Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This antibody is predicted to react with canine and human based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
RPE65 is a major protein of the retinal pigment epithelium (RPE). RPE65 is essential for the regeneration of rhodopsin in the visual cycle. Mutations in RPE65 are responsible for certain forms of autosomal recessive severe retinal dystrophy, including Leber Congenital Amaurosis (LCA). Loss of function results in a block in retinoid processing required for the synthesis of 11-cis retinal and the accumulation of retinyl esters in the RPE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: All-trans-retinyl-palmitate hydrolase; Lutein isomerase; Meso-zeaxanthin isomerase; retinal pigment epithelium 65-like; Retinal pigment epithelium-specific 65 kDa protein; Retinitis pigmentos; Retinoid isomerohydrolase; Retinol isomerase
Gene Aliases: Rpe65
UniProt ID: (Rat) O70276
Entrez Gene ID: (Rat) 89826
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