Product References
Arsenic interferes with spermatogenesis involving Rictor/mTORC2-mediated blood-testis barrier disruption in mice.
Ecotoxicology and environmental safety
Li X,Wang W,Hou Y,Li G,Yi H,Cui S,Zhang J,He X,Zhao H,Yang Z,Qiu Y,Liu Z,Xie J
Thu Jun 01 00:00:00 EDT 2023
Interleukin 6 promotes BMP9-induced osteoblastic differentiation through Stat3/mTORC1 in mouse embryonic fibroblasts.
Aging
Wang SY,Jiang JH,Liu SY,Zhang J,Gao X,Liu H,Ke KX,Jiang Y,Liu L,He BC
Wed Feb 01 00:00:00 EST 2023
Tetrathiomolybdate Decreases the Expression of Alkaline Phosphatase in Dermal Papilla Cells by Increasing Mitochondrial ROS Production.
International journal of molecular sciences
Li F,Liu H,Wu X,Song Z,Tang H,Gong M,Liu L,Li F
Sat Feb 04 00:00:00 EST 2023
TBK1 Knockdown Alleviates Axonal Transport Deficits in Retinal Ganglion Cells Via mTORC1 Activation in a Retinal Damage Mouse Model.
Investigative ophthalmology & visual science
Ye M,Hu Y,Zhao B,Mou Q,Ni Y,Luo J,Li L,Zhang H,Zhao Y
Mon Jul 03 00:00:00 EDT 2023
TBK1 Knockdown Alleviates Axonal Transport Deficits in Retinal Ganglion Cells Via mTORC1 Activation in a Retinal Damage Mouse Model.
Investigative ophthalmology & visual science
Ye M,Hu Y,Zhao B,Mou Q,Ni Y,Luo J,Li L,Zhang H,Zhao Y
Mon Jul 03 00:00:00 EDT 2023
NUMB facilitates autophagy initiation through targeting SCFβ-TrCP2 complex.
Cell death and differentiation
Li H,Shu S,Zhou M,Chen Y,Xiao A,Ma Y,Zhu F,Hu Z,Nie J
Fri Jul 01 00:00:00 EDT 2022
Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion.
Nature
Wang JQ,Li LL,Hu A,Deng G,Wei J,Li YF,Liu YB,Lu XY,Qiu ZP,Shi XJ,Zhao X,Luo J,Song BL
Mon Aug 01 00:00:00 EDT 2022
Effects of Bisphenol A on reproductive toxicity and gut microbiota dysbiosis in male rats.
Ecotoxicology and environmental safety
Liu R,Cai D,Li X,Liu B,Chen J,Jiang X,Li H,Li Z,Teerds K,Sun J,Bai W,Jin Y
Fri Jul 01 00:00:00 EDT 2022
N7-methylguanosine tRNA modification promotes esophageal squamous cell carcinoma tumorigenesis via the RPTOR/ULK1/autophagy axis.
Nature communications
Han H,Yang C,Ma J,Zhang S,Zheng S,Ling R,Sun K,Guo S,Huang B,Liang Y,Wang L,Chen S,Wang Z,Wei W,Huang Y,Peng H,Jiang YZ,Choe J,Lin S
Fri Mar 18 00:00:00 EDT 2022
A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids.
Nature cell biology
Gollwitzer P,Grützmacher N,Wilhelm S,Kümmel D,Demetriades C
Thu Sep 01 00:00:00 EDT 2022
p63 Directs Subtype-Specific Gene Expression in HPV+ Head and Neck Squamous Cell Carcinoma.
Frontiers in oncology
Glathar AR,Oyelakin A,Gluck C,Bard J,Sinha S
Sat Jul 16 00:00:00 EDT 2022
Complement C1q binding protein regulates T cells' mitochondrial fitness to affect their survival, proliferation, and anti-tumor immune function.
Cancer science
Tian H,Wang G,Wang Q,Zhang B,Jiang G,Li H,Chai D,Fang L,Wang M,Zheng J
Tue Mar 01 00:00:00 EST 2022
Effect of resistance training on satellite cells in old mice - a transcriptome study : implications for sarcopenia.
