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Product Details
IHC-00429
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 1650 and the C-terminus (residue 1708) of Human Rapamycin-Insensitive Companion of mTOR.
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Dog, Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon and White-tufted-ear marmoset
Target Information
RICTOR and MTOR (FRAP1) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AVO3 homolog; DKFZp686B11164; hAVO3; MGC39830; pianissimo; Rapamycin-insensitive companion of mTOR; RICTOR; RPTOR independent companion of MTOR, complex 2; TORC2-specific protein AVO3
Gene Aliases: AVO3; hAVO3; KIAA1999; PIA; RICTOR
UniProt ID: (Human) Q6R327
Entrez Gene ID: (Human) 253260
positive regulation of endothelial cell proliferation
embryo development
regulation of gene expression
peptidyl-serine phosphorylation
establishment of cell polarity
positive regulation of actin filament polymerization
establishment or maintenance of actin cytoskeleton polarity
T cell costimulation
actin cytoskeleton reorganization
TOR signaling
positive regulation of TOR signaling
regulation of actin cytoskeleton organization
regulation of peptidyl-serine phosphorylation
regulation of phosphorylation
positive regulation of catalytic activity
regulation of GTPase activity
phosphatidylinositol-mediated signaling
regulation of inflammatory response
positive regulation of peptidyl-tyrosine phosphorylation
regulation of protein kinase B signaling
positive regulation of protein kinase B signaling
regulation of establishment of cell polarity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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