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FIGURE: 1 / 7
Recommended positive controls: 293T, NIH-3T3, Raw264.7, C2C12.
Predicted reactivity: Mouse (97%), Rat (97%), Zebrafish (87%), Xenopus laevis (86%), Chicken (92%), Rhesus Monkey (98%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
RRM1 (Ribonucleotide reductase M1 polypeptide) is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is involved in carcinogenesis, tumor progression.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: R RRM 1; RI RI RR 1; Ribonucleoside-diphosphate reductase large subunit; Ribonucleoside-diphosphate reductase subunit M1; Ribonucleotide reductase large subunit; ribonucleotide reductase M1 polypeptide; ribonucleotide reductase, R1 subunit; RIR 1
Gene Aliases: R1; RIR1; RnrM1; RR1; RRM1
UniProt ID: (Human) P23921, (Mouse) P07742
Entrez Gene ID: (Human) 6240, (Mouse) 20133
Molecular Function:
oxidoreductase
reductase
metabolite interconversion enzyme
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