Bone & joint research
Hsu WB,Lin SJ,Hung JS,Chen MH,Lin CY,Hsu WH,Hsu WR
Tue Feb 01 00:00:00 EST 2022
Spiropachysine A suppresses hepatocellular carcinoma proliferation by inducing methuosis in vitro and in vivo.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Fang Y,Zhong T,Yang L,Luo F,Li Q,Wang D,Li Q,Fan Y,Yang X
Wed Jul 20 00:00:00 EDT 2022
Exposure to DEHP induces testis toxicity and injury through the ROS/mTOR/NLRP3 signaling pathway in immature rats.
Ecotoxicology and environmental safety
Hong Y,Zhou Y,Shen L,Wei Y,Long C,Fu Y,Wu H,Wang J,Wu Y,Wu S,Wei G
Mon Dec 20 00:00:00 EST 2021
CARS senses cysteine deprivation to activate AMPK for cell survival.
The EMBO journal
Yuan M,Yan R,Zhang Y,Qiu Y,Jiang Z,Liu H,Wang Y,Sun L,Zhang H,Gao P
Tue Nov 02 00:00:00 EDT 2021
CD82 protects against glaucomatous axonal transport deficits via mTORC1 activation in mice.
Cell death & disease
Ye M,Huang J,Mou Q,Luo J,Hu Y,Lou X,Yao K,Zhao B,Duan Q,Li X,Zhang H,Zhao Y
Sat Dec 11 00:00:00 EST 2021
The Deubiquitinase USP39 Promotes ESCC Tumorigenesis Through Pre-mRNA Splicing of the mTORC2 Component Rictor.
Frontiers in oncology
Zhao Y,Geng H,Liu G,Ji Q,Cheng X,Li X,Liu W,Thorne RF,Zhang R,Liu X
Tue Jun 15 00:00:00 EDT 2021
Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation.
Molecular cell
He A,Chen X,Tan M,Chen Y,Lu D,Zhang X,Dean JM,Razani B,Lodhi IJ
Thu Jul 02 00:00:00 EDT 2020
Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation.
Molecular cell
He A,Chen X,Tan M,Chen Y,Lu D,Zhang X,Dean JM,Razani B,Lodhi IJ
Thu Jul 02 00:00:00 EDT 2020
TXNIP deficiency mitigates podocyte apoptosis via restraining the activation of mTOR or p38 MAPK signaling in diabetic nephropathy.
Experimental cell research
Song S,Qiu D,Wang Y,Wei J,Wu H,Wu M,Wang S,Zhou X,Shi Y,Duan H
Sun Mar 15 00:00:00 EDT 2020
TXNIP deficiency mitigates podocyte apoptosis via restraining the activation of mTOR or p38 MAPK signaling in diabetic nephropathy.
Experimental cell research
Song S,Qiu D,Wang Y,Wei J,Wu H,Wu M,Wang S,Zhou X,Shi Y,Duan H
Sun Mar 15 00:00:00 EDT 2020
Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus.
Nature communications
Zhou X,Zhong Y,Molinar-Inglis O,Kunkel MT,Chen M,Sun T,Zhang J,Shyy JY,Trejo J,Newton AC,Zhang J
Mon Nov 30 00:00:00 EST 2020
Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus.
Nature communications
Zhou X,Zhong Y,Molinar-Inglis O,Kunkel MT,Chen M,Sun T,Zhang J,Shyy JY,Trejo J,Newton AC,Zhang J
Mon Nov 30 00:00:00 EST 2020
Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus.
Nature communications
Zhou X,Zhong Y,Molinar-Inglis O,Kunkel MT,Chen M,Sun T,Zhang J,Shyy JY,Trejo J,Newton AC,Zhang J
Mon Nov 30 00:00:00 EST 2020
Uptake of collagen type I via macropinocytosis cause mTOR activation and anti-cancer drug resistance.
Biochemical and biophysical research communications
Yamazaki S,Su Y,Maruyama A,Makinoshima H,Suzuki J,Tsuboi M,Goto K,Ochiai A,Ishii G
Thu May 21 00:00:00 EDT 2020
A glycolytic shift in Schwann cells supports injured axons.
