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S100B Antibody (MA5-49443) in ELISA
ELISA analysis of S100B, microtiter wells were coated with S100B Monoclonal Antibody (KT169), HRP (Product # MA5-49443) at 3 µg/mL. S100B was used as the antigen. Peroxidase conjugated mouse anti-human S100B monoclonal antibody (KT169) was used as the detection antibody. Result: KT169 and KT170 can be used as a matched antibody pair to detect and quantify the concentration of S100B.
Product Details
MA5-49443
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
KT169
Immunogen
Recombinant Human S100B(HRP)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3093294
Product Specific Information
This product was used in a Sandwich ELISA.
Target Information
S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein S100-B; S-100 calcium-binding protein, beta chain; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium binding protein beta (neural); S100 calcium-binding protein B; S100 calcium-binding protein, beta (neural); S100 protein beta chain
Gene Aliases: NEF; S100; S100-B; S100B; S100beta
UniProt ID: (Human) P04271
Entrez Gene ID: (Human) 6285
axonogenesis
central nervous system development
learning or memory
memory
cell proliferation
positive regulation of cell proliferation
regulation of cell shape
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
regulation of neuronal synaptic plasticity
astrocyte differentiation
response to glucocorticoid
response to methylmercury
long-term synaptic potentiation
cellular response to hypoxia
negative regulation of skeletal muscle cell differentiation
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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