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MA1-7079 detects the Rabies virus. This monoclonal antibody is broadly reactive with over 20 different strains including: Duwenhage, Mokola & Lagosbat.
MA1-7079 has been successfully used in ELISA, immunofluorescence, and immunocytochemistry procedures.
The MA1-7079 immunogen is Rabies virus lysate. This antibody is specific for a surface glycoprotein.
Rabies virus (Neurotropic lyssavirus) is a member of the Rhabdoviridae family. Rabies is a single stranded, neurotropic, negative sense RNA virus which encodes 5 proteins: a glycoprotein, a nucleoprotein, and three others. The mature virus has a bullet shape, a protein coat, and a lipid envelope. The outer surface of the virus is covered with thumblike glycoprotein projections 5-10 nm long and 3 nm in diameter. The virus averages approximately 780 nm in length. Virus infectivity is destroyed by lipid solvents. Rabies virus is a very successful virus, with a very wide range of hosts. It causes an acute, central nervous system infection, characterized by CNS irritation, followed by paralysis and death. Approximately 50,000 human deaths each year are caused by rabies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Neurotropic lyssavirus
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