Nature neuroscience
Babetto E,Wong KM,Beirowski B
Thu Oct 01 00:00:00 EDT 2020
mTOR Promotes Tissue Factor Expression and Activity in EGFR-Mutant Cancer.
Frontiers in oncology
Cong Y,Li Q,Zhang X,Chen Y,Yu K
Mon Sep 28 00:00:00 EDT 2020
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.
Molecular cell
Kovalski JR,Bhaduri A,Zehnder AM,Neela PH,Che Y,Wozniak GG,Khavari PA
Thu Feb 21 00:00:00 EST 2019
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.
Molecular cell
Kovalski JR,Bhaduri A,Zehnder AM,Neela PH,Che Y,Wozniak GG,Khavari PA
Thu Feb 21 00:00:00 EST 2019
The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance.
Autophagy
Huang X,Gan G,Wang X,Xu T,Xie W
Mon Jul 01 00:00:00 EDT 2019
Thioredoxin-interacting protein deficiency alleviates phenotypic alterations of podocytes via inhibition of mTOR activation in diabetic nephropathy.
Journal of cellular physiology
Song S,Qiu D,Shi Y,Wang S,Zhou X,Chen N,Wei J,Wu M,Wu H,Duan H
Sun Sep 01 00:00:00 EDT 2019
Thioredoxin-interacting protein deficiency alleviates phenotypic alterations of podocytes via inhibition of mTOR activation in diabetic nephropathy.
Journal of cellular physiology
Song S,Qiu D,Shi Y,Wang S,Zhou X,Chen N,Wei J,Wu M,Wu H,Duan H
Sun Sep 01 00:00:00 EDT 2019
Thioredoxin-interacting protein deficiency alleviates phenotypic alterations of podocytes via inhibition of mTOR activation in diabetic nephropathy.
Journal of cellular physiology
Song S,Qiu D,Shi Y,Wang S,Zhou X,Chen N,Wei J,Wu M,Wu H,Duan H
Sun Sep 01 00:00:00 EDT 2019
Thioredoxin-interacting protein deficiency alleviates phenotypic alterations of podocytes via inhibition of mTOR activation in diabetic nephropathy.
Journal of cellular physiology
Song S,Qiu D,Shi Y,Wang S,Zhou X,Chen N,Wei J,Wu M,Wu H,Duan H
Sun Sep 01 00:00:00 EDT 2019
Thioredoxin-interacting protein deficiency alleviates phenotypic alterations of podocytes via inhibition of mTOR activation in diabetic nephropathy.
Journal of cellular physiology
Song S,Qiu D,Shi Y,Wang S,Zhou X,Chen N,Wei J,Wu M,Wu H,Duan H
Sun Sep 01 00:00:00 EDT 2019
Thioredoxin-interacting protein deficiency alleviates phenotypic alterations of podocytes via inhibition of mTOR activation in diabetic nephropathy.
Journal of cellular physiology
Song S,Qiu D,Shi Y,Wang S,Zhou X,Chen N,Wei J,Wu M,Wu H,Duan H
Sun Sep 01 00:00:00 EDT 2019
Quantitative proteomics reveal the alterations in the spinal cord after myocardial ischemia‑reperfusion injury in rats.
International journal of molecular medicine
Li SY,Li ZX,He ZG,Wang Q,Li YJ,Yang Q,Wu DZ,Zeng HL,Xiang HB
Fri Nov 01 00:00:00 EDT 2019
mTOR-S6K1 pathway mediates cytoophidium assembly.
Journal of genetics and genomics = Yi chuan xue bao
Sun Z,Liu JL
Fri Feb 01 00:00:00 EST 2019
NOX1-Dependent mTORC1 Activation via S100A9 Oxidation in Cancer Stem-like Cells Leads to Colon Cancer Progression.
Cell reports
Ohata H,Shiokawa D,Obata Y,Sato A,Sakai H,Fukami M,Hara W,Taniguchi H,Ono M,Nakagama H,Okamoto K
Tue Jul 30 00:00:00 EDT 2019
Golgi phosphoprotein 3 (GOLPH3) promotes hepatocellular carcinoma progression by activating mTOR signaling pathway.
