Proteintech

S100 beta Monoclonal Antibody (1G10F4)

S100 beta Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 9

S100 beta Antibody (66616-1-IG) in IHC (P)

Immunohistochemistry of paraffin-embedded mouse brain tissue slide using 66616-1-Ig (S100B antibody) at dilution of 1:300 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

Product Image Gallery

Product Details

66616-1-IG

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

View 8 publications 8 publications

Product Specifications

Species Reactivity

Human, Mouse, Pig, Rat

Published species

Human, Mouse

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

1G10F4

Immunogen

S100 beta Fusion Protein Ag7440 (1-92 aa encoded by BC001766)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSELEKAMV ALIDVFHQYS GREGDKHKLK KSELKELINN ELSHFLEEIK EQEVVDKVME TLDNDGDGEC DFQEFMAFVA MVTTACHEFF EHE (1-92 aa encoded by BC001766)

Target Information

S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Platelet-Rich Plasma Gel-Loaded Collagen/Chitosan Composite Film Accelerated Rat Sciatic Nerve Injury Repair.

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α-Synuclein induces prodromal symptoms of Parkinson's disease via activating TLR2/MyD88/NF-κB pathway in Schwann cells of vagus nerve in a rat model.

Journal of neuroinflammation

Cheng Y,Tong Q,Yuan Y,Song X,Jiang W,Wang Y,Li W,Li Y,Zhang K

Tue Feb 14 00:00:00 EST 2023

Motor neurons transplantation alleviates neurofibrogenesis during chronic degeneration by reversibly regulating Schwann cells epithelial-mesenchymal transition.

Experimental neurology

Wu Z,Ding H,Chen Y,Huang C,Chen X,Hu H,Chen Y,Zhang W,Fang X

Sun Jan 01 00:00:00 EST 2023

Repetitive mild TBI causes pTau aggregation in nigra without altering preexisting fibril induced Parkinson's-like pathology burden.

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Delic V,Karp JH,Guzman M,Arismendi GR,Stalnaker KJ,Burton JA,Murray KE,Stamos JP,Beck KD,Sokratian A,West AB,Citron BA

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Adtrp regulates thermogenic activity of adipose tissue via mediating the secretion of S100b.

Cellular and molecular life sciences : CMLS

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Adtrp regulates thermogenic activity of adipose tissue via mediating the secretion of S100b.

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Fri Jul 08 00:00:00 EDT 2022

Adtrp regulates thermogenic activity of adipose tissue via mediating the secretion of S100b.

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Fri Jul 08 00:00:00 EDT 2022

Adtrp regulates thermogenic activity of adipose tissue via mediating the secretion of S100b.

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Fri Jul 08 00:00:00 EDT 2022

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Nogo-C Inhibits Peripheral Nerve Regeneration by Regulating Schwann Cell Apoptosis and Dedifferentiation.

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Resistin-Inhibited Neural Stem Cell-Derived Astrocyte Differentiation Contributes to Permeability Destruction of the Blood-Brain Barrier.

Neurochemical research

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Mon Apr 01 00:00:00 EDT 2019

Resistin-Inhibited Neural Stem Cell-Derived Astrocyte Differentiation Contributes to Permeability Destruction of the Blood-Brain Barrier.

Neurochemical research

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Interaction of DCF1 with ATP1B1 induces impairment in astrocyte structural plasticity via the P38 signaling pathway.

Experimental neurology

Wang J,Zhou F,Wang D,Li J,Lu D,Li Q,Zhou H,Li W,Wang Q,Wu Y,Xie J,Wen T

Sun Apr 01 00:00:00 EDT 2018

Interaction of DCF1 with ATP1B1 induces impairment in astrocyte structural plasticity via the P38 signaling pathway.

Experimental neurology

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Bioinformatics

Protein Aliases: Protein S100-B; S-100 calcium-binding protein, beta chain; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium binding protein beta (neural); S100 calcium-binding protein B; S100 calcium-binding protein beta (neural); S100 calcium-binding protein, beta (neural); S100 protein beta chain; S100 protein, beta polypeptide, neural

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Gene Aliases: AI850290; Bpb; NEF; S100; S100-B; S100B; S100beta; S100P

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UniProt ID: (Human) P04271, (Mouse) P50114, (Rat) P04631

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Entrez Gene ID: (Human) 6285, (Pig) 100623510, (Mouse) 20203, (Rat) 25742

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Function(s)

calcium ion binding protein binding zinc ion binding identical protein binding protein homodimerization activity S100 protein binding tau protein binding calcium-dependent protein binding RAGE receptor binding receptor binding metal ion binding calmodulin-related

Process(es)

axonogenesis central nervous system development learning or memory memory cell proliferation positive regulation of cell proliferation regulation of cell shape positive regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling innate immune response regulation of neuronal synaptic plasticity astrocyte differentiation response to glucocorticoid response to methylmercury long-term synaptic potentiation cellular response to hypoxia negative regulation of skeletal muscle cell differentiation energy reserve metabolic process cellular calcium ion homeostasis regulation of cytokine biosynthetic process regulation of long-term neuronal synaptic plasticity positive regulation of synaptic transmission

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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S100 beta Monoclonal Antibody (1G10F4)

S100 beta Antibody (66616-1-IG) in IHC (P)

Product Details

66616-1-IG

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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