimulates gut Th17 response and exacerbates TNBS-induced colitis in mice.
Oncotarget
Wei Y,Lu C,Chen J,Cui G,Wang L,Yu T,Yang Y,Wu W,Ding Y,Li L,Uede T,Chen Z,Diao H
17698882 was used in flow cytometry to determine the effect of a high salt diet on intestinal immunity and the risk of inflammatory bowel disease
Tue Jan 03 00:00:00 EST 2017
Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth.
Oncogene
De Simone V,Franzè E,Ronchetti G,Colantoni A,Fantini MC,Di Fusco D,Sica GS,Sileri P,MacDonald TT,Pallone F,Monteleone G,Stolfi C
17-6988 was used in Flow cytometry/Cell sorting to explore cotargeting of STAT3 and NF-kB as a novel approach to combat colorectal cancers.
Wed Jul 01 00:00:00 EDT 2015
The pathogenic Th profile of human activated memory Th cells in early rheumatoid arthritis can be modulated by VIP.
Journal of molecular medicine (Berlin, Germany)
Jimeno R,Gomariz RP,Garín M,Gutiérrez-Cañas I,González-Álvaro I,Carrión M,Galindo M,Leceta J,Juarranz Y
17-6988 was used in Flow cytometry/Cell sorting to analyse the pathogenic Th17 and Th17/1 profile of memory Th cells after in vitro activation/expansion in early rheumatoid arthritis patients.
Wed Apr 01 00:00:00 EDT 2015
Skewed T-helper (Th)1/2- and Th17/T regulatory‑cell balances in patients with renal cell carcinoma.
Molecular medicine reports
Li L,Yang C,Zhao Z,Xu B,Zheng M,Zhang C,Min Z,Guo J,Rong R
17-6988 was used in Flow cytometry/Cell sorting to demonstrate that the balance of Th1 and Th2 cells is skewed towards the Th2 profile in the peripheral blood of patients with RCC.
Sun Feb 01 00:00:00 EST 2015
NCR(+)ILC3 concentrate in human lung cancer and associate with intratumoral lymphoid structures.
Nature communications
Carrega P,Loiacono F,Di Carlo E,Scaramuccia A,Mora M,Conte R,Benelli R,Spaggiari GM,Cantoni C,Campana S,Bonaccorsi I,Morandi B,Truini M,Mingari MC,Moretta L,Ferlazzo G
17-6988 was used in Flow cytometry/Cell sorting to investigate the role of the NCR(+) ILC-3 in non-small cell lung cancer.
Wed Sep 23 00:00:00 EDT 2015
MicroRNA-155 is essential for T(H)2-mediated allergen-induced eosinophilic inflammation in the lung.
The Journal of allergy and clinical immunology
Malmhäll C,Alawieh S,Lu Y,Sjöstrand M,Bossios A,Eldh M,Rådinger M
17-6988 was used in Flow cytometry/Cell sorting to investigate the contribution of microRNA-155 to TH2-mediated allergen-induced airway inflammation in a mouse model.
Thu May 01 00:00:00 EDT 2014
Regulatory T cells promote a protective Th17-associated immune response to intestinal bacterial infection with C. rodentium.
Mucosal immunology
Wang Z,Friedrich C,Hagemann SC,Korte WH,Goharani N,Cording S,Eberl G,Sparwasser T,Lochner M
17-6988 was used in Flow cytometry/Cell sorting to study the impact of Foxp3(+) Tregs on inflammatory processes elicited by the bacterial pathogen C. rodentium, showing that Tregs promote a protective Th17-associated immune response.
Sat Nov 01 00:00:00 EDT 2014
High-dose interferon-γ promotes abortion in mice by suppressing Treg and Th17 polarization.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Liu HY,Liu ZK,Chao H,Li Z,Song Z,Yang Y,Peng JP
17-6988 was used in Immunohistochemistry to demonstrate that in murine pregnancy, a supraphysiological dose of IFN-γ could induce peri-implantation failure.
Thu May 01 00:00:00 EDT 2014
Rag2-deficient IL-1 Receptor Antagonist-deficient Mice Are a Novel Colitis Model in Which Innate Lymphoid Cell-derived IL-17 Is Involved in the Pathogenesis.
Experimental animals
Akitsu A,Kakuta S,Saijo S,Iwakura Y
17-6988 was used in Flow cytometry/Cell sorting to explore the relationship between IL-17A-producing cells and Treg cells in immune homeostasis of the colon.
Wed Oct 22 00:00:00 EDT 2014
Bhlhe40 controls cytokine production by T cells and is essential for pathogenicity in autoimmune neuroinflammation.
Nature communications
Lin CC,Bradstreet TR,Schwarzkopf EA,Sim J,Carrero JA,Chou C,Cook LE,Egawa T,Taneja R,Murphy TL,Russell JH,Edelson BT
17-6988 was used in Flow cytometry/Cell sorting to study the factors affecting pathogenicity of TH cells in experimental autoimmune encephalomyelitis (EAE), showing that Bhlhe40 controls cytokine production by T cells and is essential for pathogenicity in EAE.