BMC cancer
Liu H,Wang X,Feng B,Tang L,Li W,Zheng X,Liu Y,Peng Y,Zheng G,He Q
Mon Jun 18 00:00:00 EDT 2018
UNBS5162 inhibits proliferation of human melanoma cells by inducing apoptosis via the PI3K/Akt pathway.
Molecular medicine reports
Shi X,Yang L,Xie J,Zhao Y,Cong J,Li Z,Li H,Cheng X,Fan J
Sat Sep 01 00:00:00 EDT 2018
Ribosomal protein S6 kinase1 coordinates with TOR-Raptor2 to regulate thylakoid membrane biosynthesis in rice.
Biochimica et biophysica acta
Sun L,Yu Y,Hu W,Min Q,Kang H,Li Y,Hong Y,Wang X,Hong Y
Fri Jul 01 00:00:00 EDT 2016
Ribosomal protein S6 kinase1 coordinates with TOR-Raptor2 to regulate thylakoid membrane biosynthesis in rice.
Biochimica et biophysica acta
Sun L,Yu Y,Hu W,Min Q,Kang H,Li Y,Hong Y,Wang X,Hong Y
Fri Jul 01 00:00:00 EDT 2016
Arctigenin functions as a selective agonist of estrogen receptor β to restrict mTORC1 activation and consequent Th17 differentiation.
Oncotarget
Wu X,Tong B,Yang Y,Luo J,Yuan X,Wei Z,Yue M,Xia Y,Dai Y
Tue Dec 20 00:00:00 EST 2016
Endostatin Prevents Dietary-Induced Obesity by Inhibiting Adipogenesis and Angiogenesis.
Diabetes
Wang H,Chen Y,Lu XA,Liu G,Fu Y,Luo Y
Wed Jul 01 00:00:00 EDT 2015
Endostatin Prevents Dietary-Induced Obesity by Inhibiting Adipogenesis and Angiogenesis.
Diabetes
Wang H,Chen Y,Lu XA,Liu G,Fu Y,Luo Y
Wed Jul 01 00:00:00 EDT 2015
Arctigenin exerts anti-colitis efficacy through inhibiting the differentiation of Th1 and Th17 cells via an mTORC1-dependent pathway.
Biochemical pharmacology
Wu X,Dou Y,Yang Y,Bian D,Luo J,Tong B,Xia Y,Dai Y
Sat Aug 15 00:00:00 EDT 2015
Arctigenin exerts anti-colitis efficacy through inhibiting the differentiation of Th1 and Th17 cells via an mTORC1-dependent pathway.
Biochemical pharmacology
Wu X,Dou Y,Yang Y,Bian D,Luo J,Tong B,Xia Y,Dai Y
Sat Aug 15 00:00:00 EDT 2015
Ghrelin promotes hepatic lipogenesis by activation of mTOR-PPARγ signaling pathway.
Proceedings of the National Academy of Sciences of the United States of America
Li Z,Xu G,Qin Y,Zhang C,Tang H,Yin Y,Xiang X,Li Y,Zhao J,Mulholland M,Zhang W
Tue Sep 09 00:00:00 EDT 2014
Ghrelin promotes hepatic lipogenesis by activation of mTOR-PPARγ signaling pathway.
Proceedings of the National Academy of Sciences of the United States of America
Li Z,Xu G,Qin Y,Zhang C,Tang H,Yin Y,Xiang X,Li Y,Zhao J,Mulholland M,Zhang W
Tue Sep 09 00:00:00 EDT 2014
Ghrelin promotes hepatic lipogenesis by activation of mTOR-PPARγ signaling pathway.
Proceedings of the National Academy of Sciences of the United States of America
Li Z,Xu G,Qin Y,Zhang C,Tang H,Yin Y,Xiang X,Li Y,Zhao J,Mulholland M,Zhang W
Tue Sep 09 00:00:00 EDT 2014
Ghrelin promotes hepatic lipogenesis by activation of mTOR-PPARγ signaling pathway.
Proceedings of the National Academy of Sciences of the United States of America
Li Z,Xu G,Qin Y,Zhang C,Tang H,Yin Y,Xiang X,Li Y,Zhao J,Mulholland M,Zhang W
Tue Sep 09 00:00:00 EDT 2014