Thu Apr 03 00:00:00 EDT 2014
Protein kinase C θ regulates the phenotype of murine CD4+ Th17 cells.
PloS one
Wachowicz K,Hermann-Kleiter N,Meisel M,Siegmund K,Thuille N,Baier G
17-6988 was used in Flow cytometry/Cell sorting to suggest that PKCh is critical for stabilizing Th17 cell phenotype by suppresing the STAT4/IFN-c/T-bet axis at the onset of differentiation.
Tue Jun 23 00:00:00 EDT 2015
Small intestinal intraepithelial TCRγδ+ T lymphocytes are present in the premature intestine but selectively reduced in surgical necrotizing enterocolitis.
PloS one
Weitkamp JH,Rosen MJ,Zhao Z,Koyama T,Geem D,Denning TL,Rock MT,Moore DJ,Halpern MD,Matta P,Denning PW
17-6988 was used in Flow cytometry/Cell sorting to study the development of γδ intraepithelial lymphocytes in the ileum of human infants and examine their role in pathogenesis of necrotizing enterocolitis.
Tue Oct 06 00:00:00 EDT 2015
n3 PUFAs reduce mouse CD4+ T-cell ex vivo polarization into Th17 cells.
The Journal of nutrition
Monk JM,Hou TY,Turk HF,McMurray DN,Chapkin RS
17-6988 was used in Flow cytometry/Cell sorting to discern the effect of n3 PUFAs on the CD4+ T-cells of mice.
Sun Sep 01 00:00:00 EDT 2013
Colonic immune stimulation by targeted oral vaccine.
PloS one
Kathania M,Zadeh M,Lightfoot YL,Roman RM,Sahay B,Abbott JR,Mohamadzadeh M
17-6988 was used in Flow cytometry/Cell sorting to suggest that L. gasseri expressing PA-DCpep has immunopotentiating properties, by inducing humoral and T cell-mediated immune responses upon oral administration.
Fri Jul 19 00:00:00 EDT 2013
Stromal cells induce Th17 during Helicobacter pylori infection and in the gastric tumor microenvironment.
PloS one
Pinchuk IV,Morris KT,Nofchissey RA,Earley RB,Wu JY,Ma TY,Beswick EJ
17-6988 was used in Flow cytometry/Cell sorting to investigate the role of Th17 cells are CD4(+) T cells during Helicobacter pylori-associated gastric carcinogenesis.
Mon Jul 08 00:00:00 EDT 2013
Th17 effector cells support B cell responses outside of germinal centres.
PloS one
Patakas A,Benson RA,Withers DR,Conigliaro P,McInnes IB,Brewer JM,Garside P
17-6988 was used in Flow cytometry/Cell sorting to investigate the role of Th17 cells in the development of a humoral immune response using T and B cell receptor transgenic mice.
Thu Jun 20 00:00:00 EDT 2013
Defining early human NK cell developmental stages in primary and secondary lymphoid tissues.
PloS one
Eissens DN,Spanholtz J,van der Meer A,van Cranenbroek B,Dolstra H,Kwekkeboom J,Preijers FW,Joosten I
17-6988 was used in Flow cytometry/Cell sorting to study how differential in situ NK cell development and trafficking towards multiple tissues may give rise to a broad spectrum of mature NK cell subsets found within the human body.
Mon Sep 24 00:00:00 EDT 2012
Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus.
Arthritis research & therapy
Dolff S,Abdulahad WH,Westra J,Doornbos-van der Meer B,Limburg PC,Kallenberg CG,Bijl M
17-6988 was used in Flow cytometry/Cell sorting to reveal a pivotal role of IL-21 in the pathogenesis of SLE.
Thu Dec 13 00:00:00 EST 2012
IL-1β-mediated signals preferentially drive conversion of regulatory T cells but not conventional T cells into IL-17-producing cells.
Journal of immunology (Baltimore, Md. : 1950)
Li L,Kim J,Boussiotis VA
Fri Oct 01 00:00:00 EDT 2010
Cutting edge: IL-7 regulates the peripheral pool of adult ROR gamma+ lymphoid tissue inducer cells.
Journal of immunology (Baltimore, Md. : 1950)
Schmutz S,Bosco N,Chappaz S,Boyman O,Acha-Orbea H,Ceredig R,Rolink AG,Finke D
Sat Aug 15 00:00:00 EDT 2009
Lack of IL-6 during coxsackievirus infection heightens the early immune response resulting in increased severity of chronic autoimmune myocarditis.
PloS one
Poffenberger MC,Straka N,El Warry N,Fang D,Shanina I,Horwitz MS
Thu Jul 09 00:00:00 EDT 2009
